Navigation Links
Shingles Raises Stroke Risk: Study

Patients with the virus should be monitored for high blood pressure, expert says

THURSDAY, Oct. 8 (HealthDay News) -- Adults with the skin disease shingles appear to be at raised risk for stroke, especially when it affects the area around the eyes, researchers report.

Previous reports have linked shingles with stroke risk, but "the exact frequency and risk for these phenomena are still unknown," said study lead author Dr. Jiunn-Horng Kang, a principal investigator in the Neuroscience Research Center of Taipei Medical University Hospital, Taiwan. His team published their findings in the November issue of Stroke.

"Our study is the first to explore these issues with a nationwide population-based data," Kang said.

Shingles is a painful skin rash resulting from infection by the varicella zoster virus, which causes chickenpox. The virus remains in the body after recovery from chickenpox and can erupt again to cause shingles.

Kang and his colleagues studied data on 7,760 adult Taiwanese who were treated for shingles between 1997 and 2001. In the year after treatment, 133 of them, or1.7 percent, had strokes. The incidence in a control group of 23,280 adults who were not treated for shingles was 1.3 percent (306 people).

Analysis of the data found that the risk of stroke in that one-year period was 31 percent higher in the shingles group. The incidence was dramatically higher for those with a shingles infection in or around the eye -- nearly 4.3 times higher than in the control group.

Strokes can be ischemic, caused by a blood clot blocking a brain artery, or hemorrhagic, due to rupture of a blood vessel. The study found a 31 percent higher incidence of ischemic strokes, the most common kind, and a 2.79-times higher incidence of hemorrhagic stroke in the shingles group.

"The major mechanism of our findings is that stroke results from herpes zoster virus-induced vasculopathy [blood vessel damage]," Kang said. "The vessel to the brain damaged by the virus could be occluded [blocked] or ruptured."

"However, several other factors could also be involved," he added.

No known treatment exists to reduce the apparent risk of stroke that results from shingles infection, Kang said. "Our interest and ongoing research are focused on whether early anti-viral treatment for herpes zoster can reduce the risk of stroke," he said. "Also, from the clinical view, patients who have a shingles attack should be aware of the risk of stroke, and intensive monitoring and management of pre-existing risk factors for stroke, such as hypertension, hyperlipidemia [raised lipid levels] and diabetes, should be emphasized."

Shingles usually starts as a rash on one side of the face or body, which often causes pain, itching and tingling. Attacks can last for two to four weeks. The incidence of shingles increases with age, and the U.S. Centers for Disease Control and Prevention recommends most people over 60 be vaccinated against the virus, with the major exception being those with weakened immune systems.

While there have been scattered reports about a possible association of shingles with stroke, "to my knowledge this is the first study to link shingles very specifically with stroke," said Dr. Daniel Lackland, professor of epidemiology and medicine at the Medical University of South Carolina, and a spokesman for the American Stroke Association.

"It might be a little too early for a lot of clinical implications here," Lackland said. "But a physician who is treating someone with shingles should emphasize the importance of traditional risk factors for stroke, and let the patient know that your risk might be a little bit increased and you should pay more attention to high blood pressure, cholesterol and the like."

More information

Learn the basics about shingles from the U.S. National Library of Medicine.

SOURCES: Jiunn-Horng Kang, M.D., principal investigator, Neuroscience Research Center, Taipei Medical University Hospital, Taiwan; Daniel Lackland, M.D., professor, epidemiology and medicine, Medical University of South Carolina, Charleston; November 2009 Stroke

Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Oxycodone May Reduce Shingles Pain
2. Rheumatoid Arthritis Drugs Raise Shingles Risk
3. Gypsum Wallboard from CertainTeeds Moundsville, W. Va., Plant and Roofing Shingles among Building Materials Donated to St. Jude Dream Home(R)
4. CDC Recommends Shingles Vaccine for Those Over 60
5. Mayo Clinic Proceedings Article Offers New Data About the Impact of the Shingles Virus on Healthy Adults
6. Mayo Clinic article offers data about shingles virus
7. The 24th Annual Great Sports Legends Dinner Raises More Than $6.3 Million for the Buoniconti Fund to Cure Paralysis
8. Study: Raises and Turnover Lower in Tennessee and Florida Than National Averages
9. Volcano Corporation Praises FAME Study Results
10. Fair Elections Now Coalition Praises Rep. Ben Lujan for Cosponsoring Fair Elections Now Act
11. Fair Elections Now Coalition Praises Rep. Peter DeFazio for Cosponsoring Fair Elections Now Act
Post Your Comments:
(Date:11/28/2015)... ... 2015 , ... Safe storage for contraceptive devices may not always be easy ... Jersey and the other from Bradley Beach, New Jersey, there is an easy solution ... having to replace NuvaRings more often than necessary. As such, it affords peace of ...
(Date:11/27/2015)... Los Angeles, CA (PRWEB) , ... November 27, 2015 , ... ... the conversation at the recent 2015 American Dental Association meeting in Washington D.C. revolved ... can help protect a patient’s overall health. The talk stressed the link between periodontal ...
(Date:11/27/2015)... ... 27, 2015 , ... An inventor, from Hopkinsville, Ky., thought ... at home, so he invented the patent-pending ELECTRONIC M.D. , The ELECTRONIC M.D. ... doing so, it could help to prevent potential overdose situations. As a result, ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... MPWH, the No.1 Herpes-only dating community in ... (see Table 1-1 ). More than 3.7 billion people under the age of ... 1 (HSV-1), according to WHO's first global estimates of HSV-1 infection . , "The ...
(Date:11/27/2015)... ... November 27, 2015 , ... Keeping in ... for mental health and wellness consultation, has collaborated with a leading web-based marketplace ... knowledge gap experienced by parents and bring advice from parenting experts within their ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... --> ... att använda SyMRI för att hitta optimal ... med multipel skleros (MS) eller hjärntumörmetastaser och ... för att kunna använda SyMRI Research Edition ... kan man generera flera konstrastbilder från en ...
(Date:11/26/2015)... -- Research and Markets ( ) has ... Horizons and Growth Strategies in the Italian Therapeutic ... Forecasts, Competitive Intelligence, Emerging Opportunities" report to ... --> This new 247-page report provides ... monitoring market, including emerging tests, technologies, instrumentation, sales ...
(Date:11/25/2015)... THOUSAND OAKS, Calif. , Nov. 25, 2015 /PRNewswire/ ... of a Biologics License Application (BLA) with ... Administration (FDA) for ABP 501, a biosimilar candidate to ... the first adalimumab biosimilar application submitted to the FDA ... biosimilar pathway. Sean E. Harper , M.D., ...
Breaking Medicine Technology: