Navigation Links
Should intra-abdominal pressure measurement be a routine for all pancreatitis patients?
Date:2/19/2009

Acute pancreatitis remains a disease with an unpredictable clinical course, and significant associated morbidity and mortality. Recently, the elevated intraabdominal pressure (IAP) after onset of acute pancreatitis has gained growing attention, because it is increasingly recognized as an important risk factor for mortality in the early phase of the disease. However, It is still not clear whether early intra-abdominal pressure measurement should be a routine for all acute pancreatitis patients and which patients would benefit most from the IAP monitoring.

A research team led by Dr. Zilvinas Dambrauskas from Lithuania addressed this question. Their study will be published on February 14, 2009 in the World Journal of Gastroenterology.

In their study, Patients (n = 44) with AP recruited in this study were divided into two groups (ACS and non-ACS) according to intra-abdominal pressure (IAP) determined by indirect measurement using the transvesical route via Foley bladder catheter. On admission and at regular intervals the severity of the AP and presence of organ dysfunction were assessed utilizing different multifactorial prognostic systems: Glasgow-Imrie score, Acute Physiology and Chronic Health Evaluation Ⅱ (APACHE-Ⅱ) score, and Multiorgan Dysfunction Score (MODS). The diagnostic performance of scores predicting ACS development, cut-off values and specificity and sensitivity were established using Receiver Operating Characteristic (ROC) curve analysis.

They found that the incidence of ACS in our study population was 19.35%. IAP at admission of ACS group was 22.0 (18.5-25.0) mmHg and 9.25 (3.0-12.4) mmHg in non-ACS group (P < 0.01). Univariate statistical analysis revealed that patients in ACS group had significantly higher multifactorial clinical scores (APACHE Ⅱ, Glasgow-Imrie and MODS) on admission and higher maximal scores during hospitalization (P < 0.01). ROC curve analysis revealed that APACHE Ⅱ, Glasgow-Imrie, and MODS are valuable tools for early prediction of ACS with high sensitivity and specificity, and that cutoff values are similar to those used for stratification of patients with severe acute pancreatitis (SAP).

They concluded that IAH and ACS are rare findings in patients with mild AP and they recommend measuring the IAP in cases when patients present with SAP (APACHE Ⅱ > 7; MODS > 2 or Glasgow-Imrie score > 3).


'/>"/>

Contact: Lai-Fu Li
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Related medicine news :

1. National Pharmaceutical Council on Economic Stimulus Package: Comparative Effectiveness Research Funding Should Target Improvements in Quality of Patient Care
2. Force Tester Shoulders The Burden
3. Contact Lens Wearers Should Blink More Often During Winter - Tips from VisionDirect.com to Keep Eyes Moist During Dry Winter Months
4. Virginia Leaders Should Reject Flawed Smoke-Free Legislation That Fails to Protect Everyones Right to Breathe Clean Air
5. Alternative and complementary medicine should have role in new era of health care reform
6. Alternative and Complementary Medicine Should Have Role in New Era of Health Care Reform
7. Pictures Say a Thousand Words... No American Should Lack Access to Affordable, Comprehensive Health Services
8. Three-Quarters of Americans Believe Health Insurance Should Pay for Addiction Treatment, Yet Most Dont Know If Their Health Plan Covers Substance-Abuse Care, Says New Hazelden Survey
9. Quick Orthopedic Repair Can Save Young Shoulders
10. Immediate Orthopaedic Care Can Help Heal a Young Athletes Shoulder
11. HS Sports Shoulder Injuries More Likely in Boys
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... ... March 28, 2017 , ... Award-winning medical group Allied ... as new board chair for Orange County health care system CalOptima Friday. CalOptima ... soon-to-be former chair Mark Refowitz’s term, which runs through June 30 of this ...
(Date:3/28/2017)... MA (PRWEB) , ... March 28, 2017 , ... ... for direct measurement of corrosive ions found in power plant water and steam. ... components such as turbines and boilers, leading to extensive maintenance and unplanned shutdowns. ...
(Date:3/28/2017)... ... 2017 , ... A minimally invasive porcelain veneer is increasing ... Association of Dental Laboratories (NADL) is informing dentists about the benefits of minimally ... dental laboratories and technicians that create these veneers. , According to National ...
(Date:3/28/2017)... ... March 28, 2017 , ... The Lice Treatment Center® ... March 13-16, was a busy spot this year. Liz Solovay and Adrian Picheny, ... preventing outbreaks among camp communities during the upcoming 2017 camping season. “Lice infestations ...
(Date:3/28/2017)... ... , ... Thank you to all who attended Capio Partners Winter 2017 Healthcare ... exclusive to providers and offered an opportunity to collaborate and network with healthcare colleagues ... Hyatt where attendees gathered for a lively discussion on trends and issues that healthcare ...
Breaking Medicine News(10 mins):
(Date:3/28/2017)... ROCKVILLE, Md. , March 28, 2017 /PRNewswire/ ... dedicated to innovative therapeutics addressing cancer and other ... at the American Association for Cancer Research annual ... April 3 is entitled "Evaluation of ENMD-2076 ... and the second poster to be presented ...
(Date:3/28/2017)... Elysium Health joins major pharmaceutical ... Cambridge academic scientists through ... Milner Therapeutics Institute today announces Elysium Health as a partner ... investment for collaborative projects with academic researchers in ... the first major research investment outside the U.S. for the ...
(Date:3/27/2017)... WAUKESHA, Wis. , March 27, 2017  A ... one of only four freestanding hospitals in the country ... in plastic and reconstructive surgery, concluded that the Surfacide ... effective and integral component in reducing bacterial pathogens not ... The findings were published at the American Burn Association,s ...
Breaking Medicine Technology: