Navigation Links
Several genes that regulate the disease SLE have been identified

Swedish researchers, in collaboration with foreign colleagues, have identified a number of new genes that can be tied to the disease SLE, including a gene that hopefully might be used to treat the disease in the future by regulating the production of antibodies. These unique findings are being published in three articles in the new issue of the journal Nature Genetics.

SLE (systemic lupus erythematosus) is a so-called autoimmune disease, meaning that the immune defense system attacks the body. SLE primarily affects young women and can lead to severe kidney failure, blood clots, and miscarriages, among other things.

A research team at Uppsala University directed by Associate Professor Marta E. Alarcn-Requelme has identified a new gene, BANK1, that is important to our understanding of how SLE arises and that may also come to be of significance for treatment. The gene affects the bodys B cells, which in turn produce the auto-antibodies that attack the body.

The new treatments of SLE that have been developed primarily target the elimination of B cells. With the help of the gene we have now identified, in the future it may be possible to regulate the functions of B cells, says Marta E. Alarcn-Requelme.

Moreover, her research team, working together with American and British colleagues, has performed a complete scan of the genome of 1,800 European and American SLE patients and thereby managed to identify a number of other genes that regulate the disease. All of these findings are now being published in three separate articles in the February issue of the scientific journal Nature Genetics and are already available in the Web version of the journal.


Contact: Johanna Blomqvist
Uppsala University

Page: 1

Related medicine news :

1. Forest Laboratories, Inc. and Merz Pharma GmbH & Co. KgaA File Lawsuits Against Several Companies for Patent Infringement
2. Wyeth Consumer Healthcare Initiates Voluntary Recall and Replacement Program for Several Robitussin Products and Childrens Dimetapp Cold & Chest Congestion
3. Announces Corporate Sponsorships with Several of the Nations Leading Health Charities
4. Governor Rendell Announces CHIP Enrollment Clinics at Several Rite Aid Stores
5. New Batch of Lupus Genes Discovered
6. Scientists identify genes linked to lupus in women
7. Genes Linked to Height Also Tied to Osteoarthritis Risk
8. Evidence found for genes that affect risk of developing Alzheimers disease
9. Childrens Hospital Boston Mourns the Death of Dr. Judah Folkman, World Renowned Researcher and Founder of the Field of Angiogenesis
10. Seven New Cholesterol Genes Discovered
11. Team Finds 118 Genes That Might Play Role in Cancer
Post Your Comments:
(Date:6/24/2016)... ... 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. In ... benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued ... Sickle Cell Disease (SCD) is a disorder of the red blood cells, which can ...
(Date:6/24/2016)... Fla. (PRWEB) , ... June 24, 2016 , ... Global ... Trend magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this recognition ... Florida. , Seven Greenberg Traurig Shareholders received special honors as members of this year’s ...
(Date:6/24/2016)... ... ... of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair Minimum Wage’ ... 2020 and then adjusting it yearly to increase at the same rate as the median ... floor does not erode again, and make future increases more predictable. , The company is ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... proud to recognize Dr. Barry M. Weintraub as a prominent plastic surgeon and ... women in the world, and the most handsome men, look naturally attractive. Plastic ...
(Date:6/24/2016)... ... June 24, 2016 , ... National recruitment firm Slone Partners ... with extensive sequencing and genomics experience, as Vice President of North American Capital Sales ... be responsible for leading the sales team in the commercialization of the HTG EdgeSeq ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Mass. , June 24, 2016   Pulmatrix, ... pharmaceutical company developing innovative inhaled drugs, announced today that ... Russell Investments reconstituted its comprehensive set of ... "This is an important milestone for Pulmatrix," ... will increase shareholder awareness of our progress in developing ...
(Date:6/23/2016)... June 23, 2016  MedSource announced today that ... e-clinical software solution of choice.  This latest decision ... value to their clients by offering a state-of-the-art ... relationship establishes nowEDC as the EDC platform of ... full-service clients.  "nowEDC has long been a preferred ...
(Date:6/23/2016)... -- Research and Markets has announced the ... (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality (Filler, ... Global Forecast to 2021" report to their offering. ... pharmaceutical excipients market is projected to reach USD 8.1 ... the forecast period 2016 to 2021. ...
Breaking Medicine Technology: