Navigation Links
Several genes that regulate the disease SLE have been identified

Swedish researchers, in collaboration with foreign colleagues, have identified a number of new genes that can be tied to the disease SLE, including a gene that hopefully might be used to treat the disease in the future by regulating the production of antibodies. These unique findings are being published in three articles in the new issue of the journal Nature Genetics.

SLE (systemic lupus erythematosus) is a so-called autoimmune disease, meaning that the immune defense system attacks the body. SLE primarily affects young women and can lead to severe kidney failure, blood clots, and miscarriages, among other things.

A research team at Uppsala University directed by Associate Professor Marta E. Alarcn-Requelme has identified a new gene, BANK1, that is important to our understanding of how SLE arises and that may also come to be of significance for treatment. The gene affects the bodys B cells, which in turn produce the auto-antibodies that attack the body.

The new treatments of SLE that have been developed primarily target the elimination of B cells. With the help of the gene we have now identified, in the future it may be possible to regulate the functions of B cells, says Marta E. Alarcn-Requelme.

Moreover, her research team, working together with American and British colleagues, has performed a complete scan of the genome of 1,800 European and American SLE patients and thereby managed to identify a number of other genes that regulate the disease. All of these findings are now being published in three separate articles in the February issue of the scientific journal Nature Genetics and are already available in the Web version of the journal.


Contact: Johanna Blomqvist
Uppsala University

Page: 1

Related medicine news :

1. Forest Laboratories, Inc. and Merz Pharma GmbH & Co. KgaA File Lawsuits Against Several Companies for Patent Infringement
2. Wyeth Consumer Healthcare Initiates Voluntary Recall and Replacement Program for Several Robitussin Products and Childrens Dimetapp Cold & Chest Congestion
3. Announces Corporate Sponsorships with Several of the Nations Leading Health Charities
4. Governor Rendell Announces CHIP Enrollment Clinics at Several Rite Aid Stores
5. New Batch of Lupus Genes Discovered
6. Scientists identify genes linked to lupus in women
7. Genes Linked to Height Also Tied to Osteoarthritis Risk
8. Evidence found for genes that affect risk of developing Alzheimers disease
9. Childrens Hospital Boston Mourns the Death of Dr. Judah Folkman, World Renowned Researcher and Founder of the Field of Angiogenesis
10. Seven New Cholesterol Genes Discovered
11. Team Finds 118 Genes That Might Play Role in Cancer
Post Your Comments:
(Date:11/30/2015)... ... ... According to research by the National Association of Dental ... certified or obtain continuing education. To increase awareness of the lack of standards ... inform dentists that the technicians they trust could lack the skills and knowledge ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... The directory is specialized and only includes chiropractic clinics in the US. , ... and trustworthy alternative health practitioner when back pain sets in. When people are ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... experience this summer, ushering in a new era of publicly accessible automated technology. ... shuttle, will continue to offer guests an up-close look at the shuttle at ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... for Halloween festivities, the Word of Life Christian Church of Flint, MI, hosted ... featuring a giant 1.25 ton pile of candy dubbed “Candy Mountain”. , A ...
(Date:11/30/2015)... ... November 30, 2015 , ... In an effort ... to access life-saving information provided directly from top experts in mesothelioma, in ... individual conferences in three major cities: Houston, San Francisco, and Chicago. , ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... Die MEDTEC Japan 2016, ... Entwicklung und Herstellung medizinischer Geräte, findet ... in Tokyo ... Foto: ... --> ...
(Date:11/30/2015)... , Nov. 30, 2015 Nevro Corp. (NYSE: ... providing innovative evidence-based solutions for the treatment of chronic pain, ... at the U.S. Patent and Trademark Office (USPTO) has denied ... Patent No. 8,359,102 (the ,102 patent).  ... unit of Boston Scientific Corporation filed two petitions challenging the ...
(Date:11/30/2015)... , Nov. 30, 2015   Royal ... announced the launch of Radiology Solutions, a fully ... Radiology Solutions comprises customized, data-driven practice management approaches ... to help radiology practices improve care delivery and ... 2015 Radiological Society of North America Annual Meeting ...
Breaking Medicine Technology: