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Shire Expands Gastrointestinal Patient Assistance Program for Uninsured or Unemployed Americans
Date:5/18/2009

th a syndrome that may be difficult to distinguish from an ulcerative colitis flare-up. If you experience cramping, diarrhea, fever, headache or rash, talk to your doctor immediately. Some patients taking mesalamine have reported heart-related hypersensitivity reactions, such as inflammation of the heart muscle and inflammation of the lining of the heart. Tell your doctor if you have problems with your liver or kidneys.

In worldwide clinical trials, Lialda was generally well tolerated. The most common adverse events were headache and flatulence. As with other medications, some serious side effects may occur. Less than 1% of patients experienced inflammation of the pancreas, which led to discontinuation of therapy with Lialda.

Lialda(R) is a registered trademark of Shire LLC.

MMX(R) is a registered trademark owned by Cosmo Technologies Ltd, Ireland, a wholly-owned subsidiary of Cosmo Pharmaceuticals SpA.

About PENTASA

Important Safety Information

PENTASA is approved for the induction of remission and for the treatment of mildly to moderately active ulcerative colitis.

PENTASA is generally well tolerated and most side effects are mild. In worldwide clinical studies, the most common side effects were diarrhea, headache, nausea, abdominal pain, upset stomach, vomiting, and rash. As with other medications, some serious side effects may occur. You should not take PENTASA if you are allergic to salicylates, such as aspirin. Tell your doctor if you have problems with your liver or kidneys. While taking PENTASA, visit your doctor periodically. If you have any questions about PENTASA, please talk to your doctor.

Pentasa(R) is a registered trademark of Ferring A/S Corp.

About SHIRE PLC

Shire's strategic goal is to become the leading specialty biopharmaceutical company that focuses on meeting the
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SOURCE Shire plc
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