Navigation Links
Shire reports analysis examining emotional lability in children with ADHD taking Vyvanse
Date:11/13/2009

t hoc analysis, the children's emotional lability score was determined based on the sum of their average scores from three items on the CPRS-RS: angry/resentful, loses temper, and irritable. Patients were then grouped into those with and without prominent emotional lability at study start (scores greater than three versus scores of three or less) so that each group could be evaluated separately.

Overall, the children's average emotional lability scores significantly improved with Vyvanse treatment compared with placebo across the day (10 AM, 2 PM, and 6 PM) from study start to end (all P≤.0004).

As expected, treatment with Vyvanse, compared to placebo, did not result in significant improvements in emotional lability scores from study start to end in those without prominent emotional lability prior to treatment. However, treatment with Vyvanse, compared to placebo, yielded significant improvements in the emotional lability scores of those children with prominent emotional lability (P<.0001).

The most common treatment-emergent adverse events reported in this study for patients taking Vyvanse were decreased appetite, insomnia, upper abdominal pain, headache, irritability, vomiting, weight decrease, nausea, dizziness, and dry mouth.

Vyvanse, which was introduced in the United States in July 2007 for the treatment of ADHD in children aged 6 to 12 years and approved in April 2008 to treat ADHD in adults, is currently available in six dosage strengths of 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, and 70 mg.

Vyvanse is a therapeutically inactive prodrug stimulant, in which d-amphetamine is covalently bonded to l-lysine, and after oral ingestion it is converted to pharmacologically active d-amphetamine. The conversion of Vyvanse to d-amphetamine is not affected by gastrointestinal pH and is unlikely to be affected by alterations in GI transit times.


'/>"/>

Contact: Matt Cabrey
mcabrey@shire.com
484-595-8248
Porter Novelli
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Exciting New Plan from John Edwards on AIDS; Plan is Bold and Achievable, say New Hampshire Activists
2. URAC CEO Testifies Before New Hampshire Legislators Regarding New URAC Standards for Pharmacy Benefit Management
3. Families Invited to Celebrate Shire Day at Boston Childrens Museum
4. New Hampshire: 1st in the Nation Primary State Takes a Stand on E-Prescribing
5. Shire to Present New Scientific Data on its ADHD Treatments at a Major Psychiatric Meeting
6. New Hampshire AIDS Group Calls on Huckabee to Disavow His 1992 Statement
7. VIDEO from Medialink and Shire plc: Rare Diseases Must Be Top of the Health Agenda
8. Shire Launches Patient Education Forums on Better Managing the Challenges of Ulcerative Colitis
9. AUDIO from Medialink and Shire: What It Means to be an Adult With ADHD
10. Shire to present ADHD treatments scientific data at American Psychiatric Assoc. Meeting
11. Anthem Blue Cross and Blue Shield in New Hampshire Announces Unique Enhancement to its ePrescribing Program
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/12/2014)... 2014 A recent article released by Seattle's ... of suggestions for those seeking cosmetic surgical procedures in ... approaching and the heat begins to enliven the rainy Pacific ... clothing, realizing that they didn’t work out as much during ... cause a sudden surge of people eager to look their ...
(Date:7/12/2014)... Wright & Schulte LLC, an experienced law firm who ... (case #59776/2014), announces they have launched a new TV ... popular hair dye, Just For Men, has caused some men ... other areas. In addition to detailing symptoms that are allegedly ... advertisements being run by Wright & Schulte LLC will also ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 ... score of 4.1 out of 5. This above-average ... have been underpinning buyer negotiation power over the ... analyst Anna Son, “during the period, surging demand ... costs associated with new product development, have placed ...
(Date:7/12/2014)... July 12, 2014 The largest pure ... is pleased to announce that it will be opening ... new facility will join four Atlanta-based Nova Medical Centers’ ... at 3209 Deans Bridge Road, and will be open ... , “With Nova’s treatment philosophy of rapid return-to-work ...
(Date:7/11/2014)... Recently, MagicQuinceaneraDresses.com, the popular online supplier of special ... Quinceanera dresses . The company’s new items are ... without paying a large amount of money. They are ... , The company’s online shop has become a one ... outfits. In addition to exquisite Quinceanera dresses, it also ...
Breaking Medicine News(10 mins):Health News:Best Summer Cosmetic Surgeries Revealed in Article By Seattle Plastic Surgeon 2Health News:Just for Men Lawsuit News: TV Campaign Launched by Wright & Schulte LLC to Inform Consumers of the Alleged Association between the Popular Hair Dye and Chemical Burns 2Health News:Just for Men Lawsuit News: TV Campaign Launched by Wright & Schulte LLC to Inform Consumers of the Alleged Association between the Popular Hair Dye and Chemical Burns 3Health News:Just for Men Lawsuit News: TV Campaign Launched by Wright & Schulte LLC to Inform Consumers of the Alleged Association between the Popular Hair Dye and Chemical Burns 4Health News:Floor-Grade Instruments Procurement Category Market Research Report from IBISWorld has Been Updated 2Health News:Floor-Grade Instruments Procurement Category Market Research Report from IBISWorld has Been Updated 3Health News:Floor-Grade Instruments Procurement Category Market Research Report from IBISWorld has Been Updated 4Health News:Nova Medical Centers To Open New Facility in Augusta, Georgia 2Health News:Cheap Quinceanera Dresses Now Available At MagicQuinceaneraDresses.com 2
... PolyScript(R) Labels Enable Fast and Cost-Effective CustomizationSOUTHFIELD, Mich., April ... manufactured specifically to provide equipment with safety warnings or ... to help engineering industries meet the exacting demands made ... (R) and PolyScript ...
... April 1 The following was released today ... Healthcare & Health IT Reporters, Editors, ... WHO: American Health Information Management Association ... Beyond Compliance to Strategic Advantage WHEN: ...
... Derma Sciences, Inc. ... care products, reported that sales for 2008 rose 47.1% year-over-year, ... higher sales of proprietary advanced wound care products led by ... $34.1 million in 2007. The Company,s loss increased consistent with ...
... The Quantum Group, Inc. (NYSE Amex: QGP ... transitioned to Continental Stock Transfer and Trust Company to act ... Quantum President & CEO, commented, "Continental Stock Transfer has been ... well regarded reputation as a comprehensive and customer-centric company that ...
... Alere,s groundbreaking Healthy Kids Program offers tools for ... costs estimated at $14 billion annually- Employers and ... First of its kind personalized solution that provides ... obesity and helps parents and kids become healthierMARIETTA, ...
... Could Save Millions on Expensive Social Services CHICAGO, ... for people who are homeless, have a mental illness, ... and cost of expensive public services such as state ... report released Thursday by the Heartland Alliance Mid-America Institute ...
Cached Medicine News:Health News:Schreiner ProTech Introduces Intelligent Marking Solutions Achieving Process and Cost Optimizations 2Health News:Derma Sciences Reports Fourth Quarter, Year-End Results for 2008 2Health News:Derma Sciences Reports Fourth Quarter, Year-End Results for 2008 3Health News:Derma Sciences Reports Fourth Quarter, Year-End Results for 2008 4Health News:Derma Sciences Reports Fourth Quarter, Year-End Results for 2008 5Health News:Derma Sciences Reports Fourth Quarter, Year-End Results for 2008 6Health News:Derma Sciences Reports Fourth Quarter, Year-End Results for 2008 7Health News:Derma Sciences Reports Fourth Quarter, Year-End Results for 2008 8Health News:The Quantum Group Announces Transition to Continental Stock Transfer 2Health News:The Quantum Group Announces Transition to Continental Stock Transfer 3Health News:New Online Program Helps Parents Tackle Childhood Obesity 2Health News:New Online Program Helps Parents Tackle Childhood Obesity 3Health News:Study Links Reduced Use of Mental Health Facilities, Nursing Homes and Other Public Services to "Smart Investments" in Supportive Housing 2Health News:Study Links Reduced Use of Mental Health Facilities, Nursing Homes and Other Public Services to "Smart Investments" in Supportive Housing 3Health News:Study Links Reduced Use of Mental Health Facilities, Nursing Homes and Other Public Services to "Smart Investments" in Supportive Housing 4Health News:Study Links Reduced Use of Mental Health Facilities, Nursing Homes and Other Public Services to "Smart Investments" in Supportive Housing 5
(Date:7/11/2014)... , July 11, 2014 Research ... "Global Hypodermic Needles Market 2014-2018" report to their ... A hypodermic needle is a hollow needle commonly ... body or or to extract fluids from it. A ... or to inject substances that cannot be ingested. Hypodermic ...
(Date:7/11/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/tjlw9k/immunoprotein ... "Immunoprotein Diagnostic Testing Market - Forecasts to 2019: ... 6% and is expected to be valued at ... http://photos.prnewswire.com/prnh/20130307/600769 ... been segmented according to immunoprotein types which include ...
(Date:7/10/2014)... , 11. Juli 2014 /PRNewswire/ ... Kameras für die molekulare Bildgebung, einschließlich ... heute die CE-Zulassung für sein Navigator ... kann Dilon das Produkt jetzt europaweit ... den Großteil der europäischen Länder ausgedehnt ...
Breaking Medicine Technology:Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 2Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 3Immunoprotein Diagnostic Testing Market - Forecasts to 2019: Expected to grow at the highest CAGR of 6% and is expected to be valued at USD 4,943.0 million 2Dilon erhält CE-Zulassung für sein Navigator-Gamma-Sondensystem 2
... study ... pediatric liver transplant patients, COLUMBIA, Md., Aug. 21 ... the peer-reviewed journal Liver Transplantation, have,further developed our understanding ... pediatric liver-transplant patients,post-transplantation., Working in a cooperative group ...
... 21 Novavax, Inc.,(Nasdaq: NVAX ) today announced ... discuss results from the Phase I/IIa human clinical,trial of ... Eastern Time on August 26, 2008., The call ... Dr. Rahul Singhvi and other members of senior management, ...
Cached Medicine Technology:New Data Support Earlier Suggested Guidance for Levels of Cell-Mediated Immunity in Pediatric Liver Transplant Patients 2New Data Support Earlier Suggested Guidance for Levels of Cell-Mediated Immunity in Pediatric Liver Transplant Patients 3Novavax to Present Phase I/IIa Trial Data Results in an Investor Conference Call on August 26, 2008 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: