Navigation Links
Severe Health Risks Follow Adults Who Were Diagnosed With Nonalcoholic Fatty Liver Disease as Children
Date:10/28/2008

Research to be presented Sunday, November 2, 2008 at this year's liver

meeting in San Francisco, California, October 31 - November 4

SAN FRANCISCO, Oct. 28 /PRNewswire/ -- The goal of researchers from the Mayo Clinic in Rochester, MN, led by Dr. Paul Angulo, was to determine the effects of fatty liver disease in children up to 20 years after the initial diagnosis. This is especially important as nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver disease in preadolescents and adolescents. To put the problem of NAFLD into perspective, Ariel Feldstein, MD, another investigator involved with the study said, "In the past ten years, the rate of obesity in our country has tripled in children and teenagers, and this most likely explains why NAFLD is becoming so common. Some experts estimate that about half of obese children may have fatty liver disease."

The authors identified 66 children who were diagnosed with NAFLD and had extensive follow up data available for review. After the initial diagnosis, four children developed type 2 diabetes and four children had increased liver fibrosis. During follow up two children developed end-stage liver disease and required a liver transplantation. However NAFLD recurred in the transplanted liver in the two cases, with one case progressing to cirrhosis and requiring re-transplantation. The study demonstrated that NAFLD in children is associated with a significantly shorter long-term survival as compared to the expected survival of the general population. Children with NAFLD had an almost 14-fold higher risk of dying or requiring liver transplantation than the general population of same age and sex.

"There is currently no medication proven to be effective for NAFLD," development of medications that could treat NAFLD and NASH is an area of intense research," said Dr. Feldstein, "and it remains unclear whether there are any clinical or laboratory features that can be used to identify the subgroup of children with NAFLD that will develop advanced liver disease later in life."

"The most important recommendations for children with fatty liver are to lose weight if they are overweight or obese, increase their physical activity, follow a balanced diet and avoid unnecessary medications," concluded Dr. Feldstein.

Abstract title:

The natural history of nonalcoholic fatty liver disease in children: A follow-up study up to 20 years.

AASLD is the leading medical organization for advancing the science and practice of hepatology. Founded by physicians in 1950, AASLD's vision is to prevent and cure liver diseases. This year's Liver Meeting, held in San Francisco, California, October 31 - November 4, will bring together more than 7,000 researchers from 55 countries.

A pressroom will be available from November 1 at the annual meeting. For copies of abstracts and press releases, or to arrange for pre-conference research interviews contact Gregory Bologna at 703-299-9766. To pre-register, call Ann Tracy at 703-299-9766.

Press releases and all abstracts are available online at http://www.aasld.org .

This release was issued through The Xpress Press News Service, merging e-mail and satellite distribution technologies to reach business analysts and media outlets worldwide. For more information, visit http://www.XpressPress.com


'/>"/>
SOURCE American Association for the Study of Liver Diseases
Copyright©2008 PR Newswire.
All rights reserved

Related medicine news :

1. Enbrel(R) (etanercept) Is the First Biologic With Published Efficacy and Safety Data for up to a Decade of Continuous Use for the Treatment of Moderate to Severe Rheumatoid Arthritis
2. SEAL Indiana Reports More Than Half of Indianapolis Area School Kids Treated by Program Have Moderate or Severe Dental Decay
3. A little exercise goes a long way for severely obese
4. Potential treatment option for severe emphysema under study
5. Out of Iraq emerges hope for those with the severest of head injuries
6. Strategies for preventing gastrointestinal complications in severely burned patients
7. Kids Eye Injuries From Golf Clubs Rare But Severe
8. UNC trial: oral contraceptives may ease suffering of women with severe PMS
9. UNC study: Two-thirds of severe sports injuries to female students due to cheerleading
10. Note to people with scarred and stiffened lungs: Monitor your sleep before severe fatigue sets in
11. Vaccinated infants well-protected against severe pneumococcal infection in Norway
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... ... April 28, 2017 , ... Horizon Blue Cross Blue Shield of ... rating of “A” and its outlook as “stable.” At the same time, the ratings ... fallen in recent years, dip below “capital adequacy” thresholds required for its strong rating. ...
(Date:4/28/2017)... ... April 28, 2017 , ... Ushio ... These lamps offer an instant energy-saving solution for F32T8 fluorescent lamps on most ... disconnect ballasts. These 50,000 hour rated lamps utilize the existing electronic ballast, saving ...
(Date:4/28/2017)... ... April 28, 2017 , ... The Texas Cord Blood Bank (TCBB), a ... and delivery team at Women’s Hospital at Renaissance in Edinburg for their outstanding efforts ... hospital and decide to donate. , “Women’s Hospital at Renaissance has been a ...
(Date:4/28/2017)... ... 28, 2017 , ... Bill Howe started his sewer and drain company in ... Howe joined the team, the Bill Howe brand was born and they began cultivating ... giving back to the San Diego community in which they worked, lived and were ...
(Date:4/28/2017)... ... April 28, 2017 , ... ... assisting the Brooke Grove Foundation implement a Microsoft Dynamics GP solution that integrates ... leading ERP expert that specializes in long-term care, Brooke Grove now has the ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... -- Vivify Health, the pioneer and market leader of remote ... significant patent for the advancement of healthcare delivery from ... health.  This landmark patent provides the company with broad ... position as the leader in remote care.  ... to apply consumer mobile devices, wireless biometrics, EMR integration ...
(Date:4/20/2017)... 20, 2017 Research and Markets has announced ... Driven by Rapidly Expanding Injectables Market and Increasing Usage of Complex ... ... technologies will rise from USD 20 Billion in 2015 to around ... Delivery Technologies - Innovation Driven by Rapidly Expanding Injectables Market and ...
(Date:4/20/2017)... April 20, 2017 Research and Markets ... Size, Market Share, Application Analysis, Regional Outlook, Growth Trends, Key ... to their offering. ... global pharmacogenomics market was valued at US$ 7,167.6 Mn in ... 2024, expanding at a CAGR of 5.6% from 2016 to ...
Breaking Medicine Technology: