Navigation Links
Should intra-abdominal pressure measurement be a routine for all pancreatitis patients?
Date:2/19/2009

Acute pancreatitis remains a disease with an unpredictable clinical course, and significant associated morbidity and mortality. Recently, the elevated intraabdominal pressure (IAP) after onset of acute pancreatitis has gained growing attention, because it is increasingly recognized as an important risk factor for mortality in the early phase of the disease. However, It is still not clear whether early intra-abdominal pressure measurement should be a routine for all acute pancreatitis patients and which patients would benefit most from the IAP monitoring.

A research team led by Dr. Zilvinas Dambrauskas from Lithuania addressed this question. Their study will be published on February 14, 2009 in the World Journal of Gastroenterology.

In their study, Patients (n = 44) with AP recruited in this study were divided into two groups (ACS and non-ACS) according to intra-abdominal pressure (IAP) determined by indirect measurement using the transvesical route via Foley bladder catheter. On admission and at regular intervals the severity of the AP and presence of organ dysfunction were assessed utilizing different multifactorial prognostic systems: Glasgow-Imrie score, Acute Physiology and Chronic Health Evaluation Ⅱ (APACHE-Ⅱ) score, and Multiorgan Dysfunction Score (MODS). The diagnostic performance of scores predicting ACS development, cut-off values and specificity and sensitivity were established using Receiver Operating Characteristic (ROC) curve analysis.

They found that the incidence of ACS in our study population was 19.35%. IAP at admission of ACS group was 22.0 (18.5-25.0) mmHg and 9.25 (3.0-12.4) mmHg in non-ACS group (P < 0.01). Univariate statistical analysis revealed that patients in ACS group had significantly higher multifactorial clinical scores (APACHE Ⅱ, Glasgow-Imrie and MODS) on admission and higher maximal scores during hospitalization (P < 0.01). ROC curve analysis revealed that APACHE Ⅱ, Glasgow-Imrie, and MODS are valuable tools for early prediction of ACS with high sensitivity and specificity, and that cutoff values are similar to those used for stratification of patients with severe acute pancreatitis (SAP).

They concluded that IAH and ACS are rare findings in patients with mild AP and they recommend measuring the IAP in cases when patients present with SAP (APACHE Ⅱ > 7; MODS > 2 or Glasgow-Imrie score > 3).


'/>"/>

Contact: Lai-Fu Li
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Related medicine news :

1. National Pharmaceutical Council on Economic Stimulus Package: Comparative Effectiveness Research Funding Should Target Improvements in Quality of Patient Care
2. Force Tester Shoulders The Burden
3. Contact Lens Wearers Should Blink More Often During Winter - Tips from VisionDirect.com to Keep Eyes Moist During Dry Winter Months
4. Virginia Leaders Should Reject Flawed Smoke-Free Legislation That Fails to Protect Everyones Right to Breathe Clean Air
5. Alternative and complementary medicine should have role in new era of health care reform
6. Alternative and Complementary Medicine Should Have Role in New Era of Health Care Reform
7. Pictures Say a Thousand Words... No American Should Lack Access to Affordable, Comprehensive Health Services
8. Three-Quarters of Americans Believe Health Insurance Should Pay for Addiction Treatment, Yet Most Dont Know If Their Health Plan Covers Substance-Abuse Care, Says New Hazelden Survey
9. Quick Orthopedic Repair Can Save Young Shoulders
10. Immediate Orthopaedic Care Can Help Heal a Young Athletes Shoulder
11. HS Sports Shoulder Injuries More Likely in Boys
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... , ... October 13, 2017 , ... ... throughout Arkansas that offers insurance and financial preparation services, is providing an update ... City Rescue organization. , Rock City Rescue is a locally recognized nonprofit that ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... established the certification process to promote standards of excellence for the field of ... scheduled for March 22 – 25, 2018 in Orlando, Florida at the Omni ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes ... a mock evacuation of the facility as part of a disaster drill on October ... Hose EMS and Shelton City Emergency Manager, as well as the Connecticut Long ...
(Date:10/13/2017)... ... ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many kids ... sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids excited ... all ages; it is a non-competitive, non-timed event, which is all about having fun ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to ... to save lost souls in the Philippines. “The Journey: From the Mountains to the ... teacher of the Bible. She has taught all ages and currently teaches a class ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... COUNTY, Calif. , Oct. 10, 2017  NDS received FDA ... Mobile  — a medical-grade battery-powered display stand specifically designed for endoscopy ... to transform technology into a clinical solution to support the improvement ... Innovative Design ... ZeroWire Mobile Wireless Solution ...
(Date:10/5/2017)... , Oct. 5, 2017  In response to ... Oral and Maxillofacial Surgeons (AAOMS) released prescribing recommendations ... to be used as a first-line therapy to ... Recognizing the value ... White Paper "Opioid Prescribing: Acute and Postoperative Pain ...
(Date:10/4/2017)... OBP Medical , a leading ... today announced regulatory approval from Brazil,s ... Nacional de Vigilância Sanitária (ANVISA)) to market ... with integrated LED light source and smoke evacuation ... of a tissue pocket or cavity during surgical ...
Breaking Medicine Technology: