Navigation Links
Shift work in teens linked to increased multiple sclerosis risk
Date:10/17/2011

Researchers from Sweden have uncovered an association between shift work and increased risk of multiple sclerosis (MS). Those who engage in off-hour employment before the age of 20 may be at risk for MS due to a disruption in their circadian rhythm and sleep pattern. Findings of this novel study appear today in Annals of Neurology, a journal published by Wiley-Blackwell on behalf of the American Neurological Association and Child Neurology Society.

Previous research has determined that shift workworking during the night or rotating working hoursincreases the risk of cardiovascular disease, thyroid disorders, and cancer. Circadian disruption and sleep restriction are associated with working night shifts; these factors are believed to disturb melatonin secretion and increase inflammatory responses, promoting disease states. MS is a central nervous system autoimmune inflammatory disorder that has an important environmental component, thus investigating lifestyle risk factors, such as sleep loss related to shift work, is an important objective and the focus of the current study.

Dr. Anna Karin Hedstrm and colleagues from the Karolinska Institutet in Stockholm analyzed data from two population-based studiesone with 1343 incident cases of MS and 2900 controls and another with 5129 prevalent MS cases and 4509 controls. The team compared the occurrence of MS among study subjects exposed to shift work at various ages against those who had never been exposed. All study subjects resided in Sweden and were between the ages of 16 and 70. Shift work was defined as permanent or alternating working hours between 9 p.m. and 7 a.m.

"Our analysis revealed a significant association between working shift at a young age and occurrence of MS," explains Dr. Hedstrm. "Given the association was observed in two independent studies strongly supports a true relationship between shift work and disease risk." Results showed that those in the incident MS cohort who had worked off-hour shifts for three years or longer before age 20 had a 2 fold-risk of developing MS compared with those who never worked shifts. Similarly, subjects in the prevalent cohort who engaged in shift work as teens had slightly more than a 2-fold risk of MS than subjects who never worked shifts.

The authors suggest that disruption of circadian rhythm and sleep loss may play a role in the development of MS; however the exact mechanisms behind this increased risk remain unclear and further study is needed.


'/>"/>
Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. Shift Work May Put Teens at Risk for Multiple Sclerosis
2. Shift Workers Show Rise in Stress Hormone
3. Stress hormones may increase cardiovascular risks for shift workers
4. Modern Shift Work Patterns May Be Less Harmful to Health
5. Modern shift work pattern potentially less harmful to health
6. Study finds shifting domestic roles for men who lost jobs in current recession
7. With Age, Focus on Body Shifts From Appearance to Function
8. Metabolic shift may offer early cancer clue
9. Working Night Shifts May Raise Diabetes Risk for Women
10. Scripps Research scientists show how shifts in temperature prime immune response
11. Despite Radiation in Japan, Little Shift in Americans Views on Nuke Power: Poll
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star ... , Millions of individuals in the United States and Canada wear eyeglasses. Once considered ... both correct vision and make a fashion statement. Even celebrities use glasses as a ...
(Date:6/26/2016)... ... ... Brent Kasmer, a legally blind and certified personal trainer is helping to develop a weight ... app plans to fix the two major problems leading the fitness industry today:, ... program , They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... , ... June 25, 2016 , ... "With 30 hand-drawn ... specific project," said Christina Austin - CEO of Pixel Film Studios. , ProHand ... all within Final Cut Pro X . Simply select a ProHand generator and ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the ... In terms of the latter, setting the bar too high can result in disappointment, ... just slow progress toward their goal. , Research from PsychTests.com reveals ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... Conference and Scientific Sessions in Dallas that it will receive two significant new ... the grants came as PHA marked its 25th anniversary by recognizing patients, medical ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  Collagen Matrix, Inc., ... development and manufacturing of collagen and mineral based ... today that Bill Messer has joined ... to further leverage the growing portfolio of oral ... Bill joins the Collagen Matrix executive ...
(Date:6/24/2016)... 2016   Bay Area Lyme Foundation , ... Center for Tick Borne Illness , Harvard Medical ... Hacking Medicine, University of California, Berkeley, and the ... five finalists of Lyme Innovation , the ... 100 scientists, clinicians, researchers, entrepreneurs, and investors from ...
(Date:6/24/2016)... June 24, 2016 Research ... "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural Health ... Structural electronics involves electronic and/or electrical ... structures, replacing dumb structures such as vehicle bodies ...
Breaking Medicine Technology: