Navigation Links
Shining the soothing light
Date:10/21/2013

Almost all patients suffering from head and neck squamous cell carcinoma (HNSCC) develop canker sores, a complication resulting from different modalities of treatment, namely stem cell transplantation, chemotherapy, and radiotherapy. Canker sore is divided in five grades (zero to four) by the World Health Organization (WHO), with severe cases (grades 3 and 4) being associated with pain, weight loss, poor quality of life, and higher hospital costs due to increased healthcare needs. Severe canker sore can also lead to treatment interruption, which may decrease the patient's chances of surviving the cancer.

No effective preventative strategy is currently available for canker sore, but prospective trials of low-level laser therapy (LLLT) done in HNSCC patients undergoing chemoradiotherapy showed promising results. However, additional trials detected a high incidence of canker sore among patients, leaving the question of whether LLLT can effectively prevent canker sore still open.

Now, a group of scientists led by Dr. Heliton Spindola Antunes at the National Cancer Institute (INCA) in Rio de Janeiro, Brazil, has successfully performed a definitive trial showing that LLLT reduces the occurrence of canker sore in HNSCC patients undergoing concurrent chemoradiotherapy and improves patient's quality of life.

The trial was performed with 94 HNSCC patients undergoing chemoradiotherapy. They were divided into two groups of 47 individuals, one of which received LLLT while the other received placebo. Researchers observed a significant difference in the incidence of canker sore grades 3 and 4 between groups. For instance, while in the group of patients receiving LLLT only three patients developed severe cases of canker sore, in the group receiving the placebo this number was 19. There were also significant differences in the absence of canker sore (grades 0-1), with the LLLT group having 59.6% of patients free of canker sore as opposed to 21.3% in the placebo group. The LLLT group had less severe oral pain and, as a result, used fewer opioid analgesics. They were also less likely to require gastrostomy (a surgical opening into the stomach for nutritional support) throughout the cancer treatment.

"For ethical reasons," says Dr Antunes, "all patients who developed canker sore grades 3 or 4 in the placebo arm were then offered the option of receiving LLLT. They all improved to grade 2 or lower, supporting the evidence that LLLT is an effective choice to prevent or treat canker sore in these patients."


'/>"/>

Contact: Heliton Spindola Antunes
hspindola@inca.gov.br
55-213-207-6597
Publicase Comunicao Cientfica
Source:Eurekalert

Related medicine news :

1. Mother-Baby Sleep Experts Offer Tips for Soothing Crying Babies, Giving Exhausted Mothers Alternatives to Crying It Out
2. Soothing sounds during cataract surgery reduces patient anxiety
3. Cataract Patients Relax to a Soothing Beat, Study Says
4. Nationwide Title Clearing, Inc. Prepares for “Light the Night Walk” for Cancer Fundraising
5. Into Action Treatment Sponsors NOPE Annual Candlelight Vigil
6. Specialized Lighting Products Designed by Daylight Now Offered by Rehabmart.com
7. Deepak Chopra Introduces Dream Weaver App for Smartphones with Strobe Lights, Making It Easy to Experience the Benefits of Meditation & Deep Relaxation Automatically
8. Mesothelioma Awareness Day Sheds Light on Deadly Cancer
9. Joseph Gordon-Levitt’s “Don Jon” Spotlights the Health Problems with Porn
10. Go Healthy Next Announces the SaunaFix, a Portable Sauna Featuring Near Infrared Light Therapy
11. FHFA Highlights Homeowners HARP Refinancing: Eligibility Is Easier
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... AZ (PRWEB) , ... February 10, 2016 , ... Ongoing ... the Aging Life Care Association™ (ALCA) to conduct a survey that takes a closer ... experts released today illustrates the prevalence and causes of TBI among the aging population, ...
(Date:2/10/2016)... (PRWEB) , ... February 10, 2016 , ... AxoGen, Inc. ... will report results for the fourth quarter and full year ended December 31, 2015 ... a conference call and webcast for the investment community following the release at 4:30 ...
(Date:2/10/2016)... ... ... For additional information contact Phyllis Strupp 480-488-5858 , Brain improves with age, ... Guide to Brain Training" by award-winning author Phyllis Strupp explains how brain ... 16, 2016. A free review copy is available to the media at NetGalley ...
(Date:2/10/2016)... ... February 10, 2016 , ... IDEX Health & Science, LLC ... steel (PLS) columns combine the strength of traditional stainless steel with the chemical ... samples while operating at ultra-high pressures of 20,000 psi. The higher operating pressures ...
(Date:2/10/2016)... , ... February 10, 2016 , ... The recreational use ... enthusiasts in the state still face a lot of restrictions as to where they ... intended for private, personal use” and that cannabis “may not be consumed openly or ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... --> --> ... Packaging Equipment Market by Package Type (Blister, Strip, Bottle, ... Type (Tablet, Powder, Cream, Syrup, Aseptic Liquid, Aerosol) - ... market during the forecast period of 2015 to 2020. ... of 6.9% during the forecast period to reach USD ...
(Date:2/10/2016)... 10, 2016 The campaign aims to ... 5 years reach the milestone of their 5 th birthday ... ensure 2,50,532 children between the ages of 2 - 5 years ... --> The campaign aims to ensure ... reach the milestone of their 5 th birthday   ...
(Date:2/9/2016)... , Feb. 9, 2016  Insulet Corporation (NASDAQ: PODD ... insulin pump technology with its OmniPod ® ... Lemoine has been appointed to Insulet,s Board of Directors. ... directors, eight of whom are independent. --> ... of audit and finance experience and a deep knowledge of ...
Breaking Medicine Technology: