Navigation Links
Severe alcoholic hepatitis: An effective combination of 2 treatments
Date:11/10/2011

Acute alcoholic hepatitis is one of the most serious forms of alcoholic liver disease, affecting individuals with chronic excessive alcohol consumption, which generally equates to more than 50 grams of alcohol per day (roughly five drinks), over a period of more than three to six months. The disease is characterized by liver failure (hepatic insufficiency) and acute jaundice (icterus), which may induce a coma through liver failure (hepatic encephalopathy) and an ensuing death rate of between 40-45% within the first six months. Conventional treatment involves stopping alcohol consumption (alcohol abstinence) and administering cortisone (corticosteroid therapy over a one-month period) to fight the highly inflammatory nature of the disease. Despite this treatment, 30-35% of patients with acute alcoholic hepatitis still die within a six month period, since the cortisone-based treatment remains insufficient.

Given the given the frequent deficiency in the antioxidant capacity of the alcoholic liver (described above), combined with chronic inflammation associated with the disease, the aim of the study coordinated by Professor Nguyen-Khas (Amiens University Hospital Centre and the Inserm research team) was to combine an antioxidant treatment with the conventional anti-inflammatory treatment. The results show an improved survival rate for patients suffering from acute alcoholic hepatitis who were given both medication types, with significantly less deaths within one month of treatment compared to the group who received the cortisone- only treatment. Tolerance levels to the treatment were good. The new, very low-cost medicine (N-acetylcysteine) is a molecule that has long been used in the treatment of hepatitis caused by drugs such as paracetamol, or mucolytic to fluidify bronchial secretion.

These results improve the prognosis for severe alcoholic hepatitis patients.


'/>"/>
Contact: Inserm Presse
presse@inserm.fr
INSERM (Institut national de la sant et de la recherche mdicale)
Source:Eurekalert

Page: 1

Related medicine news :

1. Imaging technique IDs plaques, tangles in brains of severely depressed older adults
2. Researchers identify potential risk factors for severe altitude sickness
3. Minority children less likely to wear a car seatbelt, putting them at greater risk of severe injury
4. Folic acid supplements in early pregnancy may reduce the risk of severe language delay in children
5. Oral steroids linked to severe vitamin D deficiency in nationwide study
6. HRT therapy appears to increase risk of hospitalization from severe asthma attacks
7. Vitamin D deficiency linked with airway changes in children with severe asthma
8. One-Third of Severe Heart Attack Patients Have Treatment Delays
9. Estrogen treatment may help reverse severe pulmonary hypertension
10. New Drug May Relieve Severe, Tough-to-Treat Gout
11. Anti-Clotting Drug May Cause Severe Bleeding With No Benefit
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... Viejo, California (PRWEB) , ... January 20, 2017 , ... ... easy to use inside of Final Cut Pro X," said Christina Austin - CEO ... on the RED Dragon. Utilizing the Dragon Sensor,TransFlare 4K Mystique lens flare and light ...
(Date:1/20/2017)... ... ... biographical account following a man who went on to support his country and serve the ... Lynn Haven, Florida and at the age of 5, his family moved to Pensacola Florida. ... Navy and got married right out of boot camp. , He and his wife ...
(Date:1/20/2017)... ... January 20, 2017 , ... “Journey to Christmas:” a beautiful and enchanting tale that ... author, Kimberly Cordoves, a mother of three in Oklahoma City, and a devoted woman of ... writing a book has been in the back of my mind for years, but actually ...
(Date:1/19/2017)... ... 20, 2017 , ... Today, the Centers for Medicare & Medicaid Services (CMS) ... Payment Models (APMs) in 2017. Clinicians who participate in APMs are paid for the ... of the Administration’s effort to build a system that delivers better care and one ...
(Date:1/19/2017)... , ... January 19, 2017 , ... With the cold weather here, many people will ... blowers are efficient when clearing large amounts of snow, but they can be dangerous when ... U.S. Consumer Product Safety Commission for the proper use of snow blowers:, ...
Breaking Medicine News(10 mins):
(Date:1/20/2017)... -- Wells Specialty Pharmacy announces the acquisitions and merger of ... Winter Park, Florida and Pharm-EZ Medical, LLC, ... been consolidated into the 3796 Howell Branch Road Facility. ... Chad Tomlinson , former Vice President of Operations, has ... Tomlinson is a Graduate of Florida State University and has ...
(Date:1/19/2017)... , Jan. 19, 2017 ... Summary GlobalData,s new report, "Germany Cataract Surgery Devices ... the Germany Cataract Surgery Devices market. The report provides ... and average prices (USD) within market segements - Phacoemulsification ... also provides company shares and distribution shares data for ...
(Date:1/19/2017)... The Global Therapy Partnering Terms and Agreements ... deals and agreements entered into by the world,s leading ... Top deals by value - Deals listed by company ... The report provides understanding and access to the partnering ... healthcare companies. The report provides an analysis of ...
Breaking Medicine Technology: