Navigation Links
Simple chemical cocktail shows first promise for limb re-growth in mammals
Date:4/6/2011

Move over, newts and salamanders. The mouse may join you as the only animal that can re-grow their own severed limbs. Researchers are reporting that a simple chemical cocktail can coax mouse muscle fibers to become the kinds of cells found in the first stages of a regenerating limb. Their study, the first demonstration that mammal muscle can be turned into the biological raw material for a new limb, appears in the journal ACS Chemical Biology.

Darren R. Williams and Da-Woon Jung say their "relatively simple, gentle, and reversible" methods for creating the early stages of limb regeneration in mouse cells "have implications for both regenerative medicine and stem cell biology." In the future, they suggest, the chemicals they use could speed wound healing by providing new cells at the injured site before the wound closes or becomes infected. Their methods might also shed light on new ways to switch adult cells into the all-purpose, so-called "pluripotent," stem cells with the potential for growing into any type of tissue in the body.

The scientists describe the chemical cocktail that they developed and used to turn mouse muscle fibers into muscle cells. Williams and Jung then converted the muscle cells turned into fat and bone cells. Those transformations were remarkably similar to the initial processes that occur in the tissue of newts and salamanders that is starting to regrow severed limbs.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related medicine news :

1. Simple blood test detects early emphysema in smokers before symptoms appear
2. Simple blood test at discharge could help reduce hospital readmissions for heart failure patients
3. Radio-guided surgery a safe and simple way to remove potentially cancerous nodules in the lung
4. Simple spit and blood tests might detect burnout before it happens
5. Quick, Simple Test Can Detect Concussion in Athletes
6. Toward a fast, simple test for detecting cholera rampaging in 40 countries
7. Simple feedback could be effective therapy for addictive behaviors
8. Simple Screen May Help Spot Depression in College Students
9. Wounded Congresswoman Responds to Simple Commands
10. Simple fingertip test may identify breast cancer patients at risk for carpal tunnel syndrome
11. Simple Travel Tips Can Help Keep Pets Safe
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/21/2017)... ... September 21, 2017 , ... Innovatum will demonstrate capabilities of ... Healthcare Conference 2017 in Chicago, IL on October 17-19, 2017. This unique development ... improving patient safety. , Microscan , a global technology leader in ...
(Date:9/21/2017)... ... ... FlipBelt, the fitness brand that specializes in problem solving fitness accessories, has ... the launch of their FlipBelt Crops. , The new fitness bottoms feature an integrated ... at the gym, on the trail, or on-the-go. , “We always thought the FlipBelt ...
(Date:9/20/2017)... ... 2017 , ... FirstAlign ( http://www.firstalign.com ), combines strategies and ... (AI) thinking, announced today the launch of its revamped web presence. , ... offers a more comprehensive understanding of the organization’s business and machine learning solutions. ...
(Date:9/20/2017)... ... September 20, 2017 , ... ... company specializing in medical device compliance and commercialization, has just released a ... activities. , FDA is more adamant than ever about medical device, pharmaceutical, ...
(Date:9/20/2017)... ... 2017 , ... Compliancy Group is proud to announce that ... helped another long-time client pass their Department of Health and Human Services (HHS) ... Thanks to the help of the Compliancy Group's Audit Response Program™, not a ...
Breaking Medicine News(10 mins):
(Date:9/9/2017)... Sept. 9, 2017  Eli Lilly and Company (NYSE: ... secondary endpoint data for lasmiditan, an investigational, oral, first-in-class ... statistically significant improvements compared to placebo in the Phase ... at the 18th Congress of the International Headache Society ... "The data presented today demonstrate lasmiditan,s potential to reduce ...
(Date:9/7/2017)... NuvoAir (formerly called Pond Healthcare Innovation), the company ... Novartis Pharma AG to distribute NuvoAir,s spirometry technology to physicians ... spirometry platform and Novartis, commitment to address the unmet medical ... ... "We ...
(Date:9/6/2017)...  Medical professionals are expected to continuously ... their patients. Medical simulations offer clinicians the ... Simulation provides a safe method for teaching ... refine techniques and build confidence, without putting ... such as augmented reality, will now provide ...
Breaking Medicine Technology: