Seroquel's First- and Second-Line Patient Share Has Grown Since Last Year's Analysis of Prescribing Trends in Bipola...( Although Risperidone Is Now Available...),Health

Although Risperidone Is Now Available In Generics, There Is No Clear Evidence of Expanded Uptake in Early Lines of Therapy, According to a New Report from Decision Resources

Patient-Flow Forecasts Need to Take Into Account Shifts in Seroquel XR's Use by Line of Therapy Over the Next Two Years

WALTHAM, Mass., June 22 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that AstraZeneca Seroquel's first-line patient share grew two percent since last year's patient-level claims data analysis of prescribing trends in bipolar disorder. During this same time period other atypicals (with the exception of Pfizer's Geodon) lost first-line patient share which suggests that Seroquel's better penetration of first-line therapy came at the expense of others in the atypical class such as Bristol-Myers Squibb/Otsuka's Abilify and Eli Lilly's Zyprexa.

Although surveyed psychiatrists rate the overall attributes of Abilify higher than Seroquel/Seroquel XR, surveyed primary care physicians' assessment of these two agents is the opposite. Despite the advantage that surveyed psychiatrists give to Abilify over Seroquel on side-effect and safety attributes, Abilify's patient share is second to that of Seroquel in both first- and second-line therapy.

The new report entitled Treatment Algorithms in Bipolar Disorder also finds that although risperidone is now available in generics there is no clear evidence of its expanded uptake in early lines of therapy. Approximately 15 percent of surveyed physicians do not prescribe generic risperidone first-line and only one-third of surveyed physicians estimate that they prescribe generic risperidone first-line to more than half of their bipolar patients.

By pairing patient-level claims data with primary survey data, this report can be used to build pati
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