Navigation Links
Serum carcinoembryonic antigen level can reflect adrenal adenoma
Date:11/21/2007

The female patient, reported on the December 7 issue 45 of World J Gastroenterology, presented a rare case, with symptoms consistent with hyperadrenocorticism and hypercatecholaminism, and also had a Cushingoid appearance. The serum cortisol, dopamine and noradrenalin levels were elevated. Computed tomography detected a left adrenal mass measuring 3.5 cm -- 3.0 cm in diameter. Metaiodobenzylguanidine scintigraphy was negative. Unexpectedly, the serum carcinoembryonic antigen (CEA) level was elevated. Fluorodeoxyglucose positron emission tomography showed increased uptake in the adrenal tumor only, with a maximum standardized uptake value of 2.8. Selective venography and blood sampling revealed the concentrations of cortisol, catecholamines and carcinoembryonic antigen were significantly elevated in the drainage vein of the tumor. A diagnosis of carcinoembryonic antigen-producing benign adenoma was made. After preoperative management, Dr. Hori's group performed a combined lateral and anterior transperitoneal laparoscopic adrenectomy. The patient's vital signs remained stable during surgery. Histopathological examination revealed a benign adenoma. The cortisol, catecholamine and carcinoembryonic antigen levels normalized immediately after surgery.

Laparoscopic adrenectomy (LA) was first performed in 1992, and this safe and effective treatment is now used worldwide for the management of functioning and non-functioning adrenal tumors. The minimal skin incisions provide a sufficient surgical field, anastomosis and reconstruction are not required, hemostasis can be achieved using laparoscopic devices, and the resected tumor can be removed through the small skin incision. Many previous documents focused on LA have already described the advantages and shortcomings of the transperitoneal and retroperitoneal approaches. There are two transperitoneal approaches, lateral and anterior. Especially in left adrenal tumors and cases with more retroperitoneal fat, Hori et al. suggested that the combined lateral and anterior transperitoneal LA has the advantage of providing a sufficient surgical field and anatomical orientation in a timely manner, and that the combined approach allowed easy and early ligation of the drainage vein which was the source of the catecholamines.

When surgeons believe that the left adrenal tumor might be producing a large amount of CEA, Dr. Hori and colleagues recommend that investigators perform selective venography and direct blood sampling of the drainage vein of the tumor for verification, as this method was useful for detecting the source of CEA.


'/>"/>

Contact: You-De Chang
y.d.chang@wjgnet.com
0086-108-538-1892
World Journal of Gastroenterology
Source:Eurekalert

Related medicine news :

1. Nourishment Is Essential to a Youthful Appearance. Time to Feed Your Face with Serum_G
2. Data Show Vaprisol(R) Is Effective & Safe in Promptly Increasing Serum Sodium Levels in Patients With Euvolemic or Hypervolemic Hyponatremia
3. Panacea Pharmaceuticals Announces the Availability of CC Detect(SM), a Serum-Based Diagnostic Test for Colon Cancer
4. Planet Technologies Announces Agreement to Acquire Antigen Laboratories
5. Planet Technologies Announces Completion of Antigen Laboratories Acquisition
6. Adult offspring of parents with PTSD have lower cortisol levels
7. Study Demonstrates Marteks Algal DHA Oil Improves Blood Triglyceride Lipid Levels
8. Low level of neuronal receptor linked to mild cognitive impairment and Alzheimers disease
9. Cleveland-based Health Care Tech Company Within3 Names New CEO
10. LifeMasters Provides Tips for Maintaining a Healthy Blood Cholesterol Level
11. Cardiovascular Technologies to be Highlighted at 5th Annual Cleveland Clinic Medical Innovation Summit, Oct. 1-3
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... March 24, 2017 , ... In ... innovative EcoQube Frame vertical micro-veggies garden on Kickstarter . Surpassing the $100,000 ... – with nearly 2,000 consumers (and counting) already backing the campaign. , ...
(Date:3/24/2017)... ... March 24, 2017 , ... Viewers who like to ... critical historical facts, cultural practices, goods, services, and societal issues tend to appreciate and ... into the popular practice of utilizing running events for causes around the world. ...
(Date:3/24/2017)... , ... March 24, 2017 , ... “End Time GPS”: ... salient events will interrelate. “End Time GPS” is the creation of published author, ... expert while working on military munitions and space-vehicle projects. Now, at age ninety-one, he ...
(Date:3/23/2017)... CO (PRWEB) , ... March 23, 2017 , ... A ... bar for entry into teacher preparation programs. The NCTQ report suggests, based on a ... entry requirements would significantly improve teacher quality in the U.S. It argues that this ...
(Date:3/23/2017)... , ... March 23, 2017 , ... The IoT (Internet ... WiFi connectivity are making a huge impact on businesses and individual consumers alike. ... the IoT will have a value anywhere from $4 trillion to $11 trillion dollars ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... Mar 24, 2017 Research and Markets has ... Strategic Business Report" report to their offering. ... The report provides separate comprehensive analytics for the ... Europe , Asia-Pacific , Latin ... provided for the period 2015 through 2022. Also, a six-year historic analysis ...
(Date:3/24/2017)... -- HealthMine surveys with 9,250 insured consumers fielded from February ... want help from their plans in five key areas: ... 2) help closing gaps in care, 3) better digital ... relevant, real-time guidance. Meeting these needs is essential to ... A Reason to Stay Engaged in Health ...
(Date:3/24/2017)... and GENEVA , March 24, ... World Tuberculosis Day revitalizes efforts to develop sutezolid as ... On World Tuberculosis Day, TB Alliance and the Medicines ... clinical development of sutezolid, an antibiotic drug candidate which ... to the development of sutezolid in combination with other ...
Breaking Medicine Technology: