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Sharp Rise in Risk With New Breast Cancer Gene, Scientists Say
Date:8/7/2014

docrine neoplasia, but up to now the gene has not been associated with breast cancer.

Researchers found that women with the disease had more than double the risk of also developing breast cancer.

"If you have multiple endocrine neoplasia, then perhaps more intense breast surveillance may be warranted," Foulkes said. "But because it's so rare, you wouldn't say to a woman with a family history of breast cancer, it's probably due to MEN1. It's important for people who have multiple endocrine neoplasia, but probably not for everyone with a family history of breast cancer."

More information

For more about the BRCA gene, visit the U.S. National Cancer Institute.

SOURCES: Marc Tischkowitz, Ph.D., researcher, department of medical genetics, University of Cambridge, U.K.; Roger Greenberg, M.D., Ph.D., associate professor, cancer biology, Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia; William Foulkes, Ph.D., director, Program in Cancer Genetics, Center for Translational Research in Cancer, McGill University, Montreal; Aug. 7, 2014, New England Journal of Medicine


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