Navigation Links
Simple Test May Identify Breast Cancer Subtypes
Date:5/7/2010

These classifications can help explain different outcomes for women with similar-looking tumors, expert says

FRIDAY, May 7 (HealthDay News) -- Classification of breast cancer into subtypes can be achieved through a simple genetic test that uses only three genes, U.S. researchers say.

They analyzed 32 gene expression data sets, including more than 4,600 breast cancer patients and six classification models.

"We studied these models in terms of concordance and prognostic value and, for the first time, we estimated their robustness: that is, their capacity to assign the same tumors to the same molecular subtypes whatever the gene expression data used to fit this model," Dr. Benjamin Haibe-Kains, of the Dana-Farber Cancer Institute in Boston, said in a news release from the European Society for Medical Oncology.

A simple test that uses three genes -- ESR1, ERBB2 and AURKA -- was found to be highly effective in identifying breast cancer subtypes.

The study was to be presented Thursday at the IMPAKT Breast Cancer Conference in Brussels, Belgium.

It's long been known that breast cancer isn't one biologically identical disease, but includes several molecular subtypes that have distinct gene expression profiles.

"It is these differences that explain, at least in part, why patients who have tumors that appear to be similar may experience completely different clinical outcomes such as prognosis and response to anticancer therapies," Haibe-Kains said in the news release. "Thus, there is an urgent need for developing a robust tool to provide clinicians with guidance for classifying breast cancer molecular subtypes, which could then aid in making therapeutic decisions."

More information

The American Cancer Society has more about breast cancer.




'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. SimpleWebBox Offers Free Websites for Non-Profit Organizations
2. Monkey Brain Hardwired for Simple Math
3. Shamy & Shamy Launches New Web Site Providing Simple Access to Free Online Resources for New Jersey Court System
4. Father Channels His Grief into Advocacy, Promotes Simple Actions to Make Hospitals Safer for Children
5. Simple Concussion Test Measures Reaction Time
6. UAB-led study shows simple steps could reduce stillbirths by up to 1 million
7. NationalCreditReport.com Offers Simple Tax Saving Tips That Can Improve Credit Scores
8. Many With Arthritis Find Simple Solutions for Relief
9. Simple Forms Help Docs Do Better Breast Exams
10. The Simple and Revolutionary Power to OUTSMART YOUR GENES Out April 6th -- Predictive Medicine Pioneer Dr. Brandon Colby Releases Book
11. Simple Test May Spot Early Lung Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... (PRWEB) December 22, 2014 Coral Gables is ... service , Lice Troopers, with its new clinic location set ... Florida, takes the hassle out of dealing with this common ... one of their two salon clinic locations in South Florida, ... location. , The decision to expand developed naturally out of ...
(Date:12/22/2014)... International efforts to combat ... are receiving further support from recent initiatives ... (NGOs) and other charitable organizations. While research ... responders, patients and others can immediately benefit ... CmTP MediDefense system , which includes ...
(Date:12/22/2014)... (PRWEB) December 22, 2014 Super Saturday, ... Friday this year as the busiest day in the ... retailers, The Grass Station had a steady pre-Christmas stream ... gifts, this past Saturday. , “I definitely intend to ... Robert, a Denver resident who was enjoying The Grass ...
(Date:12/22/2014)... Georgia (PRWEB) December 22, 2014 The MedTech ... Inc, a wholly owned subsidiary of PartnerTech AB of ... U.S. having recently achieved additional ISO Certification. , All signs ... in employment and the likelihood of a repeal of the ... Act . The industry is anticipating annual growth of 9.3% ...
(Date:12/22/2014)... Luxury Linen purveyor Peacock Alley ... to provide logistics and support for one of Dallas’ ... a long history of giving back to the community in ... year's Toy Drive were Whataburger® and 99.5 The Wolf. , ... holidays. Providing gifts to children who would otherwise not receive ...
Breaking Medicine News(10 mins):Health News:Professional In-Home All-Natural Lice Removal Service Expands to Coral Gables and surrounding areas. 2Health News:Novel Biostatic Antimicrobial Technology From Clearstream-mPact Technology Partnership (CmTP) Offers Effective Protection Against Transmission of Ebola Virus 2Health News:Novel Biostatic Antimicrobial Technology From Clearstream-mPact Technology Partnership (CmTP) Offers Effective Protection Against Transmission of Ebola Virus 3Health News:Novel Biostatic Antimicrobial Technology From Clearstream-mPact Technology Partnership (CmTP) Offers Effective Protection Against Transmission of Ebola Virus 4Health News:Novel Biostatic Antimicrobial Technology From Clearstream-mPact Technology Partnership (CmTP) Offers Effective Protection Against Transmission of Ebola Virus 5Health News:Customers at Colorado’s Grass Station Say They’re Enjoying the Experience of Legally Purchasing Marijuana this Year to Give as Christmas Presents to Friends and Family 2Health News:PartnerTech Inc. Poised for Growth in MedTech 2Health News:Peacock Alley and Community Partners of Dallas Fulfill an Estimated 12,000 Holiday Wishes for Deserving Children 2
... Vancouver Career College ... ... Career College in Surrey are digging through their closets to find clothing to. Now they’re ... need., , , , ,“Every day we focus on building a community here on campus ...
... Research Hospital and the University of Florida Proton Therapy Institute ... Jude patients. The announcement follows the approval of the first ... rare brain cancers in children younger than 3 years old. ... refer patients to receive proton therapy at the UF Proton ...
... Bright Horizons Family Solutions® today announced that it ... by the Boston Globe. The prestigious ranking on the Globe ... has always worked to support its employees and despite the ... on fostering a culture where employees feel valued and supported at ...
... computerized alerts can help curb the impulse to ... in the August issue of Journal of ... received computerized alerts, which compared medication brands, they ... marketed sleep medications to comparable generic equivalents. ...
... of those hurt are under 16, researchers say , MONDAY, ... the United States in recent years, rising by 160 percent ... , However, the total number of injuries related to hot ... remains fairly small at about 6,600 per year. , ...
... today the acquisition of App Tech Global, Inc., which will ... Nutrition,s name will be changed to App Tech, Corp. and ... App Tech Global, Inc. , App Tech is developing mobile ... App Tech is focused on multi platform apps designed to ...
Cached Medicine News:Health News:Surrey College Students Collect Clothing for Women and Children 2Health News:St. Jude Children's Research Hospital and UF Proton Therapy Institute to Begin Proton Therapy Clinical Trial 2Health News:St. Jude Children's Research Hospital and UF Proton Therapy Institute to Begin Proton Therapy Clinical Trial 3Health News:St. Jude Children's Research Hospital and UF Proton Therapy Institute to Begin Proton Therapy Clinical Trial 4Health News:Bright Horizons Named One of Boston Globe 100's Top Places to Work 2Health News:Computerized support keeps prominence of name brand drugs at bay 2Health News:Hot-Tub Injuries on the Rise 2
(Date:12/19/2014)... 2014  Monarch America Inc. (OTCQB: CANK) ("Monarch America" ... to provide this review of the Company,s recent achievements ... "Over this past year, we achieved many of ... proud to say that Monarch America is in a ... ever been," stated Eric Hagen , CEO of ...
(Date:12/19/2014)... YORK , Dec. 18, 2014 Somewhere ... addressing hearing health was forgotten. But Audicus , ... to hear better this new year. Hearing ... facing the aging population, though it is often unaddressed. ... in four has a hearing aid, mainly due to ...
(Date:12/19/2014)... , Dec. 18, 2014  Decision Resources Group finds ... United States will increase to a value ... primarily driven by expansion in the large direct energy ... will be increasingly adopted due to the advantages they ... Other key findings from Decision Resources Group,s coverage of ...
Breaking Medicine Technology:Monarch America Inc. CEO Reviews Recent Achievements and Provides Outlook for 2015 2Monarch America Inc. CEO Reviews Recent Achievements and Provides Outlook for 2015 3Audicus Will Help People Resolve to Hear Better in 2015 2U.S. Laparoscopic Device Market Will Reach Over $4.3 Billion by 2023 2U.S. Laparoscopic Device Market Will Reach Over $4.3 Billion by 2023 3
... Md., July 25, 2011 The Food and Drug Administration (FDA) has ... (Logo: http://photos.prnewswire.com/prnh/20090824/FDALOGO ) a wart ... unapproved drug sold as a "sexual enhancer" a diabetes medicine ... that can lower a child,s IQ when taken by the mother ...
... Accuray Incorporated (Nasdaq: ARAY ), the ... Robotic Radiosurgery System at five renowned academic oncology centers in ... at Pennsylvania Hospital in Philadelphia, PA; The Royal ... Center at St. Bartholomew,s Hospital in London, England; ...
Cached Medicine Technology:FDA CONSUMER HEALTH INFORMATION - FDA's MedWatch Safety Alerts: June 2011 2Five Leading Academic Hospitals Install the CyberKnife System for Dedicated Radiosurgery 2Five Leading Academic Hospitals Install the CyberKnife System for Dedicated Radiosurgery 3
Adjust-A-Tip cautery....
6 mm, 45 degree upwards, detachable....
Sabre 180 is a powerful niche generator....
The ExcaliburPlus PC is the most powerful isolated ESU with 10,000 V PTP in spray coag....
Medicine Products: