Navigation Links
Severity of hepatitis C and HIV co-infection in mothers contribute to HCV transmission to child
Date:4/27/2011

New research shows that high maternal viral load and co-infection with human immunodeficiency virus (HIV) are the only risk factors associated with vertical transmission of the hepatitis C virus (HCV-VT). A variation in the infant's IL28B gene (CC) is associated independently with the spontaneous clearance of HCV genotype-1 among infected children. The status of IL28B in the mother or children did not increase risk of HCV-VT in this study. Findings are published in the May issue of Hepatology, a peer-reviewed journal of the American Association for the Study of Liver Diseases.

Chronic HCV affects 170 million individuals worldwide, with 10% to 15% of cases leading to cirrhosis and liver cancer. A major route of infection in children is vertical transmission of HCV (HCV-VT)known also as mother-to-child transmissionand may occur in utero or following birth (breast feeding). While medical evidence has described risk factors involved in HCV-VT, underlying transmission mechanisms and timing of disease transmission is not fully understood. Prior studies have investigated the relationship between HCV-VT and maternal HCV genotype, birth mode (vaginal or caesarean) and type of feeding (breast feeding or replacement), but results have been conflicting.

"Our study analyzed the role of IL28B in HCV-VT and the spontaneous clearance of HCV among infected infants," said ngeles Ruiz Extremera, M.D., of San Cecilio University Hospital in Spain. The team recruited 145 mothers who were infected with HCV and gave birth between 1991 and 2009. All women were Caucasian112 were HCV RNA positive and HIV negative; 33 were HCV RNA negative and HCV antibody positive. A total of 142 children were birthed by HCV-RNA positive mothers and 43 children to HCV-RNA negative mothers, all of whom were followed for six years or more. HCV-VT was defined as children who presented with HCV-RNA positive results from two blood samples.

Analysis showed that 61% of the 3
'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Gene linked to severity of autisms social dysfunction
2. Blood Marker Suggests Severity of Alzheimers Disease
3. Genes May Affect Severity of Drug Addiction
4. How sunlight may reduce the severity of multiple sclerosis
5. Hand Movements May Give Clues to ADHD Severity
6. Plasma protein appears to be associated with development and severity of Alzheimers disease
7. Studies confirm presence, severity of pollution in national parks
8. New possibility to determine the severity of appendicitis
9. M. D. Anderson develops tool to measure severity of chronic graft-vs.-host disease symptoms
10. Increased mortality rates seen in chronic hepatitis C patients with pre-cirrhotic advanced fibrosis
11. New Drug May Boost Hepatitis C Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/20/2014)... 20, 2014 RBSEO Services, which has ... companies, has announced it provides an affordable website SEO ... , This announcement would benefit those new and old ... but cannot afford to pay a big amount for ... of their websites in top search results for their ...
(Date:9/20/2014)... Columbus, OH (PRWEB) September 20, 2014 ... hip lawsuit is now in its third week in ... & Schulte LLC reports. Court documents indicate that the ... trial with testimony from a DePuy Orthopaedics vice ... metal-on-metal version of the company’s Pinnacle hip replacement. According ...
(Date:9/20/2014)... The children of Branches now have ... play they need. An empty lot at the Trish ... was transformed into a kid-designed playspace in less than ... Branches (@BranchesFL), ESPN (@TeamESPN), Disney (@CitizenDisney), area residents and ... playground is more than a playground. It’s a brain-expander, ...
(Date:9/19/2014)... (PRWEB) September 19, 2014 “Copay coupons,” ... sales of brand drugs among patients with prescription drug ... according to a new report from the Department ... General (OIG). Federal anti-kickback laws prohibit suppliers from offering ... by the federal government. , The report highlights that ...
(Date:9/19/2014)... Dallas, TX (PRWEB) September 19, 2014 ... equipment and solutions, today detailed the key role ... by two-way radios in the healthcare industry. ... operations and patient care – and in emergency ... the difference between life and death,” said Hugh ...
Breaking Medicine News(10 mins):Health News:RBSEO Services Announces Affordable Website SEO Service at Only $175 2Health News:Third Week of DePuy Pinnacle Hip Lawsuit Trial Focuses on Clinical Testing of Metal-on-Metal Hip Implant, Wright & Schulte LLC Reports 2Health News:Third Week of DePuy Pinnacle Hip Lawsuit Trial Focuses on Clinical Testing of Metal-on-Metal Hip Implant, Wright & Schulte LLC Reports 3Health News:Third Week of DePuy Pinnacle Hip Lawsuit Trial Focuses on Clinical Testing of Metal-on-Metal Hip Implant, Wright & Schulte LLC Reports 4Health News:Volunteers Improve Miami Kids’ Lives and Futures with Play 2Health News:Volunteers Improve Miami Kids’ Lives and Futures with Play 3Health News:Volunteers Improve Miami Kids’ Lives and Futures with Play 4Health News:PCMA: New OIG Report Cites Drug Manufacturer“Copay Coupon” Use in Medicare Part D 2Health News:BearCom Releases Guidelines on Using Two-Way Radios to Improve Communications and Enhance Patient Service in Healthcare 2Health News:BearCom Releases Guidelines on Using Two-Way Radios to Improve Communications and Enhance Patient Service in Healthcare 3Health News:BearCom Releases Guidelines on Using Two-Way Radios to Improve Communications and Enhance Patient Service in Healthcare 4
... of Meijer ... customers, ... Legacy of Leadership award in recognition of its free,antibiotic and free ... Service Awards luncheon of Michigan,Primary Care Association (MPCA), the nonprofit membership ...
... CHAPEL HILL A new study seeking to improve scientists, ... is higher in African-American women, is getting underway in 44 ... late Jeanne Hopkins Lucas, a North Carolina state senator who ... the Lineberger Comprehensive Cancer Center at the University of North ...
... time, increase physician productivity,and safety, WASHINGTON, ... wait time, and improve quality of care, ... voluntary consensus standards for,hospital-based emergency department care. ... coordination in emergency departments where high demand,and ...
... Corporation Award Based on Consistent, Long-term Revenue Growth, ... HSKA ) ("Heska") today announced it has ... by Deloitte LLP. The Technology Fast,50 lists the ... companies in Colorado based on percentage revenue growth ...
... type 1 a rare disease in which tumors grow ... by crosstalk between cells in the nerves and cells in ... National Institutes of Health (NIH) and the Department of Defense ... treating certain kinds of blood cancer curbs tumor growth in ...
... - Response Biomedical,Corporation (TSX: RBM, OTCBB: RPBIF) announces ... Rapid Detection Flu A+B Test at the 48th ... launching,the RAMP(R) Influenza A/B Assay in the United ... 3M(TM) Rapid Detection Flu A+B Test. This rapid ...
Cached Medicine News:Health News:Meijer Honored by Michigan Primary Care Association for Leadership in Promoting Health of Michigan Residents 2Health News:Meijer Honored by Michigan Primary Care Association for Leadership in Promoting Health of Michigan Residents 3Health News:UNC Lineberger launches 44-county study of breast cancer in black women 2Health News:UNC Lineberger launches 44-county study of breast cancer in black women 3Health News:NQF Endorses Measures to Address Care Coordination and Efficiency in Hospital Emergency Departments 2Health News:NQF Endorses Measures to Address Care Coordination and Efficiency in Hospital Emergency Departments 3Health News:Deloitte Names Heska Corporation to Colorado Technology Fast 50 2Health News:Deloitte Names Heska Corporation to Colorado Technology Fast 50 3Health News:Researchers identify mechanism, possible drug treatment for tumors in neurofibromatosis 2Health News:Researchers identify mechanism, possible drug treatment for tumors in neurofibromatosis 3Health News:Response Biomedical Announces Launch of RAMP(R) Technology in 3M(TM) Rapid Detection Flu A+B Test at ICAAC/IDSA Conference 2Health News:Response Biomedical Announces Launch of RAMP(R) Technology in 3M(TM) Rapid Detection Flu A+B Test at ICAAC/IDSA Conference 3Health News:Response Biomedical Announces Launch of RAMP(R) Technology in 3M(TM) Rapid Detection Flu A+B Test at ICAAC/IDSA Conference 4
(Date:9/19/2014)... The American Association for Homecare (AAHomecare) is ... has joined the AAHomecare Corporate Partner Program. ... have been actively involved in AAHomecare for much of ... grown into a major global manufacturer of home medical ... to increase efforts on behalf of the HME sector ...
(Date:9/19/2014)... 2014 Larry J. Merlo , President and ... speak before the National Press Club in Washington, ... move to stop selling tobacco products and its leadership in ... "Dramatic changes in our health care system pose ... Merlo has said. "CVS Health has a truly unique combination ...
(Date:9/19/2014)...  Lpath, Inc. (NASDAQ: LPTN ), ... today that it has entered into definitive agreements ... and 3,605,042 unregistered warrants in a registered direct ... share of common stock and one unregistered warrant ... will be $3.475.  The warrants have an exercise ...
Breaking Medicine Technology:Drive Medical Design & Manufacturing Joins AAHomecare Corporate Partner Program 2CVS Health CEO to Address National Press Club on Landmark Decision to Quit Tobacco, Leadership in Health Care Innovation 2CVS Health CEO to Address National Press Club on Landmark Decision to Quit Tobacco, Leadership in Health Care Innovation 3Lpath, Inc. Announces $12.5 Million Registered Direct Offering 2Lpath, Inc. Announces $12.5 Million Registered Direct Offering 3
... , BEDFORD, Ohio , Jan. 14 ... is pleased to announce FDA approval for the addition of ... line. This product is AP rated and is equivalent to ... for oropharyngeal and esophageal candidiasis, cryptococcal meningitis, and is indicated ...
... , , BETHLEHEM, Pa. , Jan. 13 ... and easy-to-use WHIN ® Safe Huber Needle , an implantable ... a single Huber Needle and provides clinicians with advanced protection ... http://www.newscom.com/cgi-bin/prnh/20081022/NYW008LOGO ) , There are three models of the WHIN ® ...
Cached Medicine Technology:Bedford Laboratories(TM) To Begin Shipping Fluconazole Injection 2Bedford Laboratories(TM) To Begin Shipping Fluconazole Injection 3Bedford Laboratories(TM) To Begin Shipping Fluconazole Injection 4B. Braun Introduces WHIN(R) Safe Huber Needle 2B. Braun Introduces WHIN(R) Safe Huber Needle 3B. Braun Introduces WHIN(R) Safe Huber Needle 4
Hydrophobic Acrylic Intraocular Lens, AC depth: 5.3....
... Alcon introduces an intraocular lens that ... to the natural human lens, the ... UV and high-energy blue light. But ... won't spoil your patient's view. That's ...
Single-Piece PMMA IOLs for the replacement of the human crystalline lens in the visual correction of aphakia....
Single Piece PMMA Lens (Refractive and Bifocal). Anterior chamber Lens....
Medicine Products: