Navigation Links
Sedentary Lifestyle Accelerates Aging
Date:1/28/2008

Active people biologically younger than couch potato set, British study suggests

MONDAY, Jan. 28 (HealthDay News) -- People who are physically active in their free time may be biologically younger than couch potatoes, a new British study suggests.

"A sedentary lifestyle increases the propensity to aging-related diseases and premature death. Inactivity may diminish life expectancy not only by predisposing to aging-related diseases, but also because it may influence the aging process itself," study author Lynn F. Cherkas, of King's College London, said in a prepared statement.

The researchers looked at the physical activity levels, smoking habits and socioeconomic status of 2,401 white twins. The researchers also collected DNA samples from participants, and examined the length of telomeres-repeated sequences at the end of chromosomes in white blood cells (leukocytes). Leukocyte telomeres shorten over time and may serve as a marker of a person's biological age.

Overall, the study participants had an average telomere loss of 21 nucleotides (structural units) per year. But those who were more active in their leisure time had longer leukocyte telomeres than those who were less active.

"Such a relationship between leukocyte telomere length and physical activity remained significant after adjustment for body-mass index, smoking, socioeconomic status and physical activity at work," the authors wrote.

"The mean difference in leukocyte telomere length between the most active [who performed an average of 199 minutes of physical activity per week] and least active [16 minutes of physical activity per week] subjects was 200 nucleotides, which means that the most active subjects had telomeres the same length as sedentary individuals up to 10 years younger, on average."

Oxidative stress damage caused to cells by exposure to oxygen and inflammation may be a factor contributing to shorter telomere length in sedentary people. Stress has also been linked to telomere length. Exercise may reduce stress and its effect on telomeres and the aging process, the study authors suggested.

"The U.S. guidelines recommend that 30 minutes of moderate-intensity physical activity at least five days a week can have significant health benefits," they wrote. "Our results underscore the vital importance of these guidelines. They show that adults who partake in regular physical activity are biologically younger than sedentary individuals. This conclusion provides a powerful message that could be used by clinicians to promote the potential anti-aging effect of regular exercise."

But more research is needed to confirm a direct link between physical activity and aging, the study added.

"Persons who exercise are different from sedentary persons in many ways, and although certain variables were adjusted for in this analysis, many additional factors could be responsible for the biological differences between active and sedentary persons, a situation referred to by epidemiologists as residual confounding," Dr. Jack M. Guralnik, of the U.S. National Institute on Aging, wrote in an accompanying editorial.

"Nevertheless, this article serves as one of many pieces of evidence that telomere length might be targeted in studying aging outcomes," he added.

The study was published in the Jan. 28 issue of the Archives of Internal Medicine.

More information

The U.S. Centers for Disease Control and Prevention has more about physical activity.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, Jan. 28, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Small Lifestyle Changes Can Boost Longevity
2. Gaiam Inc., The Leader in Innovative Lifestyle Solutions, Announces New DVD Series Created with Mayo Clinic
3. For Healthier Lifestyles That Can Be Habit-Forming, Take the Meals Matter Nutrition & Fitness Challenge!
4. New Poll Announces Link Between Friends and Family Influence and a Healthy Lifestyle
5. Discovery Healths Fifth Annual National Body Challenge Takes a Stand Against Obesity by Offering the Keys to Adopting a Healthy, Active Lifestyle
6. Employees with workplace flexibility have healthier lifestyle habits
7. Lifestyle and cancer prevention: Making choices that change cancer risk
8. Cascade Fresh Yogurt Announces Two Products to Optimize a Healthy Lifestyle
9. it Girl Public Relations Adds O.N.I. New Organic Food Delivery Service to Its Lifestyle Division
10. Older Hypertension Patients Less Likely to Get Lifestyle Advice
11. Demystifying Diabetes: The Complete Diabetes Lifestyle
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Sedentary Lifestyle Accelerates Aging
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... established the certification process to promote standards of excellence for the field of ... scheduled for March 22 – 25, 2018 in Orlando, Florida at the Omni ...
(Date:10/13/2017)... ... 2017 , ... Lori R. Somekh, founder of the Law Office of ... elder law and special needs planning attorneys. “Membership in ElderCounsel helps our office remain ... to network with elder law attorneys nationwide,” said Somekh. , ElderCounsel ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) of ... collection of specialty vendors and unique items from across the nation, this holiday-themed event ... wellness services offered by the VNA. The boutique will be open Saturday, November ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House ... most popular and least understood books in the Holy Scriptures, Revelation. The Book of ... baffled scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl ...
(Date:10/13/2017)... ... ... Journey: From the Mountains to the Mission Field”: the story of a missionary couple ... From the Mountains to the Mission Field” is the creation of published author, Carole ... and currently teaches a class of ladies at her church, which she has taught ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... , Oct. 10, 2017   West Pharmaceutical ... innovative solutions for injectable drug administration, today shared the ... ID Adapter for improving the intradermal administration of polio ... Skin Vaccination Summit in May 2017 by Dr. ... Polio Department, World Health Organization (WHO), and recently published ...
(Date:10/4/2017)... 4, 2017 OBP Medical , ... medical devices, today announced regulatory approval from ... (or Agência Nacional de Vigilância Sanitária (ANVISA)) to ... surgical retractor with integrated LED light source and ... and exposure of a tissue pocket or cavity ...
(Date:10/2/2017)... Denmark , Oct. 2, 2017 The Rebound ... in the struggle to reverse the tide of prescription drug ... for regulating their medicine intake and stepping down their dosage ... set to launch in December 2017; the first 100,000 people ... Learn more at http://www.rebound-solution.com/ ...
Breaking Medicine Technology: