Navigation Links
Seven New Cholesterol Genes Discovered
Date:1/13/2008

Study finds only those that regulate LDL levels influence heart disease risk

SUNDAY, Jan. 13 (HealthDay News) -- Seven new cholesterol-regulating genes, some of which influence the risk of heart disease, have been identified in an international study of almost 20,000 people in three countries.

"I would predict that some of these genes will be the targets for future drugs," said the study's senior author, Goncalo Abecasis, an associate professor of biostatistics at the University of Michigan School of Public Health.

In their report, published in the Jan. 13 issue of Nature Genetics., the researchers also confirmed the role of 11 previously identified cholesterol-related genes in the risk of heart disease.

"What was most exciting was that only the genetic changes that affect LDL cholesterol influence the risk of heart disease," Abecasis said. "Every genetic change that raises the level of LDL cholesterol influences the risk of heart disease."

LDL cholesterol is well known to be the "bad" kind that forms plaques that eventually can block arteries, causing heart attacks and other cardiovascular troubles. LDL cholesterol is the target of statins, drugs given to reduce coronary risk. HDL cholesterol is the "good" kind, which does not contribute to plaque formation.

"The conventional wisdom is that HDL cholesterol is good for you," Abecasis said. "But in our studies we found no major impact from those genes changing HDL cholesterol levels."

The research, done in collaboration with University of North Carolina and Harvard University researchers, started with genetic studies of 8,800 people from Italy, Sweden and Finland.

The researchers examined more than 2 million genetic variations in those individuals, eventually concentrating on 25 genetic variants, which together are responsible for about 25 percent of levels of blood lipids such as cholesterol.

The study asso
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Health Level Seven Appoints John Quinn as CTO
2. AMERIGROUP Contracts with Federal Government to Offer Medicare Advantage Health Plans in Seven States
3. Kaiser Permanente Study Shows One in Seven Women are Depressed Before, During, or After Pregnancy
4. Hospital Corporation of America Purchases Seventh CyberKnife(R) System
5. Seven Finalists Announced for 2007 Insight Award for Customer Advocacy in Healthcare
6. New Poll Finds Nearly Seven in 10 New Jersey Voters Support Smoke-Free Casinos
7. President Musevenis Visit Protested by HIV/AIDS Experts
8. HealthPartners is National Benchmark in Six Out of Seven Areas in National Business Coalition on Health Report
9. CNN Honors Extraordinary Deeds of Seven Everyday People in Global Event
10. Medifast, Inc. Receives Approval to Sell Medifast Weight Control Centers Franchises in Seven Additional States
11. Seven Community Service Organizations Granted Over $60,000 From Delta Dental Of Illinois
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Seven New Cholesterol Genes Discovered
(Date:7/28/2014)... July 28, 2014 Ticket Down ... Roma tickets in Dallas, TX at the Cotton Bowl. ... in the USA and it is an eight team tourney. ... the world including teams from La Liga, Serie A, English ... will battle it out on the pitch include: Manchester ...
(Date:7/28/2014)... Ticket Down is a dependable source ... FL at the Sun Life Stadium in early September. ... and Brazil has is one that has continues to go ... forming on a consistent basis. The rivalry between South ... the recent 2014 World Cup. To the delight of ...
(Date:7/28/2014)... Steven Reinberg HealthDay Reporter ... dementia and heart rhythm irregularities are more likely to get ... In fact, the study of more than 16,000 people ... more likely to get a pacemaker than those without the ... is why folks with dementia are so much more likely ...
(Date:7/28/2014)... York, NY (PRWEB) July 28, 2014 ... literacy organization that has donated more than 200,000 books ... in 2001, announces the launch of Brooke’s Cooks, a ... values, while encouraging healthy living among at-risk children and ... Cooks will include a series of nutrition information workshops, ...
(Date:7/28/2014)... July 28, 2014 UT Southwestern Medical Center ... and irreversibly interferes with the activity of a ... tumors. , The molecule, SML-8-73-1 (SML), interferes with ... oncogene homolog. The gene produces proteins called K-Ras ... can result in normal cells dividing uncontrollably and ...
Breaking Medicine News(10 mins):Health News:Real Madrid vs. AS Roma Tickets Cotton Bowl Dallas, TX: Ticket Down Cuts Ticket Prices for AS Roma vs. Real Madrid International Champions Cup Tickets 2Health News:Real Madrid vs. AS Roma Tickets Cotton Bowl Dallas, TX: Ticket Down Cuts Ticket Prices for AS Roma vs. Real Madrid International Champions Cup Tickets 3Health News:Brazil vs. Colombia Tickets in Miami: Ticket Down Slashes Colombia vs. Brazil Tickets at Sun Life Stadium in Miami for Sept. 5th Showdown 2Health News:Brazil vs. Colombia Tickets in Miami: Ticket Down Slashes Colombia vs. Brazil Tickets at Sun Life Stadium in Miami for Sept. 5th Showdown 3Health News:Pacemakers Common for Those With Dementia and Irregular Heartbeats 2Health News:Pacemakers Common for Those With Dementia and Irregular Heartbeats 3Health News:Brooke Jackman Foundation Launches Brooke's Cooks, New Initiative to Promote Healthy Living Among At-Risk Youth and Their Families 2Health News:Brooke Jackman Foundation Launches Brooke's Cooks, New Initiative to Promote Healthy Living Among At-Risk Youth and Their Families 3Health News:Brooke Jackman Foundation Launches Brooke's Cooks, New Initiative to Promote Healthy Living Among At-Risk Youth and Their Families 4Health News:UTSW cancer researchers identify irreversible inhibitor for KRAS gene mutation 2
... Online Science Writers Webinar , NCI and ASCO will ... Wide Web that will explore key issues surrounding cancer ... experts from the United States, Africa, Asia and India ... Incidence, Survival and Mortality Trends , The State ...
... planning proton treatments makes it possible to precisely ... distributed inside the patient,s body, PALO ALTO, Calif., ... has received FDA 510(k) clearance for a new proton,scanning ... beams are used to target tumors and other abnormalities. ...
... Reliable, Quick Patient-Information Retrieval From Multiple ... Ill., Dec. 14 AT&T Inc. (NYSE: ... Associates, Ltd. (JOHA) has,awarded AT&T a three-year ... addition to other network solutions. Continuing its ...
... AMSTERDAM, December 14 Kiadis Pharma announced ... for regulatory,classification as a "cell based" medicinal product ... the European Medicines Agency (EMEA). Based upon,this regulatory ... a,next step Kiadis Pharma will file for orphan ...
... Online Help for Living Longer, ... Stronger, KIRKLAND, ... odds of needing long term care,increase. One solution is long term care insurance ... Financial Partners,(LTCFP), "is the insurance plus health habits to keep yourself on your ...
... generation begins to join the ranks of the retired so ... consumers, says a new study funded by the Economic and ... media creations, it seems that the caricatures of silver surfers ... of older people increasingly mirror those of the rest of ...
Cached Medicine News:Health News:NCI/ASCO host science writers' seminar 2Health News:Eclipse(TM) Proton Scanning Algorithm from Varian Medical Systems Receives FDA Clearance 2Health News:Eclipse(TM) Proton Scanning Algorithm from Varian Medical Systems Receives FDA Clearance 3Health News:Local Joliet Physician Group Selects AT&T for Managed Online Data Solutions 2Health News:Local Joliet Physician Group Selects AT&T for Managed Online Data Solutions 3Health News:ATIR Classified as "Cell Based" Medicinal Product by the EMEA 2Health News:As More Americans Live to 100, Long Term Care Insurance Leader Gives Health Assist 2Health News:Retirees spending freely 2
(Date:7/28/2014)... July 28, 2014  TNI BioTech, Inc. (OTCQB: ... focused on the development, marketing and distribution of ... definitive proxy materials with the Securities and Exchange ... of Shareholders to be held on Thursday, September ... The record date for determining those shareholders eligible ...
(Date:7/28/2014)... TOKYO , July 28, 2014 /PRNewswire/ ... appointed Roger Crystal , MD as Vice President ... the Global Business Development Product Acquisition & Licensing team ... in developing business strategy and partnerships in the precision ... to partner with biotechnology and pharmaceutical companies across the ...
(Date:7/28/2014)... -- PDL BioPharma, Inc. (PDL) (NASDAQ: PDLI ) ... 2014 financial results for the period ended June 30, 2014, ... will host a conference call and webcast that day at ... slide presentation relating to the call will be available via ... Call Details To access the live conference call via ...
Breaking Medicine Technology:TNI BioTech, Inc., Files Definitive Proxy Materials; Mails Letter Urging Shareholders to Vote the Proxy Card 2TNI BioTech, Inc., Files Definitive Proxy Materials; Mails Letter Urging Shareholders to Vote the Proxy Card 3ImaginAb Appoints Roger Crystal, MD as Vice President of Business Development 2PDL BioPharma to Announce Second Quarter 2014 Financial Results on August 11, 2014 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: