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Sickle Cell Disease Tied to 'Silent Strokes' in Children
Date:12/2/2011

who have early signs of anemia and high blood pressure, both of which are modifiable risk factors. The findings may also lead to new treatments for sickle cell disease.

The study was published online Nov. 17 in the journal Blood.

While extremely rare in children overall, stroke is a common complication in children with sickle cell disease. Nearly 100,000 people in the United States have sickle cell disease. The disease, inherited from both parents, causes red blood cells to take the shape of crescents or sickles, and results in less oxygen being delivered to the body's tissues. These fragile cells can interrupt blood flow when they get stuck in small blood vessels. Patients with sickle cell disease require ongoing treatment, according to the U.S. National Institutes of Health, which funded the study.

More information

The Nemours Foundation has more about sickle cell disease.

-- Robert Preidt

SOURCE: Johns Hopkins Children's Center, news release, Nov. 28, 2011


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