Navigation Links
Severe Health Risks Follow Adults Who Were Diagnosed With Nonalcoholic Fatty Liver Disease as Children
Date:10/28/2008

Research to be presented Sunday, November 2, 2008 at this year's liver

meeting in San Francisco, California, October 31 - November 4

SAN FRANCISCO, Oct. 28 /PRNewswire/ -- The goal of researchers from the Mayo Clinic in Rochester, MN, led by Dr. Paul Angulo, was to determine the effects of fatty liver disease in children up to 20 years after the initial diagnosis. This is especially important as nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver disease in preadolescents and adolescents. To put the problem of NAFLD into perspective, Ariel Feldstein, MD, another investigator involved with the study said, "In the past ten years, the rate of obesity in our country has tripled in children and teenagers, and this most likely explains why NAFLD is becoming so common. Some experts estimate that about half of obese children may have fatty liver disease."

The authors identified 66 children who were diagnosed with NAFLD and had extensive follow up data available for review. After the initial diagnosis, four children developed type 2 diabetes and four children had increased liver fibrosis. During follow up two children developed end-stage liver disease and required a liver transplantation. However NAFLD recurred in the transplanted liver in the two cases, with one case progressing to cirrhosis and requiring re-transplantation. The study demonstrated that NAFLD in children is associated with a significantly shorter long-term survival as compared to the expected survival of the general population. Children with NAFLD had an almost 14-fold higher risk of dying or requiring liver transplantation than the general population of same age and sex.

"There is currently no medication proven to be effective for NAFLD," development of medications that could treat NAFLD and NASH is an area of intense research," said Dr. Feldstein, "and it remains unclear whether there are any clinical or laboratory features that can be used to identify the subgroup of children with NAFLD that will develop advanced liver disease later in life."

"The most important recommendations for children with fatty liver are to lose weight if they are overweight or obese, increase their physical activity, follow a balanced diet and avoid unnecessary medications," concluded Dr. Feldstein.

Abstract title:

The natural history of nonalcoholic fatty liver disease in children: A follow-up study up to 20 years.

AASLD is the leading medical organization for advancing the science and practice of hepatology. Founded by physicians in 1950, AASLD's vision is to prevent and cure liver diseases. This year's Liver Meeting, held in San Francisco, California, October 31 - November 4, will bring together more than 7,000 researchers from 55 countries.

A pressroom will be available from November 1 at the annual meeting. For copies of abstracts and press releases, or to arrange for pre-conference research interviews contact Gregory Bologna at 703-299-9766. To pre-register, call Ann Tracy at 703-299-9766.

Press releases and all abstracts are available online at http://www.aasld.org .

This release was issued through The Xpress Press News Service, merging e-mail and satellite distribution technologies to reach business analysts and media outlets worldwide. For more information, visit http://www.XpressPress.com


'/>"/>
SOURCE American Association for the Study of Liver Diseases
Copyright©2008 PR Newswire.
All rights reserved

Related medicine news :

1. Enbrel(R) (etanercept) Is the First Biologic With Published Efficacy and Safety Data for up to a Decade of Continuous Use for the Treatment of Moderate to Severe Rheumatoid Arthritis
2. SEAL Indiana Reports More Than Half of Indianapolis Area School Kids Treated by Program Have Moderate or Severe Dental Decay
3. A little exercise goes a long way for severely obese
4. Potential treatment option for severe emphysema under study
5. Out of Iraq emerges hope for those with the severest of head injuries
6. Strategies for preventing gastrointestinal complications in severely burned patients
7. Kids Eye Injuries From Golf Clubs Rare But Severe
8. UNC trial: oral contraceptives may ease suffering of women with severe PMS
9. UNC study: Two-thirds of severe sports injuries to female students due to cheerleading
10. Note to people with scarred and stiffened lungs: Monitor your sleep before severe fatigue sets in
11. Vaccinated infants well-protected against severe pneumococcal infection in Norway
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/13/2016)... Memphis, Tennessee (PRWEB) , ... February 13, 2016 ... ... Practice, the Infusion Nurses Society (INS) states that vein visualization technology should be ... used by healthcare facilities around the world, the INS Standards mandate the use ...
(Date:2/13/2016)... ... , ... In the early or “honeymoon” stage of a relationship, couples strive ... their way to be romantic, and may exaggerate a strength or two in an ... profile. , A recent study from Queendom.com , however, suggests that new ...
(Date:2/12/2016)... ... 12, 2016 , ... Mystic Buddha Publishing House presents Valentine’s Day tips on ... of Rama - Dr. Frederick Lenz. , According to Publisher Roger Cantu, ... teacher for teaching and helping others. Valentine’s Day celebrates love in all its ...
(Date:2/12/2016)... , ... February 12, 2016 , ... ... devoted exclusively to funding innovative lymphoma research and serving the lymphoma community through ... over 250 members of South Florida’s philanthropic community at its 10th anniversary Fashion ...
(Date:2/12/2016)... ... February 12, 2016 , ... Each year, the American Physical Therapy ... Anaheim, CA at the Anaheim Convention Center. Almost 10,000 physical therapists across the country ... in action, learn more about their chosen field and network with their colleagues. ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... Feb. 12, 2016 On Thursday, Feb. 11, ... at St. David,s North Austin Medical Center successfully completed ... Xi ® Surgical System with Trumpf Medical,s ... Thiru Lakshman , M.D., colorectal surgeon at the ... utilizing Integrated Table Motion technology, which seamlessly combines the ...
(Date:2/12/2016)... BUFORD, Ga. , Feb. 12 2016  OMS ... office-based dental and medical practitioners, announced today the recent ... website offers visitors a variety of features that enhance ... purchase oral surgery supplies. --> ... Supply is a fairly new company that started in ...
(Date:2/12/2016)... , Maharashtra, February 12, 2016 ... Market research report titled Chronic Inflammation Global Clinical ... a snapshot of the global clinical trials landscape ... clinical trials by Region, Country (G7 & E7), ... point status and reviews top companies involved and ...
Breaking Medicine Technology: