Navigation Links
Sepsis Plus Heart Rhythm Disorder Linked to Stroke, Death
Date:11/13/2011

SUNDAY, Nov. 13 (HealthDay News) -- Patients who develop atrial fibrillation -- a heart rhythm disorder -- for the first time while they are hospitalized with severe sepsis are at increased risk for stroke and death, a new study finds.

Atrial fibrillation (AF) is one of the most common heart rhythm problems among critically ill patients, according to background study information. Six percent to 20 percent of patients with severe sepsis develop new-onset atrial fibrillation, which suggests that severe sepsis may contribute to the condition, the researchers wrote.

Their analysis of 2007 data from California hospitals showed that patients with severe sepsis accounted for 14 percent of all new-onset atrial fibrillation that occurred in hospitalized patients. The researchers also found that patients with severe sepsis were nearly seven times more likely to develop new-onset AF than those without severe sepsis.

Factors associated with increased risk of new-onset atrial fibrillation in patients with severe sepsis included; being older, white and male; a history of heart failure, obesity, cancer and stroke; and organ failures, respiratory failure and renal failure.

Developing the faulty heart rhythm increased the risk of ischemic stroke (reduced blood flow to the brain) and death among patients hospitalized with severe sepsis. In-hospital ischemic stroke occurred in 75 of 2,896 (2.6 percent) with new-onset atrial fibrillation, compared with 57 of 9,986 (0.57 percent) with preexisting AF and 249 of 36,200 (0.69 percent) without AF.

In-hospital death occurred in 56 percent (1,629) of severe sepsis patients with new-onset atrial fibrillation and 39 percent (18, 027) of those without it.

The researchers said a number of factors might explain the increased stroke risk in this group of patients with severe sepsis.

"Severe sepsis alone may be associated with an increased risk of stroke through hemodynamic [blood circulation] collapse, increased systemic inflammation, and coagulopathy [clotting/bleeding disorder]. New-onset AF may simply be a marker for greater severity of illness and, thus, greater stroke risk," wrote Dr. Allan J. Walkey, of the Boston University School of Medicine, and colleagues.

The study appears online Nov. 13 in the Journal of the American Medical Association and will be presented at the American Heart Association annual meeting in Orlando, Fla.

"Given projected estimates of severe sepsis incidence in 1 million Americans in 2011, it is likely that new-onset AF occurs in more than 60,000 patients with severe sepsis in the United States each year," the researchers wrote.

"Current guidelines do not address AF that occurs in the setting of severe sepsis or acute infection, suggesting that new-onset AF that occurs during severe sepsis is an underrecognized public health problem. If our findings of increased stroke and death in the setting of AF and severe sepsis are replicated in other data sets, then it will be important to examine management strategies that might diminish the risk of adverse outcomes associated with AF during severe sepsis."

More information

The U.S. National Heart, Lung, and Blood Institute has more about atrial fibrillation.

-- Robert Preidt

SOURCE: Journal of the American Medical Association, news release, Nov. 10, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Hospital-Acquired Sepsis, Pneumonia a Growing Menace
2. Two Sepsis Treatments Look Equally Effective
3. Fast sepsis test can save lives
4. The death switch in sepsis also promotes survival
5. Gene protects lung from damage due to pneumonia, sepsis, trauma, transplants
6. Hospital Spending Doesnt Affect Sepsis Survival Rates
7. Roundworm could provide new treatment for sepsis
8. Streptococci and E. coli continue to put newborns at risk for sepsis
9. Study: Resiniferatoxin may increase sepsis-related mortality
10. Quicker detection and treatment of severe sepsis
11. U.S. Stroke Belt May Also Be Sepsis Belt
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Sepsis Plus Heart Rhythm Disorder Linked to Stroke, Death
(Date:6/20/2017)... ... June 20, 2017 , ... Hayes, Inc., a ... new eBook titled “ 5 Questions to Ask Before Entering the Maze of ... Genetic Test Evaluation (GTE) team, the book explores the various types of the ...
(Date:6/20/2017)... ... June 20, 2017 , ... EdChoice and ... of school choice can promote economic development in economically distressed urban areas. The ... to the report, contributed to the economic development of the city of Santa ...
(Date:6/20/2017)... ... 20, 2017 , ... MindTouch , the leading provider ... to announce Touchpoints integrations. MindTouch Touchpoints easily integrate product documentation with ... provide a seamless customer experience. , Truly “plug and play,” Touchpoints are easily ...
(Date:6/20/2017)... (PRWEB) , ... June 20, 2017 , ... As a ... on the link between stroke and gum disease. Those with bleeding gums in Vancouver, ... left untreated, this condition can lead to heart disease, stroke and diabetes. Drs. Parviz ...
(Date:6/20/2017)... ... 20, 2017 , ... This year, participants in the Institute ... product improvements that could reduce the occurrence of unplanned extubations (UEs). , ... or to provide medication. Sometimes, patient movement can cause unplanned extubations which is ...
Breaking Medicine News(10 mins):
(Date:6/14/2017)...  In 2016, Embodied Labs took top ... and came away with $25,000 in seed-fund investment. Embodied ... as "entering the life of another" and by the ... to medical professionals in an entirely new dimension." Building ... finalist for the Department of Education,s EdSimChallenge, where they ...
(Date:6/12/2017)... -- Kineta, Inc., a biotechnology company focused on the development ... of R&D and Head of Virology Kristin Bedard has been ... Northwest and Beyond meeting sponsored by Life Science Washington. ... 8:30-10:30 AM PDT at the Agora Conference Center in ... will be joined by other leaders in infectious disease research ...
(Date:6/10/2017)... Ala. , June 9, 2017  Shane K. Burchfield, DPM, ... recognized for excellence as a Podiatrist in Alabama ... Podiatry at Family First Foot Care. He brings over 20 years ... medicine, pain management and healthcare, to his role. ... First Foot Care, PC is pleased to welcome you ...
Breaking Medicine Technology: