Navigation Links
Severe heart attack damage limited by hydrogen sulfide
Date:9/19/2007

BIRMINGHAM, Ala. Administering hydrogen sulfide (H2S) directly into the heart during a simulated heart attack significantly reduces the tissue and cell damage often seen in oxygen-starved organs, according to a new study from researchers at the University of Alabama at Birmingham.

H2S boosts post-heart-attack function by helping to minimize reperfusion injury, an unwanted side effect of restoring blood flow swiftly to hearts suffering from low oxygen, the study authors said.

In testing on mice, the H2S injection led to a 72 percent reduction in the amount of severe heart-tissue death after restoring normal oxygen and blood flow to mice hearts. The 72 percent reduction compares to a much larger average amount of tissue death in un-treated mice hearts after the same 30 minutes of oxygen deprivation.

Findings on the protective qualities of H2S have broad implications for improving human survival after cardiac arrest, heart transplant and trauma in general, said David Kraus, Ph.D., a UAB associate professor in the Departments of Environmental Health Sciences and Biology and co-author on the new study.

One of the most damaging biological stresses on the heart and other organs from trauma or transplantation is the rapid change in oxygen levels, Kraus said. First theres a drop, which elicits a dramatic cellular adjustment to survive low oxygen, and then a rapid rise caused by resuscitation.

H2S as an internal bodily signal appears to serve as an important protective mechanism during the stress of low oxygen availability, he said.

The study was published Sept. 18 in the online Early Edition of the journal Proceedings of the National Academy of Sciences. The UAB researchers worked with a team led by David Lefer, Ph.D. from the Albert Einstein College of Medicine in Bronx, N.Y.

The tests were done by injecting H2S directly into the hearts of m
'/>"/>

Contact: Troy Goodman
tdgoodman@uab.edu
205-934-8938
University of Alabama at Birmingham
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Low Cholesterol Linked to Severe Depression and Violent Behavior in Men
2. Patients With Severe Hemophilia At Risk Of Developing Osteoporosis
3. Severe stress weakens immunity
4. Severe Acute respiratory Syndrome (SARS)
5. WHO Travel Advice to prevent spread of "Severe Acute Respiratory Syndrome (SARS)
6. Traffic pollution linked to severe asthma attacks
7. Severe sleep apnea can cause liver problems
8. Scientists Unveil Mechanism Behind Resistance to Severe Malaria
9. Strong Magnetic Stimulation Can Help Treating Severe Depression
10. Patients Suffering From Severe Mental Diseases Are At Risk Of Being Crime Victims
11. Acute Toxicity Of Nano-Scale Zinc Powder: Severe Renal Damage And Anemia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2015)... Los Angeles, CA (PRWEB) , ... August 27, 2015 , ... ... the most recent World Conference on Abdominal Wall Hernia Surgery involved many conversations between ... approved mesh options out there, the article notes that many different experts have different ...
(Date:8/27/2015)... ... August 27, 2015 , ... ... exploding legal marijuana industry with the launch of its Doobster platform, a HIPAA-compliant ... to order products from their smart phones and tablets. Well, Doobster, “The ...
(Date:8/27/2015)... ... August 27, 2015 , ... Infocast is pleased to announce ... in San Jose, CA. The first event dedicated to finding alternative solutions ... exists where battery development and energy storage innovation are concerned. Product developers, ...
(Date:8/27/2015)... ... 2015 , ... In addition to its existing Doctor of Philosophy in Leadership ... at its main campus in Reading: Doctor of Nursing Practice. , Alvernia’s Doctor ... practice nurses for the highest level of clinical nursing practice. , “Our vision ...
(Date:8/27/2015)... ... August 27, 2015 , ... Florida Hospital North Pinellas, located at 1395 South Pinellas Avenue in ... 2016. The new facility will be located at US Highway 19 North and Highlands Boulevard, ... August 18, and work on the project is slated to begin in September 2015. ...
Breaking Medicine News(10 mins):Health News:Recent Article on Hernia Mesh Developments Highlights Viable Options, But Shows a Need for Further Research, notes Dr. Shirin Towfigh 2Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 2Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 3Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 4Health News:Doobster Launches a Nationwide, Comprehensive On-Demand Medical Marijuana App 5Health News:Infocast Hosting First Conference Dedicated to Powering Wearable Devices & the IoT 2Health News:Alvernia University Now Offering Three Doctoral Degree Programs 2Health News:Florida Hospital North Pinellas is Opening a New Free-Standing Emergency Room in Palm Harbor 2Health News:Florida Hospital North Pinellas is Opening a New Free-Standing Emergency Room in Palm Harbor 3
... The Mumbai-based Sun Pharmaceutical Industries entered the antismoking segment ... in Smoquit has been used for over a decade ... Rs. 13.50-per tablet priced Smoquit, the first pharmacotherapy ever ... prescription drug and is required to be taken under ...
... low testosterone levels in men suffering from eating ... affected more than women with the same problems, ... a weakening of the bones, which become dangerously thin ... and lack of essential nutrients, particularly calcium.Low bone mineral ...
... of proper nutrition while pregnant may be more likely to become ... from the University of Amsterdam looked at a group of 741 ... 1944-1945 which followed the Nazi occupation.// ,They found that ... when the study took place, was higher than in the general ...
... purple grape juice provides far greater antioxidant effects than ... journal of medicinal food. , The study states ... health through increased antioxidant consumption might prefer a glass ... juice," says Joe A. Vinson, professor of chemistry at ...
... men are at greater risk of developing heart disease than ... were published in the Archives of Internal Medicine, said they ... loss. ,The type of baldness also seemed to ... Those with frontal baldness had a 9% increased chance of ...
... supplement has been found to support immunity in elderly, ... every operation, rate of infection is a common risk, ... University of Pittsburgh report on the use of a ... undergoing surgery.// ,A group of 50 patients ...
Cached Medicine News:
(Date:8/27/2015)... India , August 27, 2015 According ... Product (Transfer, Hammock, Toilet, Seating, Universal, Standing, Bariatric ), Material (Nylon, ... - Forecast to 2020", published by MarketsandMarkets, the Medical Lifting Sling ... USD 411.5 Million in 2015, at a CAGR of 11.4 % ... 136 ma rket data T ables and ...
(Date:8/27/2015)... -- MiMedx Group, Inc. (NASDAQ: MDXG ), the ... and patent-protected processes to develop and market advanced ... Orthopedic, Spine, Sports Medicine, Ophthalmic and Dental sectors ... inaccuracies in the press release issued by the ... from the Patent Trial and Appeal Board ("PTAB"). ...
(Date:8/27/2015)... According to a new market ... Standalone), by Deployment Mode (Web based, On-Premise, Cloud-Based), by ... Providers), by Component - Global Trends & Forecast to ... at $501.1 Million 2014, and is projected to reach ... from 2014 to 2019. Browse 60 ...
Breaking Medicine Technology:Medical Lifting Sling Market Worth USD 706.0 Million by 2020 2Medical Lifting Sling Market Worth USD 706.0 Million by 2020 3Medical Lifting Sling Market Worth USD 706.0 Million by 2020 4MiMedx Corrects Inaccuracies In MTF Press Release Regarding The Recent Rulings From The Patent Trial And Appeal Board 2MiMedx Corrects Inaccuracies In MTF Press Release Regarding The Recent Rulings From The Patent Trial And Appeal Board 3MiMedx Corrects Inaccuracies In MTF Press Release Regarding The Recent Rulings From The Patent Trial And Appeal Board 4Radiology Information Systems Market Worth $722.7 Million by 2019 2Radiology Information Systems Market Worth $722.7 Million by 2019 3Radiology Information Systems Market Worth $722.7 Million by 2019 4
... CITY, Aug. 2, 2011 There is a company nestled ... Valley that is making strides in helping activate a usually ... Mind, creators of the eyeQ Speed Reading and Brain Enhancement ... Tech Pasadena and discovered astonishing results by measuring the difference ...
... Bio-Holdings, Ltd. - (OTCBB: HADSY), a publicly traded ... property developed and owned by Hadassah University Hospital, ... BioMarCare Technologies Ltd. ("BioMarCare") announced that the prestigious ... given initial approval for a $900,000 grant for ...
Cached Medicine Technology:Study Shows That Salt Lake City Based Company Has Program That Enhances Brain Activity 2BioMarCare Technologies Ltd. Receives a $900k Grant for a Joint Project with Ariadne Inc. 2BioMarCare Technologies Ltd. Receives a $900k Grant for a Joint Project with Ariadne Inc. 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: