Navigation Links
Seizure Meds Can Be Safely Withdrawn From Kids With Epilepsy
Date:12/8/2008

Study finds relatively low risk of developing intractable disease

MONDAY, Dec. 8 (HealthDay News) -- It's generally safe to stop giving anti-seizure medication to children with epilepsy who've achieved seizure-freedom while on the medication, because these children aren't at high risk of later developing intractable epilepsy, a Mayo Clinic study finds.

Intractable epilepsy, which affects about 10 percent of children with epilepsy, is a condition in which medications alone don't control seizures and in which seizures have a disabling effect on the patient's quality of life.

"It is often recommended that children with epilepsy who become seizure-free on anti-seizure medications be withdrawn from the drugs to avoid side effects of long-term use. Those potential side effects include cognitive slowing, incoordination, weight change, behavioral decline, and liver damage," pediatric neurologist Dr. Katherine Nickels said in a Mayo news release. "However, few previous studies had examined the risk of intractable epilepsy following withdrawal of anti-seizure medication, and the reported risks varied widely."

In this study, Nickels and colleagues reviewed the records of 152 children, ages 1 month to 16 years, who were diagnosed with new-onset epilepsy between 1990 and 2000 and treated with anti-seizure medication. Of those children, 56 (37) percent achieved seizure-freedom and were taken off their medication.

After an average follow-up of eight years, 20 of the 56 children experienced at least one seizure recurrence. Fifteen of those 20 children re-started treatment with anti-seizure medication. Eight of those 15 achieved seizure-freedom within one year, two achieved seizure-freedom after two years, and three developed intractable epilepsy. Overall, intractable epilepsy developed in 5 percent of the 56 children who were taken off anti-seizure medication following seizure-freedom, the study found.

"The risk of children developing intractable epilepsy after withdrawal of anti-seizure medication was only five percent, which is similar to the risk of intractable epilepsy at the time of initial diagnosis of epilepsy in children," Nickels said. "Therefore, the children who achieve seizure-freedom on anti-seizure medication should be considered for withdrawal without high risk of intractable epilepsy."

The study was to be presented Dec. 7 in Seattle at the annual meeting of the American Epilepsy Society.

More information

The Epilepsy Foundation has more about epilepsy.



-- Robert Preidt



SOURCE: Mayo Clinic, news release, Dec. 7, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Mayo Clinic finds it generally safe to withdraw anti-seizure medication in children with epilepsy
2. New target discovered to treat epileptic seizures following brain trauma or stroke
3. Clue to Cause of Epileptic Seizures Discovered
4. LegalView Informs Chantix Patients of Risk of Seizures Leading to Traffic Accidents
5. Keppra XR(TM) Offers Convenient Dosing For People With Partial Onset Seizures
6. NIAID media availability: Seizures following parasitic infection associated with brain swelling
7. Sedative Could Be Deadly in People With Seizures
8. Antiseizure Drug Could be Fatal
9. Anti-seizure drug could be fatal
10. Seizures in newborns can be detected with small, portable brain activity monitors
11. Failure to Take Seizure Drugs Boosts Death Risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Seizure Meds Can Be Safely Withdrawn From Kids With Epilepsy
(Date:6/26/2016)... ... , ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect ... a whole new perspective by using the title layers in ProSlice Levels to ... ProSlice Levels contains over 30 Different presets to choose from. FCPX users ...
(Date:6/25/2016)... D.C. (PRWEB) , ... June 25, 2016 , ... ... discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, ... their work on several important health care topics including advance care planning, healthcare ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the ... Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , “We ... new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice ...
(Date:6/25/2016)... Montreal, Canada (PRWEB) , ... June 25, 2016 , ... ... the pursuit of success. In terms of the latter, setting the bar too high ... low, risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Any dentist who has made ... the current process. Many of them do not even offer ... difficulties and high laboratory costs involved. And those who ARE ... at such a high cost that the majority of today,s ... Dr. Parsa Zadeh , founder of Dental Evolutions Inc. ...
(Date:6/23/2016)... Research and Markets has announced the addition of the ... to 2022" report to their offering. ... financial data derived from varied research sources to present unique ... on the market during the next five years, including a ... markets, regional and country level analysis. The report provides a ...
(Date:6/23/2016)... MOUNTAIN VIEW, Calif. , June 23, 2016 ... 9:00 a.m. CST on Thursday, July 7, 2016 , , ... kayla.belcher@frost.com ) , , , , EXPERT PANELISTS:  ... Sciences, Nitin Naik; Senior Industry Analyst, Christi Bird; Senior Industry Analyst, ... The global pharmaceutical industry is witnessing ...
Breaking Medicine Technology: