Navigation Links
Selenium, Vitamins E and C Won't Prevent Prostate Cancer
Date:12/9/2008

Large trials fail to confirm suspected benefit,,,,

TUESDAY, Dec. 9 (HealthDay News) -- Selenium, vitamin E and vitamin C won't prevent men from getting prostate cancer.

In findings that were released early because of the public health implications, the results of two large randomized, controlled clinical trials showed the supplements failed to provide a cancer-prevention benefit, despite past findings that seemed to indicate great promise -- particularly for selenium. Both studies were expected to be published in the Jan. 7 print issue of the Journal of the American Medical Association.

"Our results showed no evidence of benefit from selenium and vitamin E on prostate cancer and other cancers," said the lead author of one of the studies, Dr. Scott Lippman, a professor of medicine in the division of cancer medicine at M.D. Anderson Cancer Center, in Houston.

Lippman's study, known as the SELECT trial, included more than 35,000 men. Black men included in the study were all over 50, and men from other races were all over 55. (Blacks have a higher risk of developing prostate cancer than do men of other races, according to the American Cancer Society.)

The men were randomly assigned to one of four groups: selenium; vitamin E; selenium and vitamin E; or a placebo. The average follow-up time was more than five years.

The researchers found no statistically significant difference between the groups, and the trial was ended early, because there was no convincing evidence of efficacy.

The second study, done by Harvard researchers, included almost 15,000 male physicians over 50 who were randomly assigned to receive vitamin E, vitamin C, or a placebo. The average follow-up time for this trial was eight years.

Again, no statistically significant benefits were found from either vitamin C or E when it came to preventing prostate and other cancers.

These studies are just the latest in a long list of recent research that's been discounting the use of individual vitamins and supplements for chemoprevention. Other recent studies have suggested that vitamins, B, C, D, E, folic acid and calcium taken alone, or in various combinations, aren't effective for cancer prevention.

"Single-agent interventions, even in combinations, may be an ineffective approach to primary prevention in average-risk populations," wrote Dr. Peter Gann, the author of an accompanying editorial in the same issue of the journal.

Andrew Shao, vice president of scientific and regulatory affairs for the Center for Responsible Nutrition in Washington, D.C., said he thought researchers need to "redefine our expectations for nutrients. They're not magic bullets, though they do have tangible effects."

Shao said studies that look at vitamins and cancer prevention tend to treat vitamins the same way they would a targeted pharmaceutical agent. But, he said, "the whole body is affected by nutrients, while pharmaceuticals are highly specialized and targeted to specific cells."

"It would be a mistake to look at one trial that answers a very specific question and say these nutrients don't work at all," said Shao.

Lippman, however, said he doesn't recommend the use of supplements for cancer prevention. "There's no evidence to support taking these," he said.

More information

To learn more about prostate cancer prevention, visit the American Cancer Society.



SOURCES: Scott Lippman, M.D., professor, medicine, division of cancer medicine, M.D. Anderson Cancer Center, Houston; Andrew Shao, Ph.D., vice president, scientific and regulatory affairs, Center for Responsible Nutrition, Washington D.C.; Jan. 7, 2009, Journal of the American Medical Association


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study finds selenium, vitamin E do not prevent prostate cancer
2. Changing Times Vitamins to Sponsor Emmanuel Manny Pacquiao in Upcoming Fight With Oscar De La Hoya.
3. ClutchWave LLC Launches PricePlow.com: Price Shopping For Supplements and Vitamins
4. King Features Syndicate and Changing Times Vitamins Sign Licensing Agreement for Popeye(R) the Sailor Man in the Water Drink Category.
5. Two Antioxidant Vitamins Dont Protect Against Heart Disease
6. Can Vitamins and Minerals Prevent Hearing Loss?
7. Can vitamins and minerals prevent hearing loss?
8. Vitamins E and C supplements not effective for prevention of cardiovascular disease in men
9. Folic acid, B vitamins do not appear to affect cancer risk
10. Folic Acid and Other B Vitamins Wont Help Prevent Cancer
11. Meijer Pharmacies to Offer Free Pre-Natal Vitamins
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Selenium, Vitamins E and C Won't Prevent Prostate Cancer
(Date:7/26/2017)... ... 2017 , ... The number of adults 65 years or older is expected ... asthma control in the population are not well described. In a study published in ... journal of the American Academy of Allergy, Asthma & Immunology (AAAAI), researchers identified factors ...
(Date:7/25/2017)... ... July 25, 2017 , ... ... department joining as Regional Account Manager for the Northeast and Florida regions. In ... liquidation of their obsolete medical assets. , Jennifer joins Centurion with a wealth ...
(Date:7/25/2017)... ... July 25, 2017 , ... Therachat , ... be exhibiting and providing demos of its smart journaling platform at the 125th ... in Washington D.C. from August 3-6, 2017. , The APA Annual Convention is ...
(Date:7/25/2017)... ... July 25, 2017 , ... Dr. Gina Negrette, a skilled ... than a decade of experience in psychiatry, treating clients in diverse settings, including ... disorders, psychotic and manic conditions, as well as those who were fighting simply ...
(Date:7/25/2017)... Austin, TX (PRWEB) , ... July 25, 2017 , ... ... medical emergencies in the Austin, TX area 24 Hours a day. , The ... in Austin, TX. , “We’ve been open four months now and things are ...
Breaking Medicine News(10 mins):
(Date:7/24/2017)... -- Diplomat Pharmacy, Inc. (NYSE: DPLO ) announced ... operating results on Monday, August 7, 2017 after market ... p.m. ET. Shareholders ... of the conference call by dialing 877-201-0168 or 647-788-4901 ... 15 minutes prior to the call. A live webcast ...
(Date:7/20/2017)... 20, 2017  Prime Therapeutics LLC (Prime) released this statement ... following today,s Institute for Clinical and Economic Review,s (ICER) ... effectiveness and value of abuse-deterrent formulations (ADF) of opioids. Prime ... at the meeting. ... benefit to the use of abuse-deterrent formulations (ADF) in opioids ...
(Date:7/14/2017)... , July 13, 2017 It should come ... States is in the midst of a crippling ... , since 1999, the number of overdose deaths from opiate-based ... in over half a million dead from 2001 to 2015". ... oxycodone, and hydrocodone has similarly quadrupled, drawing a compelling link ...
Breaking Medicine Technology: