Navigation Links
Seizure Meds Can Be Safely Withdrawn From Kids With Epilepsy
Date:12/8/2008

Study finds relatively low risk of developing intractable disease

MONDAY, Dec. 8 (HealthDay News) -- It's generally safe to stop giving anti-seizure medication to children with epilepsy who've achieved seizure-freedom while on the medication, because these children aren't at high risk of later developing intractable epilepsy, a Mayo Clinic study finds.

Intractable epilepsy, which affects about 10 percent of children with epilepsy, is a condition in which medications alone don't control seizures and in which seizures have a disabling effect on the patient's quality of life.

"It is often recommended that children with epilepsy who become seizure-free on anti-seizure medications be withdrawn from the drugs to avoid side effects of long-term use. Those potential side effects include cognitive slowing, incoordination, weight change, behavioral decline, and liver damage," pediatric neurologist Dr. Katherine Nickels said in a Mayo news release. "However, few previous studies had examined the risk of intractable epilepsy following withdrawal of anti-seizure medication, and the reported risks varied widely."

In this study, Nickels and colleagues reviewed the records of 152 children, ages 1 month to 16 years, who were diagnosed with new-onset epilepsy between 1990 and 2000 and treated with anti-seizure medication. Of those children, 56 (37) percent achieved seizure-freedom and were taken off their medication.

After an average follow-up of eight years, 20 of the 56 children experienced at least one seizure recurrence. Fifteen of those 20 children re-started treatment with anti-seizure medication. Eight of those 15 achieved seizure-freedom within one year, two achieved seizure-freedom after two years, and three developed intractable epilepsy. Overall, intractable epilepsy developed in 5 percent of the 56 children who were taken off anti-seizure medication following seizure-freedom, the study found.

"The risk of children developing intractable epilepsy after withdrawal of anti-seizure medication was only five percent, which is similar to the risk of intractable epilepsy at the time of initial diagnosis of epilepsy in children," Nickels said. "Therefore, the children who achieve seizure-freedom on anti-seizure medication should be considered for withdrawal without high risk of intractable epilepsy."

The study was to be presented Dec. 7 in Seattle at the annual meeting of the American Epilepsy Society.

More information

The Epilepsy Foundation has more about epilepsy.



-- Robert Preidt



SOURCE: Mayo Clinic, news release, Dec. 7, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Mayo Clinic finds it generally safe to withdraw anti-seizure medication in children with epilepsy
2. New target discovered to treat epileptic seizures following brain trauma or stroke
3. Clue to Cause of Epileptic Seizures Discovered
4. LegalView Informs Chantix Patients of Risk of Seizures Leading to Traffic Accidents
5. Keppra XR(TM) Offers Convenient Dosing For People With Partial Onset Seizures
6. NIAID media availability: Seizures following parasitic infection associated with brain swelling
7. Sedative Could Be Deadly in People With Seizures
8. Antiseizure Drug Could be Fatal
9. Anti-seizure drug could be fatal
10. Seizures in newborns can be detected with small, portable brain activity monitors
11. Failure to Take Seizure Drugs Boosts Death Risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Seizure Meds Can Be Safely Withdrawn From Kids With Epilepsy
(Date:2/10/2016)... AZ (PRWEB) , ... February 10, 2016 , ... Ongoing ... the Aging Life Care Association™ (ALCA) to conduct a survey that takes a closer ... experts released today illustrates the prevalence and causes of TBI among the aging population, ...
(Date:2/10/2016)... (PRWEB) , ... February 10, 2016 , ... AxoGen, Inc. ... will report results for the fourth quarter and full year ended December 31, 2015 ... a conference call and webcast for the investment community following the release at 4:30 ...
(Date:2/10/2016)... ... ... For additional information contact Phyllis Strupp 480-488-5858 , Brain improves with age, ... Guide to Brain Training" by award-winning author Phyllis Strupp explains how brain ... 16, 2016. A free review copy is available to the media at NetGalley ...
(Date:2/10/2016)... ... February 10, 2016 , ... IDEX Health & Science, LLC ... steel (PLS) columns combine the strength of traditional stainless steel with the chemical ... samples while operating at ultra-high pressures of 20,000 psi. The higher operating pressures ...
(Date:2/10/2016)... , ... February 10, 2016 , ... The recreational use ... enthusiasts in the state still face a lot of restrictions as to where they ... intended for private, personal use” and that cannabis “may not be consumed openly or ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... --> --> ... Packaging Equipment Market by Package Type (Blister, Strip, Bottle, ... Type (Tablet, Powder, Cream, Syrup, Aseptic Liquid, Aerosol) - ... market during the forecast period of 2015 to 2020. ... of 6.9% during the forecast period to reach USD ...
(Date:2/10/2016)... 10, 2016 The campaign aims to ... 5 years reach the milestone of their 5 th birthday ... ensure 2,50,532 children between the ages of 2 - 5 years ... --> The campaign aims to ensure ... reach the milestone of their 5 th birthday   ...
(Date:2/9/2016)... , Feb. 9, 2016  Insulet Corporation (NASDAQ: PODD ... insulin pump technology with its OmniPod ® ... Lemoine has been appointed to Insulet,s Board of Directors. ... directors, eight of whom are independent. --> ... of audit and finance experience and a deep knowledge of ...
Breaking Medicine Technology: