Navigation Links
Silk and cellulose biologically effective for use in stem cell cartilage repair
Date:5/7/2013

Over 20 million people in Europe suffer from osteoarthritis which can lead to extensive damage to the knee and hip cartilage. Stem cells offer a promising way forward but a key challenge has been to design a 'smart material' that is biologically effective for cartilage tissue regeneration. Now researchers have identified a blend of naturally occurring fibres such as cellulose and silk that makes progress towards affordable and effective cell-based therapy for cartilage repair a step closer.

The EPSRC-funded study, published in Biomacromolecules and undertaken by University of Bristol researchers, explored the feasibility of using natural fibres such as silk and cellulose as stem cell scaffolds the matrix to which stem cells can cling to as they grow.

Both cellulose and silk are commonly used in textiles but the researchers demonstrated an unexpected use for the two natural polymers when mixed with stem cells. The team treated blends of silk and cellulose for use as a tiny scaffold that allows adult connective tissue stem cells to form into preliminary form of chondrocytes the cells that make healthy tissue cartilage and secrete extracellular matrix similar to natural cartilage.

Dr Wael Kafienah, lead author from the University's School of Cellular and Molecular Medicine, said: "We were surprised with this finding, the blend seems to provide complex chemical and mechanical cues that induce stem cell differentiation into preliminary form of chondrocytes without need for biochemical induction using expensive soluble differentiation factors. This new blend can cut the cost for health providers and makes progress towards effective cell-based therapy for cartilage repair a step closer."

Dr Sameer Rahatekar, lead author from the University's Advanced Composite Centre for Innovation and Science (ACCIS), added: "We used ionic liquids for the first time to produce cellulose and silk scaffolds for stem cells differ
'/>"/>

Contact: Caroline Clancy
caroline.clancy@bristol.ac.uk
44-011-792-88086
University of Bristol
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Men Biologically Programmed to Steer Clear of Friends Wives
2. Exercise proves to be ineffective against care home depression
3. Weight loss surgery safe and effective for an expanded group of patients
4. Mariner Biomedical Announces Results From an Independent Laboratory Confirming Deter Insect Repellent™ Effectively Repels Mosquitoes for 6 Hours
5. CHOP, Penn Study is the First to Compare Treatments for HIV-Infected Children in Low-Resource Settings; Results Show Less-Used Regimen is More Effective
6. Study compares effectiveness of 2 vs. 3 doses of HPV vaccine for girls and young women
7. New Medical Study Finds Reed Migraine Centers’ Migraine Treatment Highly Effective in Controlling Severe Pain in Majority of Patients
8. Cleveland Clinic research shows Internet-based program effective in reducing stress
9. New Research Shows Programs like Recovery Associates Offer the Most Effective Type of Treatment for Drug and Alcohol Addiction
10. Stanford study examines cost-effectiveness of helicopter transport of trauma victims
11. Research finds targeted screening for hepatitis C is cost-effective
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... ... June 30, 2015 , ... ... Rehab”. The video focuses on the rehab center’s patients and their experiences at ... the best quality of services available. Each patient attests to the high rating, ...
(Date:6/30/2015)... ... June 30, 2015 , ... According to a June 15th report ... study how sensory stimuli can be used to “decrease children’s anxiety and negative responses ... with autism, will compare patient experience in a “typical dental environment” with one that ...
(Date:6/30/2015)... Long Beach, CA (PRWEB) , ... June 30, 2015 , ... ... Sea Skilled Nursing”, which features multiple patient and family member testimonials. Medicare rated the ... the country. Broadway plans to use the video to give future patients a firsthand ...
(Date:6/30/2015)... New York, NY (PRWEB) , ... June 30, ... ... international shipping when buying eyeglasses online , finally its here, ... and offer express shipping rates, for many location, ask about shipping with DHL ...
(Date:6/30/2015)... New York (PRWEB) , ... June 30, 2015 ... ... ( http://www.xareltolawsuit2015.com/ ) currently pending in a federal multidistrict litigation now underway in ... Court convenes its next monthly Status Conference. According to the Court’s calendar, that ...
Breaking Medicine News(10 mins):Health News:Patients of University Post-Acute Rehab Support Five-Star Rating in New Video 2Health News:New Study Aims to Determine if Sensory Stimuli can Ease Dental Anxiety in Children, Notes Medical Center Dental Care 2Health News:New Study Aims to Determine if Sensory Stimuli can Ease Dental Anxiety in Children, Notes Medical Center Dental Care 3Health News:Broadway by the Sea Video Promotes Top Quality Service 2Health News:Eyeglasses Online - Express Glasses Announcing New International Shipping Using DHL 2Health News:Progress of Federal Xarelto Lawsuits Pending in Multidistrict Litigation to Be Discussed During July 9th Status Conference 2Health News:Progress of Federal Xarelto Lawsuits Pending in Multidistrict Litigation to Be Discussed During July 9th Status Conference 3
... the cost of such tests is a potential stumbling block, ... the heart arteries for calcium deposits can help predict future ... that adding such scans to routine checkups would be worth ... of potential heart trouble, said Dr. Diane Bild, deputy director ...
... Michael D. Farley has,joined the Lupus ... Washington,DC as the organization,s Chief Operating Officer, ... overall organizational administration and,field development. Farley has ... including serving most recently as the,interim CEO ...
... Inc.,(Nasdaq: EMAG ), a leader in ... healthcare networks, announced today that its,HeartSuite(TM) VERICIS(R) ... for,Cardiology PACS*. HeartSuite is Emageon,s comprehensive suite ... information,management, hemodynamic monitoring, advanced visualization and content,management. ...
... PURCELLVILLE, Va., March 26 At a panel,discussion ... Force Colonel,Mike Turner, a candidate for U.S. Congress ... for Professor Judy Feder, his opponent,in the June ... Frank,Wolf in what is expected to be a ...
... Courses Improve Patient Care and Address State Regulations, ... Care Compliance,Strategies, Inc.), the leading provider of online ... with University,HealthSystem Consortium (UHC) to deliver a suite ... 11 courses with multimedia content and,healthcare specific case ...
... of Other Medicare Providers at Risk, WASHINGTON, ... drug plans (PDPs) pay drugstores twice as fast,as ... and its,beneficiaries at least $3.3 billion over the ... (PwC) that was commissioned by the,Pharmaceutical Care Management ...
Cached Medicine News:Health News:Calcium Scans Help Predict Coronary Risk 2Health News:Michael D. Farley Appointed Chief Operating Officer of Lupus Foundation of America, Inc. 2Health News:Emageon Receives 'Best in KLAS' Cardiology PACS Award 2Health News:Democrat Mike Turner Backs Single-Payer Healthcare; Opponent Feder Undecided 2Health News:HCCS Partners With UHC to Deliver Cultural Competency Courses 2Health News:HCCS Partners With UHC to Deliver Cultural Competency Courses 3
(Date:6/30/2015)... --  Millar, Inc. , a leader in catheter-based and ... of Craig Thummel , President/CEO and member of ... to the Company. The Company also announced its leadership ... Executive Management team as his successors. The Board of ... of Sales and Marketing, as President, and also a ...
(Date:6/30/2015)... 2015 Dipexium Pharmaceuticals, Inc. (Nasdaq: ... on the development and commercialization of Locilex® (pexiganan ... previously announced underwritten public offering of 1,480,000 shares ... over-allotment option in full to purchase an additional ... net proceeds to Dipexium are expected to be ...
(Date:6/30/2015)... , June 24, 2015 ... the addition of the "Global Array Instruments ... The global array instruments market to grow ... period 2014-2019 The global array instruments market ... protein microarrays, and others including tissue microarrays and ...
Breaking Medicine Technology:Millar, Inc. Announces Leadership Changes 2Millar, Inc. Announces Leadership Changes 3Dipexium Announces Closing of Public Offering of Common Stock 2Dipexium Announces Closing of Public Offering of Common Stock 3Global Array Instruments Market 2015-2019 - Advances in Personalized Medicines with Affymetrix, Agilent Technologies & Illumina Dominating 2
... Biosciences, Inc., a privately held company leading the development ... Steven L. Zelenkofske, D.O., F.A.C.C., Senior Vice President and ... College of Chest Physicians (ACCP) Coagulation and Heart Disease ...  The abstract is titled "Sustained Inhibition of Factor IXa ...
... JEDDAH, Saudi Arabia, Nov. 2, 2010 The Saudi ... it has signed an agreement with Varian Medical Systems ... for magnetic resonance-guided radiation therapy (MRgRT™). Under ... treatment solution that combines IMRIS, unique movable magnetic resonance ...
Cached Medicine Technology:Regado Biosciences, Inc. Presents the First-In-Human Clinical Experience with REG2 at the American College of Chest Physicians (ACCP) Coagulation and Heart Disease Sessions in Vancouver, BC, Canada on November 2, 2010 2Regado Biosciences, Inc. Presents the First-In-Human Clinical Experience with REG2 at the American College of Chest Physicians (ACCP) Coagulation and Heart Disease Sessions in Vancouver, BC, Canada on November 2, 2010 3Saudi Arabia's King Abdullah International Research Center Signs With Varian Medical Systems and IMRIS for Future Technology for Use in Radiotherapy 2Saudi Arabia's King Abdullah International Research Center Signs With Varian Medical Systems and IMRIS for Future Technology for Use in Radiotherapy 3Saudi Arabia's King Abdullah International Research Center Signs With Varian Medical Systems and IMRIS for Future Technology for Use in Radiotherapy 4
The URCA (Uric acid) method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of uric acid in serum, plasma and urine....
For the quantitative in vitro determination of apolipoprotein A-1 (apo A-1) in serum and plasma. For use as an aid if assessing the risk of coronary artery disease....
The GGT method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of g-glutamyl transferase activity in serum and plasma...
For the quantitative in vitro determination of Triglycerides in serum and plasma....
Medicine Products: