Navigation Links
Short nanotubes target pancreatic cancer
Date:6/5/2014

Short, customized carbon nanotubes have the potential to deliver drugs to pancreatic cancer cells and destroy them from within, according to researchers at Rice University and the University of Texas MD Anderson Cancer Center.

Pristine nanotubes produced through a new process developed at Rice can be modified to carry drugs to tumors through gaps in blood-vessel walls that larger particles cannot fit through.

The nanotubes may then target and infiltrate the cancerous cells' nuclei, where the drugs can be released through sonication that is, by shaking them.

The research led by Rice chemist Andrew Barron was reported in the Royal Society of Chemistry's Journal of Materials Chemistry B.

Most pancreatic cancer patients die within a year of diagnosis and have a five-year survival rate of 6 percent, partially because there is no method for early detection, according to the American Cancer Society. Tumors are often inoperable and pancreatic cancer cells are also difficult to reach with chemotherapy, said co-author Jason Fleming, a professor of surgical oncology at MD Anderson.

"These findings are encouraging because they offer a potential delivery solution for pancreatic cancer patients whose tumors resist standard chemotherapy," Fleming said. "There are molecular and biological barriers to efficient delivery of chemotherapy to pancreatic cancer tumors, and these nanotubes might be able to make some of those irrelevant."

Rice scientists made nanotubes pure enough to modify for the purpose and small enough to squeeze through the body's defenses, Barron said. The researchers knew from previous work that nanotubes could be modified a process called functionalization to carry chemotherapy agents and release them at a controlled rate through sonication.

"This time, we were trying to work out how long the tubes should be and the extent of functionalization to maximize uptake by the cells," Barron
'/>"/>

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Scripps Florida scientists unravel the molecular secret of short, intense workouts
2. Shorter TB treatment regimens will reduce cost for patients and their families
3. Addressing the physician shortage: Recommendations for medical education reform
4. Women repeatedly short-changed in case of premature ejaculation
5. Women with unintended pregnancies take the shortest maternity leaves
6. Loss of Y chromosome can explain shorter life expectancy and higher cancer risk for men
7. Food shortages could be most critical world issue by mid-century
8. Short circuit in molecular switch intensifies pain
9. Introducing a New Sand Wedge that Is Perfect for Taking Strokes off the Short Game, Courtesy of Black Magic’s Innovative Golf Wedge
10. Black Magic’s Advanced Engineering With Golf Equipment for the Short Game Offers a Top of the Line Gap Wedge That Can Have You Shooting Lower Scores in No Time
11. New Collection Of Short Wedding Dresses Available At FannyBrides.com
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Short nanotubes target pancreatic cancer
(Date:8/21/2014)... CA (PRWEB) August 21, 2014 Sleep Apnea ... across the U.S. This provides doctors with a convenient way ... find a doctor are that much closer to finding ... have no idea they are experiencing this sleep disorder ... receive treatment at all. , Thanks to Sleep Apnea Doctors ...
(Date:8/21/2014)... Cary, NC (PRWEB) August 21, 2014 ... solutions for the health and human services markets, announced ... features and capabilities incorporating the Tin Can API. ... and their employees have the most advanced mobile learning ... greatest in adult learning tools and techniques,” says Jim ...
(Date:8/21/2014)... ERT, a leading global solution ... endpoint data collection, today opened registration for ... Product Value with Optimized Endpoints. The ... developers to network with leading researchers as ... implementing, and justifying effective strategies for collecting ...
(Date:8/21/2014)... elicited by T-type calcium channels in the thalamic ... of calcium. These channels enable thalamic reticular nucleus ... to enter a hyper-excited state. , In order ... absence seizures, the researchers conducted an experiment to ... techniques to delete the T-type calcium channel CaV3.3. ...
(Date:8/21/2014)... Do we drive to work or take the train? From ... make hundreds of different decisions every day. Even if these ... for our long-term personal development to make decisions that are ... difficult, however. They are known to make impulsive decisions, often ... of making a choice that yields a greater reward later ...
Breaking Medicine News(10 mins):Health News:Sleep Apnea Doctors US is Now Offering Complimentary Listings to Sleep Apnea Doctors Across the United States 2Health News:Relias Learning Announces Support for Tin Can API 2Health News:ERT Opens Registration for PROFICIENCY™ Regional Conference Series 2Health News:ERT Opens Registration for PROFICIENCY™ Regional Conference Series 3Health News:ADHD children make poor decisions due to less differentiated learning processes 2
... SOUTH SAN FRANCISCO, Calif., July 29 Poniard Pharmaceuticals, Inc. ... innovative oncology therapies, today announced that Jerry McMahon, Ph.D., chairman ... overview, including a discussion about the clinical development program for ... conferences: , , , ...
... , SAN DIEGO, July 29, 2009 Arena ... will report second quarter 2009 financial results after the NASDAQ ... afternoon, Jack Lief, Arena,s President and Chief Executive Officer, and ... Officer, will host a conference call at 5:00 p.m. Eastern ...
... , JACKSONVILLE, Fla., July 29 Today, Wounded ... bill (H.R. 3155) that will assist the family caregivers of ... (S. 801) that would provide more comprehensive support and coverage ... need of these services. H.R. 3155, the Caregiver Assistance and ...
... SAN FRANCISCO, July 29 Medivation, Inc. (Nasdaq: ... and webcast with management to discuss second quarter 2009 financial results ... at 4:30 p.m. Eastern Time. A press release for the second ... on August 5, 2009. , , Interested parties ...
... , , , , ... Carefx Corporation , a leading provider of interoperable workflow ... that one of its clients, the Louisiana Rural Health Information Exchange (LARHIX), ... Health Information Executives , a top healthcare information technology magazine. ...
... , , MONROVIA, ... ), a leading developer, manufacturer and marketer of minimally invasive ophthalmic ... Officer will present at the BMO Capital Markets 9th Annual Focus ... 5th at 4:00 pm Eastern Time. , , ...
Cached Medicine News:Health News:Poniard Pharmaceuticals to Present at Two Upcoming Investor Conferences in August 2Health News:Arena Pharmaceuticals to Host Business and Financial Update Conference Call and Webcast on Monday, August 3, 2009 2Health News:Arena Pharmaceuticals to Host Business and Financial Update Conference Call and Webcast on Monday, August 3, 2009 3Health News:Wounded Warrior Project (WWP) Pushes for Senate Bill to Assist Family Caregivers of the Most Severely Injured Veterans 2Health News:Medivation Announces Second Quarter 2009 Financial Results Teleconference and Webcast on August 5, 2009 2Health News:Top Healthcare Magazine Awards Carefx Client '2009 IT Project of the Year' 2Health News:Top Healthcare Magazine Awards Carefx Client '2009 IT Project of the Year' 3
(Date:8/21/2014)... Aug. 21, 2014  Decision Resources Group finds ... Brazil and ... and commonly prescribe long-acting beta-agonist (LABA)- and long-acting ... so within current severe cost/coverage constraints. Therefore, new ... expected to launch in these countries—which will considerably ...
(Date:8/21/2014)... , Aug. 21, 2014  Seventy-one percent of Americans ... OxyContin is a serious public health and safety issue in ... from a survey released today by Repass & Partners, a ... "Americans understand the severity of the prescription medication ... progress with this very serious health situation facing our country," ...
(Date:8/21/2014)... Aug. 21, 2014  Henry Schein, Inc. (NASDAQ: ... and services to office-based dental, animal health and medical practitioners, ... conferences in September: , September 4, 2014 – ... , NY at 12:50 p.m. ET , September 8, 2014 ... New York , NY at 1:25 p.m. ET ...
Breaking Medicine Technology:Novel Fixed-Dose Combinations for COPD in Brazil and Mexico Will Compete With Well-Established Therapies in an Environment Dominated by Aggressive Cost-Control Mechanisms 2Novel Fixed-Dose Combinations for COPD in Brazil and Mexico Will Compete With Well-Established Therapies in an Environment Dominated by Aggressive Cost-Control Mechanisms 3Consumers Desperate For Measures To Curb Prescription Drug Abuse 2Consumers Desperate For Measures To Curb Prescription Drug Abuse 3Henry Schein To Present At Two Investor Conferences In September 2
... 4, 2011 /PRNewswire-Asia-FirstCall/ -- Dehaier Medical Systems Ltd. ... "Company"), an emerging leader in the development, assembly, marketing ... in China, today announced that it will release financial ... June 30, 2011 on Monday, August 15, 2011 before ...
... Medical, Inc. (OTCBB: HASC), www.mysouthernmed.com , a ... Florida, and Mississippi, announced today that the Chairman ... guaranteed the financing that was used for the ... on May 17th, 2011. As part ...
Cached Medicine Technology:Dehaier Medical to Report Second Quarter 2011 Financial Results on August 15 2HASCO Medical Chairman Provides $2 Million in Capital and a Personal Guarantee on Additional $2 Million Promissory Note 2HASCO Medical Chairman Provides $2 Million in Capital and a Personal Guarantee on Additional $2 Million Promissory Note 3
... to U.S. and international engineering and ... Screw and Plating System* provides seamless ... of use for open reduction internal ... TC-100 system works well beyond the ...
... The Alphatec Small Fragment ... wide range of fractures, including ... distal humerus, distal radius, distal ... malleolus, metatarsals, and metacarpals. The ...
Stainless steel threaded Steinman Pins available in point types A,D, E, and F....
Round Bevel-Point Pin Sets available in 2.3mm, 3.1mm, 4.7mm, and 6.3mm sizes....
Medicine Products: