Navigation Links
Severe Health Risks Follow Adults Who Were Diagnosed With Nonalcoholic Fatty Liver Disease as Children
Date:10/28/2008

Research to be presented Sunday, November 2, 2008 at this year's liver

meeting in San Francisco, California, October 31 - November 4

SAN FRANCISCO, Oct. 28 /PRNewswire/ -- The goal of researchers from the Mayo Clinic in Rochester, MN, led by Dr. Paul Angulo, was to determine the effects of fatty liver disease in children up to 20 years after the initial diagnosis. This is especially important as nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver disease in preadolescents and adolescents. To put the problem of NAFLD into perspective, Ariel Feldstein, MD, another investigator involved with the study said, "In the past ten years, the rate of obesity in our country has tripled in children and teenagers, and this most likely explains why NAFLD is becoming so common. Some experts estimate that about half of obese children may have fatty liver disease."

The authors identified 66 children who were diagnosed with NAFLD and had extensive follow up data available for review. After the initial diagnosis, four children developed type 2 diabetes and four children had increased liver fibrosis. During follow up two children developed end-stage liver disease and required a liver transplantation. However NAFLD recurred in the transplanted liver in the two cases, with one case progressing to cirrhosis and requiring re-transplantation. The study demonstrated that NAFLD in children is associated with a significantly shorter long-term survival as compared to the expected survival of the general population. Children with NAFLD had an almost 14-fold higher risk of dying or requiring liver transplantation than the general population of same age and sex.

"There is currently no medication proven to be effective for NAFLD," development of medications that could treat NAFLD and NASH is an area of intense research," said Dr. Feldstein, "and it remains unclear whether there are any clinical or laboratory features that can be used to identify the subgroup of children with NAFLD that will develop advanced liver disease later in life."

"The most important recommendations for children with fatty liver are to lose weight if they are overweight or obese, increase their physical activity, follow a balanced diet and avoid unnecessary medications," concluded Dr. Feldstein.

Abstract title:

The natural history of nonalcoholic fatty liver disease in children: A follow-up study up to 20 years.

AASLD is the leading medical organization for advancing the science and practice of hepatology. Founded by physicians in 1950, AASLD's vision is to prevent and cure liver diseases. This year's Liver Meeting, held in San Francisco, California, October 31 - November 4, will bring together more than 7,000 researchers from 55 countries.

A pressroom will be available from November 1 at the annual meeting. For copies of abstracts and press releases, or to arrange for pre-conference research interviews contact Gregory Bologna at 703-299-9766. To pre-register, call Ann Tracy at 703-299-9766.

Press releases and all abstracts are available online at http://www.aasld.org .

This release was issued through The Xpress Press News Service, merging e-mail and satellite distribution technologies to reach business analysts and media outlets worldwide. For more information, visit http://www.XpressPress.com


'/>"/>
SOURCE American Association for the Study of Liver Diseases
Copyright©2008 PR Newswire.
All rights reserved

Related medicine news :

1. Enbrel(R) (etanercept) Is the First Biologic With Published Efficacy and Safety Data for up to a Decade of Continuous Use for the Treatment of Moderate to Severe Rheumatoid Arthritis
2. SEAL Indiana Reports More Than Half of Indianapolis Area School Kids Treated by Program Have Moderate or Severe Dental Decay
3. A little exercise goes a long way for severely obese
4. Potential treatment option for severe emphysema under study
5. Out of Iraq emerges hope for those with the severest of head injuries
6. Strategies for preventing gastrointestinal complications in severely burned patients
7. Kids Eye Injuries From Golf Clubs Rare But Severe
8. UNC trial: oral contraceptives may ease suffering of women with severe PMS
9. UNC study: Two-thirds of severe sports injuries to female students due to cheerleading
10. Note to people with scarred and stiffened lungs: Monitor your sleep before severe fatigue sets in
11. Vaccinated infants well-protected against severe pneumococcal infection in Norway
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... , ... PawPaws brand pet supplements owned by Whole Health Supply ... health of felines. The formula is all-natural and is made from Chinese herbs that ... Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root ...
(Date:6/25/2016)... ... , ... The temporary closing of Bruton Memorial Library on June 21 due to a possible ... often overlooked aspect of head lice: the parasite’s ability to live away from a human ... but a necessary one in the event that lice have simply gotten out of control. ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of ... recognition of their exemplary accomplishments in worksite health promotion. , The Wellness at Work ... Symposium at the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses ...
(Date:6/24/2016)... ... , ... Marcy was in a crisis. Her son James, eight, was out of control. Prone ... physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If ... at my other children and say he was going to kill them. If we ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, ... minimum wage raise to $12 an hour by 2020 and then adjusting it yearly to ... value of the minimum wage, assure the wage floor does not erode again, and make ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... SOUTH SAN FRANCISCO, Calif. , June 24, ... GBT ), a biopharmaceutical company developing novel ... with significant unmet needs, today announced the closing ... 6,400,000 shares of common stock, at the public ... the shares in the offering were offered by ...
(Date:6/24/2016)... BEIJING , June 24, 2016 Dehaier ... or the "Company"), which develops, markets and sells medical ... China , signed a strategic cooperation agreement with ... as "Hongyuan Supply Chain") on June 20, 2016, to ... Under the strategic cooperation agreement, Dehaier will leverage Hongyuan ...
(Date:6/24/2016)... , June 24, 2016 VolitionRx ... of Dr. Edward Futcher to the ... effective June 23, 2016.Dr. Futcher was also appointed ... Governance Committees.  As a non-executive member of the ... and strategic counsel to VolitionRx in connection with ...
Breaking Medicine Technology: