Navigation Links
Silicone Breast Implants Might Raise Risk of Rare Lymphoma
Date:11/4/2008

But researchers stress absolute chances of disease are still small

TUESDAY, Nov. 4 (HealthDay News) -- Women with silicone breast implants may have a higher risk of developing a rare form of lymphoma, new research suggests.

But the absolute risk of developing this cancer is still tiny, amounting to about 0.1 to 0.3 per 100,000 women with implants each year, according to the Dutch authors of a study published in the Nov. 5 issue of the Journal of the American Medical Association.

"Doctors should be aware of this . . . but it's not something women should worry about," said Dr. Mitchell Smith, head of the lymphoma service at Fox Chase Cancer Center in Philadelphia. "People with implants have a one in many hundreds of thousands or one in a million chance of developing this cancer."

More importantly, Smith said, the finding might help scientists understand the biology of this particular malignancy.

Silicone breast implants have engendered decades of controversy. In 2006, the U.S. Food and Drug Administration lifted a 14-year ban on their commercial use, giving approval to two companies, Allergan Inc., of Irvine, Calif., and Mentor Corp, of Santa Barbara, Calif., to market the implants to all women aged 22 and older.

Neither company responded to requests from HealthDay for comment on the finding.

The implants had been removed from the market in 1992, following suspicions that they might cause cancer or certain autoimmune diseases. There were also concerns that the implants might interfere with the accuracy of breast cancer screening, or that ruptures would cause other health problems.

Researchers have identified previous cases of non-Hodgkin lymphoma in women with breast implants, and most of these were anaplastic large T-cell lymphoma (ALCL).

Normally, ALCL is exceedingly rare, representing 3 percent or less of all non-Hodgkin lymphoma in adults, and there are no known risk factors.

The authors of this study, at the Netherlands Cancer Institute in Amsterdam, searched a national database in the Netherlands for all cases of lymphoma in the breast diagnosed between 1990 and 2006.

They found 11 patients with ALCL, five of whom had had breast implants one to 23 years before their diagnosis. This was out of a total population of 8 million Dutch women over 17 years.

Compared with women who had other types of lymphoma in the breast, women with silicone breast implants had an 18-fold greater risk for developing ALCL.

The authors hypothesized that an immune system response related to placement of the implants or toxic damage from the implants might explain the association.

"There has been a lot of information about silicone and autoimmune disorders," Smith said. "Lymphomas do occur in other immune-deficiency states where you have chronic stimulation of parts of the immune system. It makes some sort of sense that this could happen."

More information

Visit The Leukemia & Lymphoma Society for more on different types of lymphoma.



SOURCES: Mitchell Smith, M.D., Ph.D., head, lymphoma service, Fox Chase Cancer Center, Philadelphia; Nov. 5, 2008, Journal of the American Medical Association


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Breast Augmentation Raleigh Natural Looking Results with Saline or Silicone Implants
2. ASPS Studies Re-Evaluate Psychological Benefits and Health Concerns of Silicone Breast Implants
3. Little Evidence Silicone Breast Implants Harm Health
4. LifeCare Wins Breastfeeding-Friendly Business Award from Connecticut Breastfeeding Coalition
5. Samsung and Susan G. Komen for the Cure(R) Launch Historic Breast Cancer Alliance
6. Excess Weight Seems to Boost Breast Cancer Risk
7. Winners Selected as Beautiful Warriors by Ford Warriors in Pink and Readers Digest for Exemplifying the Fight Against Breast Cancer
8. Natural Hormone Balance: Gaining Ground in the Fight Against Breast Cancer
9. Vigorous Exercise Can Cut Breast Cancer Risk
10. National Breast Cancer Coalition Survey Reveals That Lack of Commitment and Funding Impede the Fight Against Breast Cancer
11. Rowenta, Iron Manufacturer, Pits Marines, Quilters, Mothers and Daughters Against One Another to Help Iron Out Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Silicone Breast Implants Might Raise Risk of Rare Lymphoma
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... agency serving communities in the greater Dallas, Miami, and Raleigh regions, is organizing ... fighting to overcome a rare and deadly chromosome abnormality. , After struggling since ...
(Date:10/13/2017)... ... 2017 , ... The American Board of Family Medicine's (ABFM) Board of Directors ... Officer, succeeding Dr. James C. Puffer upon his retirement. Dr. Newton will serve in ... retirement at the end of 2018. Upon assuming the role of President and CEO ...
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of ... ElderCounsel, a national organization of elder law and special needs planning attorneys. “Membership in ... It also provides a forum to network with elder law attorneys nationwide,” said Somekh. ...
(Date:10/13/2017)... ... 13, 2017 , ... Ellevate Network, the leading network for professional women, brought ... gender equality at their inaugural Summit in New York City in June. The event ... audience of over 3 million. To watch the Mobilize Women video, click here ...
(Date:10/13/2017)... VA (PRWEB) , ... October 13, 2017 , ... ... of DevOps and Agile Software Development, has been awarded a contract by the ... Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... 2017   ZirMed Inc ., a recognized leader in ... it has been ranked #1 by its users for the ... 2017 User Survey. ZirMed was recognized as the top-ranked end-to-end ... medical centers over 200 beds and holds one of the ... survey history. ...
(Date:9/13/2017)... ATLANTA , Sept. 13, 2017   OrthoAtlanta ... to the Atlanta Football Host Committee (AFHC) for the 2018 ... Monday, Jan. 8, 2018, at Mercedes-Benz Stadium in ... part of the AFHC "I,m In" campaign, participating in many ... ...
(Date:9/12/2017)... Sept. 12, 2017  ValGenesis Inc., the global ... is pleased to announce the appointment of Dr. ... its Board of Directors and Chairman of Advisory ... life science companies to manage their entire validation ... paper in this process. Furthermore, ValGenesis VLMS enables ...
Breaking Medicine Technology: