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Shining a light on heart disease
Date:5/1/2014

ignal provides an indication of the amount of nanoparticles and therefore inflammatory markers - present.

Dr Pasquale Maffia, senior lecturer in immunology at the University of Glasgow, said "Using this nanoparticle technology, the primary aim of the research is to develop a highly-sensitive but relatively affordable means of measuring inflammatory molecules in samples of atherosclerotic plaque from patients which could enable the clinician to forecast how the disease will progress."

It is hoped in the future that the nanoparticles can be further customised to enable the delivery of anti-inflammatory drugs.

Dr Maffia added: "The energetic vibrations could be harnessed as a drug release mechanism which could be time-controlled by the flick of a switch. The major advantage of this set-up is that the equipment is portable, so this novel nanoparticle diagnosis and treatment system could potentially be made accessible to anyone."

The funding award is part of the EPSRC Healthcare Technologies theme which plays a vital role in sponsoring basic research capabilities to create new techniques and technologies to address national and global health challenges.

The team involved in the project are: Professor Duncan Graham and Dr Karen Faulds, University of Strathclyde; Dr Pasquale Maffia, Professor Naveed Sattar, Professor Iain McInnes and Professor Paul Garside, University of Glasgow; and Professor Mark Girolami of the University of Warwick a composite of physical scientists who are specialists in nanoparticle technology, information technologists capable of interpreting and presenting data from complicated nanoparticle assays and clinical partners who are interested in how best to utilise this new information in improved healthcare practice.


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Contact: Lachlan Mackinnon
corporatecomms@strath.ac.uk
University of Strathclyde
Source:Eurekalert  

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