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Severe acute kidney injuries rise rapidly nationwide
Date:12/6/2012

is largely a silent one, because the organ itself is so redundant in structure and steadfast in function, according to Chi-yuan Hsu, MD, who is chief of the Division of Nephrology in the UCSF School of Medicine and senior author on the paper. Composed of more than a million identical structures called nephrons, which filter blood and produce urine, a single kidney can function even if a large part of it is damaged or shut down.

"Even if you were to lose 80 percent of your kidney function, you wouldn't feel it," said Chi-yuan Hsu, who is not related to Raymond Hsu. But once the insult to the kidneys becomes severe enough to require a patient to go on dialysis, he said, the result is often fatal about one-fifth of patients with acute kidney injury requiring dialysis in the study died.

Analyzing a decade's worth of data and coming up with national statistics on acute kidney injury is a first step towards discovering why this condition has been steadily rising and developing measures to prevent them in the future, the UCSF team said.

"We hope that clinicians, researchers and the general public can gain a higher appreciation of the devastating impact of acute kidney injury that is comparable to the near universal, basic understanding of other forms of acute organ injury, such as heart attack and stroke," Raymond Hsu said.


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Contact: Jason Socrates Bardi
jason.bardi@ucsf.edu
415-502-4608
University of California - San Francisco
Source:Eurekalert  

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