Navigation Links
Short-Term Air Pollution Exposure May Damage DNA
Date:5/17/2009

Gene reprogramming can occur in just 3 days time

SUNDAY, May 17 (HealthDay News) -- Breathing polluted air for even a short period of time can cause some genes to undergo reprogramming, which may affect a person's risk of developing cancer and other diseases, say Italian researchers.

Comparisons of blood DNA samples from healthy workers who were exposed to high levels of airborne particulates at a foundry near Milan revealed that after only three days of exposure, changes occurred in four genes that have been linked to tumor suppression, according to research presented Sunday at the International Conference of the American Thoracic Society, in San Diego.

This finding indicates "that environmental factors need little time to cause gene reprogramming, which is potentially associated with disease outcomes," investigator Dr. Andrea Baccarelli, assistant professor of applied biotechnology at the University of Milan, said in a news release issued by the conference's sponsor.

"As several of the effects of particulate matter in foundries are similar to those found after exposure to ambient air pollution, our results open new hypotheses about how air pollutants modify human health," Baccarelli said.

The changes in the foundry workers' genes may have been caused by DNA methylation, a chemical transformation process that has been linked to gene reprogramming and has been found in the blood and tissue samples of lung cancer patients, Baccarelli noted.

"The changes in DNA methylation we observed are reversible, and some of them are currently being used as targets of cancer drugs," said the researcher, who added that it might be possible to design early interventions that could program that gene back to normal and mitigate the increased health risks of air pollutants.

"We need to evaluate how the changes in gene reprogramming we observed are related to cancer risk," Baccarelli said.

<
'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Chem Rx Corporation Enters Short-Term Forbearance Agreements With Lenders
2. Decoding short-term memory with fMRI
3. Assessing the real risk of heart disease in young people with low short-term risks
4. New data show patients using avonex reported less sick leave and short-term disability costs
5. Short-term use of antipsychotics in older adults with dementia linked to serious adverse events
6. FDA Approves NEXIUM(R) for the Treatment of Short-Term GERD in Children 1 to 11 Years Old
7. Journal Sleep: A short-term dose of zolpidem is an effective treatment for insomnia
8. The Westaim Corporation update on status of short-term investments
9. Short-term hemofiltration is cost-effective for severe acute pancreatitis
10. Physiotherapy has short-term benefits for patients after knee surgery
11. Air Pollution Exposure May Slow Fetal Growth
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Short-Term Air Pollution Exposure May Damage DNA
(Date:8/21/2014)... DMG Productions announces the upcoming airing of Innovations ... August 25, 2014 at 7:00 a.m. EST and 7:00 ... episode, Innovations will go behind-the-scenes to demonstrate how Freenotes ... Audiences will be amazed by the park's that focus ... providing access to real musical instruments. , Audiences will ...
(Date:8/21/2014)... August 21, 2014 Being overweight or ... painful osteoarthritis. Although there is no cure, patients have ... making certain lifestyle changes, such as losing excess weight ... , Osteoarthritis is a joint disorder which causes discomfort ... and neck and can significantly reduce one’s quality of ...
(Date:8/21/2014)... Australian scientists say a commercially available compound ... used to successfully fight mesothelioma in lab mice. Surviving ... research. Click here to read it now. ... mesothelioma cells with the S. aureus mixture ... simultaneously stimulating a stronger anti-tumor response in healthy cells. ...
(Date:8/21/2014)... Louis, MO (PRWEB) August 21, 2014 ... wellness in all aspects of life, St. Louis’ Sound ... for the better and revolutionized its online presence. Reorganized ... Mind Café, the new website makes navigating for information ... blue and an easily accessible menu-bar in jet black, ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 Bunion Bootie ... Pedorthics, a bi-monthly publication of the Pedorthic Footcare Association and ... , Bunion Bootie is a new ... for bunion sufferers and their pain. It is extremely comfortable ... any shoe to eliminate the friction and rubbing of shoes ...
Breaking Medicine News(10 mins):Health News:Announcing New Episode Airing of Innovations on Monday August 25, 2014 via Discovery Channel 2Health News:Diet Doc’s Medical Weight Loss Programs Announces Safe and Fast Weight Loss That Teach Patients How to Relieve Osteoarthritis Pain 2Health News:Diet Doc’s Medical Weight Loss Programs Announces Safe and Fast Weight Loss That Teach Patients How to Relieve Osteoarthritis Pain 3Health News:Study Finds Bacteria Compound Shrinks Mesothelioma Tumors, According to Surviving Mesothelioma 2Health News:Sound Mind Cafe Launches Revamped Website and Hires Hypnotist to Team 2Health News:Recently Featured in Current Pedorthics: Bunion Bootie, the Very Popular Bunion Treatment Splint 2Health News:Recently Featured in Current Pedorthics: Bunion Bootie, the Very Popular Bunion Treatment Splint 3
... , WASHINGTON, July 30 An estimated ... if Congress passes a House health reform bill, according to ... 2009 released this week by The Heritage ... The Lewin Group , a highly respected health ...
... , , WASHINGTON, July 30 ... today launched new tools and services designed to help independent retail ... communities. , , With a conference theme of ... the nation,s capitol to underscore its continued commitment to creating successful, ...
... to an evolutionary event , THURSDAY, July 30 (HealthDay ... distinctively short legs following a single change to the ... that may also help explain a type of human ... Institute (NHGRI) found that about 20 short-legged dog breeds, ...
... , - New NMA President to Address Health ... LAS VEGAS, July 30 Delivering her inaugural address as ... Edwards, MD, MBA, shared her plans to focus on health care ... nation,s premier organization for African American physicians. , , ...
... July 30 Human pheromones are over-stated, or are they? ... to whether or not human pheromones exist, and, if they do, exactly ... the lay community, pheromones are thought of as sexual ... the research and education division of The Fragrance Foundation, turned to ...
... from sunlight may be associated with the development of ... study by researchers at the National Institute of Environmental ... Health. "This study found that women who lived ... they developed an autoimmune muscle disease called myositis were ...
Cached Medicine News:Health News:Millions of Virginians Could Lose Private Insurance, Study Shows 2Health News:Cardinal Health Welcomes Record Number of Attendees at its Annual Independent Pharmacy Trade Show 2Health News:Cardinal Health Welcomes Record Number of Attendees at its Annual Independent Pharmacy Trade Show 3Health News:Cardinal Health Welcomes Record Number of Attendees at its Annual Independent Pharmacy Trade Show 4Health News:Researchers Discover the Tale Behind Short Dogs 2Health News:National Medical Association Installs 110th President at Las Vegas Convention 2Health News:Sun exposure may trigger certain autoimmune diseases in women 2
(Date:8/21/2014)... 2014   Royal Philips (NYSE: ... has received 510(k) clearance from the U.S. Food ... application for Transcatheter Aortic-Valve Implantation (TAVI) treatments. Through ... with pre-procedural, high-precision positioning to treat aortic stenosis ... is available as part of Philips IntelliSpace ...
(Date:8/21/2014)... CYBX ) today announced results for the quarter ...   Operating results for the first quarter of ... and other achievements, include: , Worldwide net product sales ... international net sales of $13.2 million, an increase of 14.5% ... sales reached a new high of $58.8 million, an increase ...
(Date:8/21/2014)... 2014  SI-BONE, Inc. ( San Jose, California ... use of the iFuse Implant System, ® a ... the sacroiliac (SI) joint, announced that Priority Health ( ... Lumbar Fusion Medical Policy No. 91590-R4 providing positive coverage ... states that the fusion procedure, which employs the iFuse ...
Breaking Medicine Technology:Philips receives FDA 510(k) Clearance for TAVI Precision Treatment Planning Application 2Philips receives FDA 510(k) Clearance for TAVI Precision Treatment Planning Application 3Cyberonics Reports Fiscal 2015 First Quarter Results 2Cyberonics Reports Fiscal 2015 First Quarter Results 3Cyberonics Reports Fiscal 2015 First Quarter Results 4Cyberonics Reports Fiscal 2015 First Quarter Results 5Cyberonics Reports Fiscal 2015 First Quarter Results 6Cyberonics Reports Fiscal 2015 First Quarter Results 7Cyberonics Reports Fiscal 2015 First Quarter Results 8Cyberonics Reports Fiscal 2015 First Quarter Results 9Cyberonics Reports Fiscal 2015 First Quarter Results 10Cyberonics Reports Fiscal 2015 First Quarter Results 11Cyberonics Reports Fiscal 2015 First Quarter Results 12Cyberonics Reports Fiscal 2015 First Quarter Results 13Cyberonics Reports Fiscal 2015 First Quarter Results 14Cyberonics Reports Fiscal 2015 First Quarter Results 15Cyberonics Reports Fiscal 2015 First Quarter Results 16SI-BONE, Inc. Announces Positive Coverage Decision by Priority Health 2SI-BONE, Inc. Announces Positive Coverage Decision by Priority Health 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: