Navigation Links
Silent stroke can cause Parkinson's disease
Date:12/18/2012

Scientists at The University of Manchester have for the first time identified why a patient who appears outwardly healthy may develop Parkinson's disease.

Whilst conditions such as a severe stroke have been linked to the disease, for many sufferers the tremors and other symptoms of Parkinson's disease can appear to come out of the blue. Researchers at the university's Faculty of Life Sciences have now discovered that a small stroke, also known as a silent stroke, can cause Parkinson's disease. Their findings have been published in the journal "Brain Behaviour and Immunity".

Unlike a severe stroke, a silent stroke can show no outward symptoms of having taken place. It happens when a blood vessel in the brain is blocked for only a very short amount of time and often a patient won't know they have suffered from one. However, it now appears one of the lasting effects of a silent stroke can be the death of dopaminergic neurons in the substantia nigra in the brain, which is an important region for movement coordination.

Dr. Emmanuel Pinteaux led the research: "At the moment we don't know why dopaminergic neurons start to die in the brain and therefore why people get Parkinson's disease. There have been suggestions that oxidative stress and aging are responsible. What we wanted to do in our study was to look at what happens in the brain away from the immediate area where a silent stroke has occurred and whether that could lead to damage that might result in Parkinson's disease."

The team induced a mild stroke similar to a silent stroke in the striatum area of the brain in mice. They found there was inflammation and brain damage in the striatum following the stroke, which they had expected. What the researchers didn't expect was the impact on another area of the brain, the substantia nigra. When they analysed the substantia nigra they recorded a rapid loss of Substance P (a key chemical involved in its functions) as well as in
'/>"/>

Contact: Morwenna Grills
Morwenna.Grills@manchester.ac.uk
44-161-275-2111
University of Manchester
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Neurocritical Care & Stroke Conference slated for March 2013
2. Telestroke networks can be cost-effective for hospitals, good for patients
3. High Blood Pressure Poses Bigger Stroke Risk for Blacks, Study Says
4. Changes in the gut bacteria protect against stroke
5. Blau, Brown & Leonard, LLC Settlements Near Two Million Dollars on Behalf of Women who Endured DVT's, PE's and Strokes from Yaz, Yasmin and Ocella
6. Stress, Depression Linked to Raised Stroke Risk in Seniors
7. RSNA: New Study Finds Brain Angioplasty and Stents Safe and Effective for Stroke Patients
8. Study Supports Use of Brain Stents for Certain Stroke Patients
9. Flaxseed Can Reduce Risk of Stroke by 50% According to New Study Reviewed by the Project for Natural Health Choices Inc.
10. Brain angioplasty and stents found safe and effective for stroke patients
11. US Drug Watchdog Now Urges Women Who Used Yaz or Yasmin Birth Control Pills and Had a Heart Attack or Stroke to Call The Johnson Law Group immediately-Get Identified Now
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/17/2013)... (PRWEB) June 17, 2013 "Do you think ... are texting, emailing or using your phone even with a ... warns it is just as dangerous as not using a ... those of you using Facebook, texting, emailing etc." ... and alters their reflexes that distract the brain, according to ...
(Date:6/17/2013)... New York, NY (PRWEB) June 17, 2013 ... Block O'Toole & Murphy, LLP are pleased to ... http://www.blockotoole.com/Attorneys/Stephen-J-Murphy.shtml ) and David L. Scher ( http://www.blockotoole.com/Attorneys/David-L-Scher.shtml ... radio station Z100 (100.3 FM) this Sunday, June ... Mr. Scher will be guests on Kevin Burke's ...
(Date:6/17/2013)... According to a June 11, 2013 ABC News article, titled ... surfaces about the negative effects of sun on the ... skin care routine, as the sun's rays can ... “I agree with the article's suggestions for the best way ... Epione Beverly Hills. “Apply a minimum of SPF 30, twenty ...
(Date:6/17/2013)... As da Vinci robot lawsuit ... Bernstein Liebhard LLP notes that a recent report aired ... the disturbing robotic surgery complications alleged to have been caused ... the June 14th broadcast revealed that the U.S. Food & ... da Vinci patients who suffered burns, cuts and infections since ...
(Date:6/17/2013)... 17, 2013 San Antonio Eye Center PA has ... St. has just opened up a new portion of the office, ... downtown optical shop over the years, and SA Eye Center has ... Center one step closer to providing patients with everything they need ... The downtown optical shop is the largest SA Eye Center in ...
Breaking Medicine News(10 mins):Health News:Dr. Bonnie Weil Warns Hands Free is Not a Life Saver, It Can Be Just as Much of a Distraction 2Health News:Injury Attorneys Block O'Toole & Murphy, LLP to Appear on Z100 Radio Show This Sunday to Discuss Their Support of St. Jude Children's Research Hospital 2Health News:Skin Care – Answers to Your Sunscreen Questions 2Health News:Da Vinci Robot Lawsuit News: Bernstein Liebhard LLP Comments on NBC Report Detailing Robotic Surgery Complications 2Health News:Da Vinci Robot Lawsuit News: Bernstein Liebhard LLP Comments on NBC Report Detailing Robotic Surgery Complications 3Health News:San Antonio Eye Center PA Opens New Optical Shop 2
... Haiti , Jan. 19 One week later, ... of delivering aid in the aftermath of the Haiti ... aid is beginning to get through, the impact of the ... combined with a destroyed office and warehouse and the loss ...
... , JACKSONVILLE, Fla. and DES ... Inc. ( www.USPreventiveMedicine.com ) will partner with the Iowa Chronic Care ... not yet eligible for Medicare reduce health risks and live longer, ... equal amounts by a grant/cooperative agreement from the Centers for Disease ...
... PHILADELPHIA , Jan. 19 Independence Blue ... been promoted to chief marketing executive. Taylor will report to ... Independence Blue Cross. , As chief marketing executive, Taylor ... Cross (IBC) and two of the company,s third-party administrators:  Independence ...
... , , PHILADELPHIA , Jan. ... Paul A. Tufano has assumed an expanded role of senior ... continue to report to IBC president and CEO Joseph A. ... counsel since November 1999 when he joined IBC. , ...
... , ... Lindt Chocolate , the world,s leading producer of premium chocolate, announces it ... Autism program. For the second year, Lindt will honor ordinary individuals ... home or community.  The Lindt Unsung Heroes of Autism program is part ...
... Providence, RI New research at Rhode Island Hospital has ... brain tumors which, once diagnosed, offer a poor prognosis and ... naturally-occurring hormone combined with chemotherapy, researchers were able to inhibit ... study and their findings are published in the Journal ...
Cached Medicine News:Health News:Haiti Earthquake: One Week Later, Aid Agencies Facing Challenges 2Health News:Iowa Farm Bureau Introduces Bold Initiative to Improve Health Care for Rural Iowans 2Health News:Iowa Farm Bureau Introduces Bold Initiative to Improve Health Care for Rural Iowans 3Health News:Iowa Farm Bureau Introduces Bold Initiative to Improve Health Care for Rural Iowans 4Health News:Taylor Promoted to Independence Blue Cross Chief Marketing Executive 2Health News:Taylor Promoted to Independence Blue Cross Chief Marketing Executive 3Health News:Independence Blue Cross Announces New, Expanded Role For Key Executive 2Health News:Independence Blue Cross Announces New, Expanded Role For Key Executive 3Health News:Autism Speaks and Lindt Seeking Nominations for 'Lindt Unsung Heroes of Autism' 2Health News:Autism Speaks and Lindt Seeking Nominations for 'Lindt Unsung Heroes of Autism' 3Health News:Autism Speaks and Lindt Seeking Nominations for 'Lindt Unsung Heroes of Autism' 4Health News:Researchers find a treatment for deadly brain tumor 2
(Date:6/17/2013)... , June 17, 2013  A little known drug ... under scrutiny by the U.S. Supreme Court – and a ... issue could not have come at a better time for ... result from the Rx industry tactic are all too apparent ... of 50+ New Yorkers, state residents are in a near ...
(Date:6/17/2013)... PHILADELPHIA , June 17, 2013 ... support; program promoted through new ,Wake-Up Call, campaign ... Elsevier , a world-leading provider of scientific, technical ... the launch of EduCode ® Doc ... physicians and other practitioners. EduCode Doc Briefs is ...
(Date:6/17/2013)... , June 14, 2013 The law firm ... commenced what is believed to be the first suit in ... pancreatic cancer in the user of two common anti-diabetic drugs, ... Staten Island resident Robert Cataletto ... Pharmaceuticals, LLC, et al., E.D.N.Y. CV 13-3411. Mr. ...
Breaking Medicine Technology:Supreme Court Ruling on Rx Industry's Pay-to-Delay-Generics Good News for NY Consumers 2Supreme Court Ruling on Rx Industry's Pay-to-Delay-Generics Good News for NY Consumers 3Elsevier Launches EduCode Doc Briefs to Help Physicians Implement ICD-10 2Elsevier Launches EduCode Doc Briefs to Help Physicians Implement ICD-10 3Suit filed for Pancreatic Cancer By Use of Byetta, Januvia and Janumet 2
It provides cranial support in either supine or semi-sitting procedures....
Hudson cranial drill set which includes burr (9 mm), burr (14 mm), burr (16 mm), burr (22 mm), cerebellar extension, brace and sterilizing case....
Children's hospital hand drill, hexagonal handle, twist drill diameter 4.2 mm....
Hudson hand drill with extension piece....
Medicine Products: