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Sensor necklace aims to increase elderly and clinical trial participant drug compliance
Date:3/5/2008

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According to a 2005 Wall Street Journal Online/Harris Interactive Health Care Poll, one in three U.S. adults who had been prescribed drugs to take on a regular basis reported that they did not follow the doctor-recommended course of treatment, with two-thirds reporting that they simply forgot to take their medication.

This technology can also help researchers and pharmaceutical companies conduct more accurate clinical trials of new drugs. Currently, compliance is determined by medication diaries kept by the patients, but patients are prone to fill out diaries just before meetings held to monitor their progress and they may adjust their medication to compensate for missed doses.

Inaccurate data from clinical trials can affect decisions made about new drugs, potentially impacting millions of people.

If each drug trial volunteer had to wear a MagneTrace necklace, the exact date, time and dose would be recorded, rather than relying on the patients memory and honesty, said Ghovanloo.

This technology also has the potential to reduce the size of clinical trials and reduce the need to repeat them. This alone can reduce drug company expenditures, in turn reducing the cost of new drugs for consumers. MagneTrace is suitable for small- and large-scale clinical trials, as well as individual patients, according to Ghovanloo.

A patient cannot cheat the system by passing the pill past the necklace sensors on the outside of the neck because the signal processing algorithm is smart enough to only look for the pills magnetic signature while it passes through the esophagus, said Ghovanloo, who started working on this project about two years ago at N.C. State University.

The researchers have designed and tested an artificial neck, built from a PVC pipe filled with plastic straws. They place a necklace containing an array of sensitive magneto-inductive sensors around the artificial neck to study detection of a p
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Contact: Abby Vogel
avogel@gatech.edu
404-385-3364
Georgia Institute of Technology Research News
Source:Eurekalert  

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