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Serious Mental Illness Tied to Higher Cancer, Injury Risk: Studies
Date:7/20/2012

FRIDAY, July 20 (HealthDay News) -- People with serious mental illnesses such as schizophrenia and bipolar disorder have a 2.6 times increased risk of developing cancer, a new study contends.

The findings raise questions about whether people with serious mental illness receive appropriate cancer screenings and preventive care to help them avoid cancer risk factors such as smoking, the researchers said.

"The increased risk is definitely there, but we're not entirely sure why," study leader Dr. Gail Daumit, an associate professor of medicine and psychiatry at the Johns Hopkins University School of Medicine, said in a Hopkins news release. "Are these people getting screened? Are they being treated? Something's going on."

The researchers analyzed data from more than 3,300 Maryland Medicaid beneficiaries with schizophrenia and bipolar disorder to determine how many of them were diagnosed with cancer between 1994 and 2004.

Compared to people in the general population, schizophrenia patients were more than 4.5 times more likely to develop lung cancer, 3.5 times more likely to develop colorectal cancer, and nearly three times more likely to develop breast cancer, the researchers found.

Patients with bipolar disorder had similarly increased risk for the three types of cancer, according to the study published in the July issue of the journal Psychiatric Services.

People with serious mental illness are more likely to smoke, which could explain their elevated risk for lung cancer, Daumit said.

She also noted that women with schizophrenia and bipolar disorder are less likely to have children and that childbearing is believed to reduce breast cancer risk. In addition, some drugs used to treat mental illness can increase levels of the hormone prolactin, a factor that has been linked to breast cancer.

The increased risk of colorectal cancer could be due to lifestyle issues such as smoking, lack of e
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