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Senetek PLC Announces Key Personnel Appointments
Date:6/9/2008

oducts and were responsible for the acquisition and development of the Obagi highly successful Vitamin C product line.

Phillip Rose commented on the clinical data supporting Pyratine-6(TM), stating that "Pyratine-6(TM) has demonstrated a high degree of clinical efficacy in treating subjects with photodamaged skin and proved most beneficial in patients with acne rosacea. He went on to note that Pyratine-6(TM) worked faster than Kinerase and in a comparative analysis completed by the investigators of both Kinerase and Pyratine-6(TM), Pyratine-6(TM) showed superiority in the reduction of fine lines and wrinkles, improving skin texture and reducing mottled hyperpigmentation."

Mr. Bruner stated he was "most pleased to be associated with Senetek and to have the opportunity to help launch a superior product such as Pyratine- 6(TM), working along side Phil Rose. Pyratine-6(TM) has multiple differential advantages over the competition, not to mention its positive effects on skin cells, its antioxidant properties and its ability to increase the moisture content in skin, which is essential for healthy skin."

"Phillip and David are great additions to the Senetek team, having had great successes in the physician market, launching new products. They bring with them a thorough understanding of the market along with key relationships with influential physicians and thought leaders," commented Frank Massino, Chairman & Chief Executive Officer of Senetek.

About Senetek PLC

Senetek PLC (OTC Bulletin Board: SNKTY) is a Life Sciences company engaged in the development of breakthrough technologies that target the science of healthy aging. The Company's extensive research collaborations have resulted in a strong pipeline of patented compounds and products with broad therapeutic applications and a leading presence in dermatology. Senetek collaborates with established specialty pharmaceutical companies in the final development and marketing of its propriet
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