Navigation Links
Shark cartilage shows no benefit as a therapeutic agent for lung cancer
Date:5/26/2010

HOUSTON - In the first scientific study of its kind, shark cartilage extract, AE-941 or Neovastat, has shown no benefit as a therapeutic agent when combined with chemotherapy and radiation for patients with advanced non-small cell lung cancer, according to researchers at The University of Texas MD Anderson Cancer Center.

The study was published in the Journal of the National Cancer Institute; the findings were first presented at the 43rd annual meeting of the American Society of Clinical Oncology.

The absence of blood vessels in cartilage as well as preclinical studies analyzing cartilage extracts have supported the hypothesis that cartilage contains inhibitors of angiogenesis. Also, shark cartilage has long intrigued the public due to the belief that the incidence of cancer in this cartilaginous fish is very rare. Early Phase I and II studies in lung and renal cancers suggested some benefit to patients when AE-941 was given at higher doses, said Charles Lu, M.D. associate professor in MD Anderson's Department of Thoracic Head and Neck Medical Oncology.

"This is the first large Phase III randomized trial of shark cartilage as a cancer agent. A unique and important aspect about this shark cartilage study was that this product, Neovastat, was never sold over-the-counter, unlike other shark cartilage compounds previously studied. The company, Aeterna Zentaris, developed the compound as a pharmaceutical as opposed to a compound sold for profit that is available over the Internet, for example," said Lu, the study's national principal investigator and corresponding author.

The international Phase III study enrolled 379 newly-diagnosed untreated Stage III non-small cell lung cancer patients at 53 sites in the United Sates and in Canada from June 2000 to February 2006. MD Anderson enrolled 60 patients in the trial.

The study was initiated at the request of, and was supported by, the National Cancer Institute (NCI) wh
'/>"/>

Contact: Scott Merville
smerville@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Shark Cartilage Not Beneficial in Advanced Lung Cancer
2. Shark Attack Study Announced: Politics of Bite Incidents Under Review
3. NIH study confirms location of stem cells near cartilage-rich regions in bones
4. Nanofiber Gel May Spur Growth of New Knee Cartilage
5. Cartilage repair can improve life, ease burden on health services
6. Gene Therapy Shows Promise for Muscular Dystrophy
7. CA-125 change over time shows promise as screening tool for early detection of ovarian cancer
8. Fat in Males, Females Differs Genetically, Mouse Study Shows
9. Social Media Driving Leads & Sales, New Report Shows
10. Drug in new class of targeted therapies shows early promise against blood-related cancers
11. Varicose vein study shows radiofrequency ablation causes less post-operative pain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... 10, 2014 Register to download the ... streamed the live webinar ‘Capitalizing on the Shifting Sands ... group of several M&A experts in the energy sector ... energy transaction marketplace. These experts shared their insights into ... market in this sector has been revitalized. This roundtable ...
(Date:7/10/2014)... MI (PRWEB) July 10, 2014 ... treatment program that gets clients off to a great ... they can believe in, has launched a new Eating ... , The new section highlights:, , ... and Statistic Manual of Mental Disorders (DSM-IV), including anorexia ...
(Date:7/10/2014)... THURSDAY, July 10, 2014 (HealthDay News) -- Nature, not ... intelligence of individual chimpanzees, a new study finds. ... it comes to cognitive [thinking] abilities in chimpanzees," William ... Atlanta, said in a news release from the journal ... give insight into the evolution of intelligence in humans, ...
(Date:7/10/2014)... News) -- Men who have a vasectomy may be ... study suggests. But the risk is comparatively small, ... the study said more research is needed to determine ... the study, Harvard researchers analyzed data from more than ... starting in 1986. During that time, 6,023 cases of ...
(Date:7/10/2014)... experts on aggression, who research issues ranging from child ... World Meeting of the International Society for Research on ... , Georgia State University is hosting the prestigious world ... continents. , "We are excited to be bringing together ... will help produce fresh ideas about the causes, consequences ...
Breaking Medicine News(10 mins):Health News:Register to Download Merrill DataSite's Report: Capitalizing on the Shifting Sands of the Energy Market 2Health News:Latest A Forever Recovery Launches Eating Disorders Section on Website 2Health News:Like Humans, Chimps' Smarts May Rely on Genes 2Health News:Study Links Vasectomy to Aggressive Prostate Cancer 2Health News:Study Links Vasectomy to Aggressive Prostate Cancer 3Health News:Georgia State hosts national conference on aggression 2Health News:Georgia State hosts national conference on aggression 3
... Study reports high success rate for new test, with results ... A new test can rapidly identify active tuberculosis in people ... about half of all people with active TB, the disease-causing ... new diagnostic tests are needed to help control the spread ...
... Irvine researchers have created a new approach that ... specific cells and organs. Kenneth Longmuir, associate ... professor of anatomy & neurobiology, used liposomes, small ... lipid molecules, as "packages" for the cancer chemotherapeutic ...
... N.Y., SEPT. 25, 2009 Journalists are invited to attend ... health care experts who will review and develop programs that ... The symposium, which will be held Oct. 8 and ... March of Dimes, the American College of Obstetricians and Gynecologists, ...
... testing effects on women and their offspring, , FRIDAY, ... women can cause serious consequences in both mothers and ... treatments. , An update on clinical trials was to ... American Thyroid Association, in Palm Beach, Fla. , "Detection ...
... ... costs, saving time and money , ... Philadelphia, PA (PRWEB) September 25, 2009 -- Observations from Excel ... Philadelphia region, indicate that awareness levels for Direct Access, a law that allows people ...
... causes gastric cancer, it is still controversial that whether ... prevention of gastric cancer. This is especially important for Yamagata ... of gastric cancer in the world. A research ... World Journal of Gastroenterology addresses this question. A ...
Cached Medicine News:Health News:Faster Detection of TB May Be on the Horizon 2Health News:UCI researchers create new strategy for highly selective chemotherapy delivery 2Health News:Experts to review quality improvement programs to prevent preterm birth 2Health News:Experts to review quality improvement programs to prevent preterm birth 3Health News:Studies Evaluate Thyroid Treatment During Pregnancy 2Health News:According to Excel Physical Therapy and Fitness, Awareness Still Low for Law that Allows People to go Directly to a Physical Therapist without a Doctor's Prescription 2Health News:According to Excel Physical Therapy and Fitness, Awareness Still Low for Law that Allows People to go Directly to a Physical Therapist without a Doctor's Prescription 3Health News:Does Helicobacter pylori eradication therapy prevent gastric cancer? 2
(Date:1/15/2014)... Jan. 15, 2014 The Cadence Fitness & Health ... by the Medical Fitness Association, a non-profit organization assisting ... full potential. The Cadence Fitness & Health Center is ... and second in the Chicagoland area. "The ...
(Date:1/15/2014)... , Jan. 15, 2014 Reportlinker.com ... is available in its catalogue: ... Drug Forecast and Market Analysis to 2022 ... PharmaPoint: Atopic Dermatitis - India Drug Forecast ...
(Date:1/15/2014)... Jan. 15, 2014 Reportlinker.com announces ... is available in its catalogue: ... Technologies for Advanced Drug Delivery Systems ... http://www.reportlinker.com/p01941928/Global-Markets-and-Technologies-for-Advanced-Drug-Delivery-Systems----Focus-on-Routes-of-Administration.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_Delivery_Technology ...
Breaking Medicine Technology:Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 2PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 3PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 4PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 16
... Point-of-Care Partners—a national health information technology (HIT) strategy ... for its role in helping Michigan attain the ...  The commendation came as part of Surescripts, fifth ... factors including each state,s overall ePrescribing volume. ...
... , a privately-held aesthetic medical device company, today announced the ... Artefill ® for the treatment of atrophic acne scars conducted ... Medical. The article, which appears in the September 2010 issue ... a significant and lasting effect on patient atrophic acne scars ...
Cached Medicine Technology:Point-of-Care Partners Recognized for Role in Managing SEMI 2New Study Published in Journal of Drugs in Dermatology Finds Artefill Effective in Treating Atrophic Acne Scars 2
For temporary cardiac pacing after open heart surgery. The zig-zag portion of the heartwire is embedded into the desired area of the myocardium (epicardially)....
... (RAM) is the first visual examination device that ... in eyes with glaucoma, cataract, and macular disease. ... test each eye easily in under 60 seconds. ... Columbia University in New York City, the RAM ...
... The STRATUSOCT is a diagnostic imaging device ... the retina for objective measurement and subjective ... and retinal diseases. The STRATUSOCT images and ... layer and the optic disc using the ...
The Hybrid Fixator consists of Three basic components: rings, wires, clamps. Final fracture reduction can be easily performed after frame assembly....
Medicine Products: