Navigation Links
Silent stroke can cause Parkinson's disease
Date:12/18/2012

Scientists at The University of Manchester have for the first time identified why a patient who appears outwardly healthy may develop Parkinson's disease.

Whilst conditions such as a severe stroke have been linked to the disease, for many sufferers the tremors and other symptoms of Parkinson's disease can appear to come out of the blue. Researchers at the university's Faculty of Life Sciences have now discovered that a small stroke, also known as a silent stroke, can cause Parkinson's disease. Their findings have been published in the journal "Brain Behaviour and Immunity".

Unlike a severe stroke, a silent stroke can show no outward symptoms of having taken place. It happens when a blood vessel in the brain is blocked for only a very short amount of time and often a patient won't know they have suffered from one. However, it now appears one of the lasting effects of a silent stroke can be the death of dopaminergic neurons in the substantia nigra in the brain, which is an important region for movement coordination.

Dr. Emmanuel Pinteaux led the research: "At the moment we don't know why dopaminergic neurons start to die in the brain and therefore why people get Parkinson's disease. There have been suggestions that oxidative stress and aging are responsible. What we wanted to do in our study was to look at what happens in the brain away from the immediate area where a silent stroke has occurred and whether that could lead to damage that might result in Parkinson's disease."

The team induced a mild stroke similar to a silent stroke in the striatum area of the brain in mice. They found there was inflammation and brain damage in the striatum following the stroke, which they had expected. What the researchers didn't expect was the impact on another area of the brain, the substantia nigra. When they analysed the substantia nigra they recorded a rapid loss of Substance P (a key chemical involved in its functions) as well as in
'/>"/>

Contact: Morwenna Grills
Morwenna.Grills@manchester.ac.uk
44-161-275-2111
University of Manchester
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Neurocritical Care & Stroke Conference slated for March 2013
2. Telestroke networks can be cost-effective for hospitals, good for patients
3. High Blood Pressure Poses Bigger Stroke Risk for Blacks, Study Says
4. Changes in the gut bacteria protect against stroke
5. Blau, Brown & Leonard, LLC Settlements Near Two Million Dollars on Behalf of Women who Endured DVT's, PE's and Strokes from Yaz, Yasmin and Ocella
6. Stress, Depression Linked to Raised Stroke Risk in Seniors
7. RSNA: New Study Finds Brain Angioplasty and Stents Safe and Effective for Stroke Patients
8. Study Supports Use of Brain Stents for Certain Stroke Patients
9. Flaxseed Can Reduce Risk of Stroke by 50% According to New Study Reviewed by the Project for Natural Health Choices Inc.
10. Brain angioplasty and stents found safe and effective for stroke patients
11. US Drug Watchdog Now Urges Women Who Used Yaz or Yasmin Birth Control Pills and Had a Heart Attack or Stroke to Call The Johnson Law Group immediately-Get Identified Now
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... (PRWEB) July 14, 2014 Doctor Mike ... the launch of their new company website. The Inception ... free information on chiropractic marketing. It's also a place ... Inception has to offer. , When contacted at his ... newest version of our main website. Our site is ...
(Date:7/14/2014)... IL (PRWEB) July 14, 2014 ... marketing company for mental health professionals, announced today ... Association of North Carolina (LPCANC). This new ... online marketing solutions to LPCANC members, adding exclusive ... 7 years, we have been dedicated to providing ...
(Date:7/14/2014)... New York, NY (PRWEB) July 14, 2014 ... compatibility app on iTunes, called Love Digits. The App ... singles and couples alike to quantify their compatibility using ... times, and places, two people can instantaneously test their ... and Chinese astrology measures. , The app’s five-star rating ...
(Date:7/14/2014)... (PRWEB) July 14, 2014 EnergyFirst, ... and powder company Permalean for its great ... , Permalean, which markets its products as Jim’s ... now a part of EnergyFirst’s lineup of nutritional ... EnergyFirst over the coming year. , Founded in 1999, ...
(Date:7/14/2014)... Texas (PRWEB) July 14, 2014 ... forefront in complete spine care—from diagnosis to treatment and ... locations are either certified in or training for certification ... Theresa Adame, have recently completed the extensive program. , ... utilizing The McKenzie Method results in better outcomes for ...
Breaking Medicine News(10 mins):Health News:Doctor Mike Hamilton From Inception Chiropractic Websites Announces the Launch of Their New Website 2Health News:TherapySites Partners With the Licensed Professional Counselors Association of North Carolina to Make Online Marketing Available to All Therapists 2Health News:Love Digits, Numerical Approach to Modern Love, Now Available on iTunes 2Health News:Love Digits, Numerical Approach to Modern Love, Now Available on iTunes 3Health News:EnergyFirst Acquires Permalean - Manufacturer of All Natural Protein Bars and Powders 2Health News:EnergyFirst Acquires Permalean - Manufacturer of All Natural Protein Bars and Powders 3Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 2Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 3
... 11 (HealthDay News) -- Parkinson,s disease patients who receive care ... break a hip or need nursing-home placement than those treated ... American researchers looked at the medical records of all ... Between that time and 2005, 68 percent of the patients ...
... drugs as a first-line treatment for people with tuberculosis (TB) ... not been well understood. Now, researchers have discovered a key ... TB therapy. The finding potentially paves the way for the ... an infected individual even more rapidly. The study was supported ...
... THURSDAY, Aug. 11 (HealthDay News) -- What do a ... A lot more than you might expect, new research ... aquatic reptile with its embryo offers the first evidence ... that they may have had a social structure similar ...
... August 11, 2011) According to a study ... the American Society of Hematology (ASH), researchers have ... that releases stem cells from the bone marrow into the ... risk for later development of abnormalities involving loss or gains ...
... , THURSDAY, Aug. 11 (HealthDay News) -- American women ... those born in 1910 or 1960, according to researchers who analyzed ... 1935 had an average of three children per woman, compared with ... for those born in 1960, their study found. Of the ...
... 11 (HealthDay News) -- Like humans, chimpanzees are born ... to track the development of three chimpanzees, brains from ... areas of the brain that play an important role ... and creativity are immature in both chimps and humans, ...
Cached Medicine News:Health News:Parkinson's Patients May Fare Better in Neurologist's Care 2Health News:Prehistoric Water Reptile's Social Life Similar to Dolphins: Study 2Health News:Stem cell mobilization therapy found to be safe for bone marrow donors 2Health News:Stem cell mobilization therapy found to be safe for bone marrow donors 3Health News:Women Born After Great Depression Had More Children, Study Finds 2
(Date:7/13/2014)... July 13, 2014 ... Tokio veranstalteten F&E-Tagung meldete ... zur Neuausrichtung seines Forschungsrahmenprogramms. Die Tagung bot ... die fortgeschrittenen klinischen Programme und die Konzernstrategie ... Tagung bestand darin, aktuelle Meldungen zu den ...
(Date:7/13/2014)... 2014  Eli Lilly and Company (NYSE: ... non-clinical study in genetically engineered mice examining combination ... antibody N3pG and beta-secretase inhibitor BACE (LY2811376). Data ... in removing clumps of amyloid-beta protein in the ... lead to Alzheimer,s disease (AD) – than use ...
(Date:7/11/2014)... 11, 2014 /PRNewswire-iReach/ -- VAPETEK™, Inc. has announced ... for use in portable vaporizers, which contains CBD, ... in cannabis, cannabidiol offers consumers a THC-free product ... other vaporizer technology. Photo - ... 483 different compounds which are currently known, two ...
Breaking Medicine Technology:Astellas erörtert Pipeline-Fortschritte auf F&E-Tagung 2Astellas erörtert Pipeline-Fortschritte auf F&E-Tagung 3Astellas erörtert Pipeline-Fortschritte auf F&E-Tagung 4New Data Shows Combination Therapy is More Effective than Monotherapy in Removing Beta-Amyloid Plaques from the Brains of Mice 2New Data Shows Combination Therapy is More Effective than Monotherapy in Removing Beta-Amyloid Plaques from the Brains of Mice 3VAPETEK Releases CBD-Infused eLiquid For The Consumer Market 2
... strategic transaction processSAN DIEGO, May 7 ADVENTRX ... today announced results from its bioequivalence study of ... have comparable overall safety as Taxotere(R), the reference ... severe toxicities. However, pharmacokinetic equivalence, the primary ...
... is to Enhance Patient Safety and Reduce Health Care ... will join in a pilot program, contributing data on ... the data collected, it will be possible to identify ... patient safety while reducing overall costs to the health ...
Cached Medicine Technology:ADVENTRX Announces Results From ANX-514 Bioequivalence Study 2ADVENTRX Announces Results From ANX-514 Bioequivalence Study 3ADVENTRX Announces Results From ANX-514 Bioequivalence Study 4ADVENTRX Announces Results From ANX-514 Bioequivalence Study 5National Hemovigilance Pilot Program Launches to Track Adverse Events Associated with Blood Transfusion 2National Hemovigilance Pilot Program Launches to Track Adverse Events Associated with Blood Transfusion 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: