Navigation Links
Several genes that regulate the disease SLE have been identified
Date:1/22/2008

Swedish researchers, in collaboration with foreign colleagues, have identified a number of new genes that can be tied to the disease SLE, including a gene that hopefully might be used to treat the disease in the future by regulating the production of antibodies. These unique findings are being published in three articles in the new issue of the journal Nature Genetics.

SLE (systemic lupus erythematosus) is a so-called autoimmune disease, meaning that the immune defense system attacks the body. SLE primarily affects young women and can lead to severe kidney failure, blood clots, and miscarriages, among other things.

A research team at Uppsala University directed by Associate Professor Marta E. Alarcn-Requelme has identified a new gene, BANK1, that is important to our understanding of how SLE arises and that may also come to be of significance for treatment. The gene affects the bodys B cells, which in turn produce the auto-antibodies that attack the body.

The new treatments of SLE that have been developed primarily target the elimination of B cells. With the help of the gene we have now identified, in the future it may be possible to regulate the functions of B cells, says Marta E. Alarcn-Requelme.

Moreover, her research team, working together with American and British colleagues, has performed a complete scan of the genome of 1,800 European and American SLE patients and thereby managed to identify a number of other genes that regulate the disease. All of these findings are now being published in three separate articles in the February issue of the scientific journal Nature Genetics and are already available in the Web version of the journal.


'/>"/>

Contact: Johanna Blomqvist
johanna.blomqvist@uadm.uu.se
46-704-250-864
Uppsala University
Source:Eurekalert

Page: 1

Related medicine news :

1. Forest Laboratories, Inc. and Merz Pharma GmbH & Co. KgaA File Lawsuits Against Several Companies for Patent Infringement
2. Wyeth Consumer Healthcare Initiates Voluntary Recall and Replacement Program for Several Robitussin Products and Childrens Dimetapp Cold & Chest Congestion
3. RxPop.com Announces Corporate Sponsorships with Several of the Nations Leading Health Charities
4. Governor Rendell Announces CHIP Enrollment Clinics at Several Rite Aid Stores
5. New Batch of Lupus Genes Discovered
6. Scientists identify genes linked to lupus in women
7. Genes Linked to Height Also Tied to Osteoarthritis Risk
8. Evidence found for genes that affect risk of developing Alzheimers disease
9. Childrens Hospital Boston Mourns the Death of Dr. Judah Folkman, World Renowned Researcher and Founder of the Field of Angiogenesis
10. Seven New Cholesterol Genes Discovered
11. Team Finds 118 Genes That Might Play Role in Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... As health professionals work to improve ... engagement.” The patient is doing more than filling out a survey; in many cases ... an increasing emphasis in health care and research on the importance of active engagement ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical ... the primary prevention of cardiovascular diseases during the 15th Annual Women’s Health ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional ... action towards gender equality at their inaugural Summit in New York City in June. ... a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... , ... October 13, 2017 , ... “The Journey: From ... every danger possible to save lost souls in the Philippines. “The Journey: From the ... is a dedicated teacher of the Bible. She has taught all ages and currently ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... the demand of today’s consumer and regulatory authorities worldwide. From Children’s to Adults ... tested to meet the highest standard. , These products are also: Gluten ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... and NEW YORK , Sept. 27, 2017  DarioHealth ... and big data solutions, today announced that its MyDario product is expected ... local TV listings for when The Dr. Oz Show airs in your ... The nine-time Emmy ... ...
(Date:9/22/2017)... -- AVACEN Medical (AVACEN) announced that its CE-Marked AVACEN ... with the widespread pain associated with fibromyalgia in the ... Essex, England commented, "I had difficulty ... sleep at all, tremendous pain, with every movement sending ... AVACEN 100] enough, how this has and is helping ...
(Date:9/13/2017)... Sept. 13, 2017   OrthoAtlanta has been named ... Football Host Committee (AFHC) for the 2018 College Football Playoff ... 2018, at Mercedes-Benz Stadium in Atlanta, Georgia ... AFHC "I,m In" campaign, participating in many activities leading up ... ...
Breaking Medicine Technology: