Navigation Links
Sexual Side Effects From Propecia, Avodart May Be Irreversible

By Steven Reinberg
HealthDay Reporter

THURSDAY, March 10 (HealthDay News) -- Drugs frequently prescribed to treat hair loss or an enlarged prostate may contribute to irreversible sexual dysfunction in men, new research finds.

Use of dutasteride (Avodart) and finasteride (Proscar and Propecia) were linked to erectile dysfunction, depression and loss of libido in a review of existing studies.

In a small percentage of cases, symptoms persisted even after the medication was stopped.

For those men, "it's a life sentence," said lead researcher Abdulmaged M. Traish, a professor of biochemistry and urology at Boston University School of Medicine.

"No sex. No desire. Potential depression," Traish added.

Almost everyone who takes these drugs experiences some of these side effects, Traish said. "But, some experience it more drastically than others," he added.

The drugs -- prescribed to treat a common urological condition called benign prostatic hyperplasia (BPH) and baldness -- work by blocking androgen. In the case of BPH, this helps reduce the enlarged prostate, making urination easier.

But there's a downside. "We need androgen for erectile function, libido and ejaculation, and for just feeling good," Traish said.

Noting that increasing numbers of patients report ongoing sexual problems after they stop taking the drugs, Traish said, "That's where the light should be shined."

"I am not worried about those who stop taking the drug and get their life back, [my concern is] about those who stop taking the drug, but they don't get their life back," Traish said.

The consequences are important in terms of their quality of life, he said.

For the study, published in the March issue of the Journal of Sexual Medicine, Traish's team searched the available medical literature for reports of sexual side effects associated with finasteride and dutasteride.

About 8 percent of men taking the drugs reported erectile dysfunction, and 4.2 percent reported reduced libido, they found, compared with 4 percent and 1.8 percent of men receiving placebo, respectively.

Reduced ejaculation and semen volume and depression were also reported by some men, the researchers note.

Traish said doctors need to inform their patients about the potential side effects.

"As a physician you have a responsibility to take the time and explain to your patient that maybe not everyone will have these side effects, but you may, and in some cases they are irreversible," he said.

He also said alternative medications are available to treat BPH, including alpha-blockers such as Flomax, which work differently in the body. Often these are given in combination with Propecia or Avodart.

Commenting on the study, Dr. Bruce R. Kava, an associate professor of urology at the University of Miami Miller School of Medicine, agreed that "these drugs do cause some of these problems."

That the effects might not be reversible is a concern, he said. "But they haven't convinced me yet, based on this data, because they don't have any long-term data," Kava said.

Most urologists discuss potential side effects with their patients, Kava said. "We don't usually discuss long-term consequences that are irreversible, because most of us have not been aware of any long-term problems from these drugs," he said.

More information

For more information on erectile dysfunction, visit the U.S. National Library of Medicine.

SOURCES: Abdulmaged M. Traish, Ph.D., professor, biochemistry and urology, Boston University School of Medicine; Bruce R. Kava, M.D., associate professor, urology, University of Miami Miller School of Medicine, March 2011 Journal of Sexual Medicine

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Brain cell regrowth linked to benefits of exercise, sexual behaviors and reproductive issues
2. Popular drugs for common male health problems can affect their sexual health
3. Exploring religion, youth and sexuality
4. Queens University researcher connects cannabis use and sexual dysfunction
5. Sexual Issues Often Unaddressed in Women Who Survive Cancer
6. Few women seek help for sexual issues after cancer treatment, but many want it
7. Supporters and opponents of a special blessing for homosexuals share many values
8. New survey device gets better information on teenage sexual behavior
9. Many Men Over 75 Still Sexually Active: Study
10. Lesbian, gay and bisexual teens singled out for punishment
11. Increased age of sexual consent in Canada may not protect teens at greatest risk: UBC study
Post Your Comments:
Related Image:
Sexual Side Effects From Propecia, Avodart May Be Irreversible 
(Date:11/25/2015)... ... ... Today, Mothers Against Drunk Driving (MADD) learned that the number of ... time since 2011. In 2014, there were 9,967 fatalities involving an alcohol impaired driver, ... Traffic Safety Administration (NHTSA), 32,675 people were killed in traffic crashes in 2014. Drunk ...
(Date:11/25/2015)... ... November 25, 2015 , ... In honor ... Periwinkle Pioneers, individuals and groups responsible for advancing care for pulmonary hypertension (PH) ... nominated by the public, will receive special recognition throughout 2016 as part of ...
(Date:11/25/2015)... ... 25, 2015 , ... Privately owned Contract Development and Manufacturing ... its current state of the art research, development and manufacturing facility outside of ... manufacturing capacity as well as to support its clients’ growing research and development ...
(Date:11/25/2015)... ... November 25, 2015 , ... Many people know of ... weight gain, cold hands, and dry skin. But many people who find their cholesterol ... exercise regimen instead of their thyroid, especially if they don’t have any of the ...
(Date:11/25/2015)... ... November 25, 2015 , ... Since its launch in ... involving adult stem cell therapies to patients with chronic degenerative medical conditions. Now, ... a Registered Trademark (RTM). , Organizations are required to hold a registered trademark ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... 2015  Today AVACEN Medical announced the issue of United States patent ... Adjustment ". This patent shields the company,s AVACEN 100 dry heat therapy medical device and specific ... Photo - ... ... ...
(Date:11/25/2015)... YORK , November 25, 2015 ... market of self-monitoring blood glucose devices was valued at ... grow with a CAGR of 5.7% during 2015 - ... geriatric population and increasing prevalence of diabetes. In addition, ... diabetes care is also contributing to the growth of ...
(Date:11/25/2015)... Pennsylvania , November 25, 2015 - ... Continuing Medical Education (CME) --> ... Continuing Medical Education (CME) --> ... Care Continuing Medical Education (CME) ... medical information products and services, will feature latest diagnostic imaging textbooks ...
Breaking Medicine Technology: