Navigation Links
Sedentary Lifestyle Accelerates Aging
Date:1/28/2008

Active people biologically younger than couch potato set, British study suggests

MONDAY, Jan. 28 (HealthDay News) -- People who are physically active in their free time may be biologically younger than couch potatoes, a new British study suggests.

"A sedentary lifestyle increases the propensity to aging-related diseases and premature death. Inactivity may diminish life expectancy not only by predisposing to aging-related diseases, but also because it may influence the aging process itself," study author Lynn F. Cherkas, of King's College London, said in a prepared statement.

The researchers looked at the physical activity levels, smoking habits and socioeconomic status of 2,401 white twins. The researchers also collected DNA samples from participants, and examined the length of telomeres-repeated sequences at the end of chromosomes in white blood cells (leukocytes). Leukocyte telomeres shorten over time and may serve as a marker of a person's biological age.

Overall, the study participants had an average telomere loss of 21 nucleotides (structural units) per year. But those who were more active in their leisure time had longer leukocyte telomeres than those who were less active.

"Such a relationship between leukocyte telomere length and physical activity remained significant after adjustment for body-mass index, smoking, socioeconomic status and physical activity at work," the authors wrote.

"The mean difference in leukocyte telomere length between the most active [who performed an average of 199 minutes of physical activity per week] and least active [16 minutes of physical activity per week] subjects was 200 nucleotides, which means that the most active subjects had telomeres the same length as sedentary individuals up to 10 years younger, on average."

Oxidative stress damage caused to cells by exposure to oxygen and inflammation may be a factor contributing to shorter telomere length in sedentary people. Stress has also been linked to telomere length. Exercise may reduce stress and its effect on telomeres and the aging process, the study authors suggested.

"The U.S. guidelines recommend that 30 minutes of moderate-intensity physical activity at least five days a week can have significant health benefits," they wrote. "Our results underscore the vital importance of these guidelines. They show that adults who partake in regular physical activity are biologically younger than sedentary individuals. This conclusion provides a powerful message that could be used by clinicians to promote the potential anti-aging effect of regular exercise."

But more research is needed to confirm a direct link between physical activity and aging, the study added.

"Persons who exercise are different from sedentary persons in many ways, and although certain variables were adjusted for in this analysis, many additional factors could be responsible for the biological differences between active and sedentary persons, a situation referred to by epidemiologists as residual confounding," Dr. Jack M. Guralnik, of the U.S. National Institute on Aging, wrote in an accompanying editorial.

"Nevertheless, this article serves as one of many pieces of evidence that telomere length might be targeted in studying aging outcomes," he added.

The study was published in the Jan. 28 issue of the Archives of Internal Medicine.

More information

The U.S. Centers for Disease Control and Prevention has more about physical activity.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, Jan. 28, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Small Lifestyle Changes Can Boost Longevity
2. Gaiam Inc., The Leader in Innovative Lifestyle Solutions, Announces New DVD Series Created with Mayo Clinic
3. For Healthier Lifestyles That Can Be Habit-Forming, Take the Meals Matter Nutrition & Fitness Challenge!
4. New Poll Announces Link Between Friends and Family Influence and a Healthy Lifestyle
5. Discovery Healths Fifth Annual National Body Challenge Takes a Stand Against Obesity by Offering the Keys to Adopting a Healthy, Active Lifestyle
6. Employees with workplace flexibility have healthier lifestyle habits
7. Lifestyle and cancer prevention: Making choices that change cancer risk
8. Cascade Fresh Yogurt Announces Two Products to Optimize a Healthy Lifestyle
9. it Girl Public Relations Adds O.N.I. New Organic Food Delivery Service to Its Lifestyle Division
10. Older Hypertension Patients Less Likely to Get Lifestyle Advice
11. Demystifying Diabetes: The Complete Diabetes Lifestyle
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Sedentary Lifestyle Accelerates Aging
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, an ... Dr. Cheng has extensive experience with all areas of orthodontics, including robotic Suresmile ... orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can ...
(Date:6/24/2016)... ... 24, 2016 , ... The Haute Beauty Network, affiliated with ... as a prominent plastic surgeon and the network’s newest partner. , Dr. ... handsome men, look naturally attractive. Plastic surgery should be invisible.” He stands by ...
(Date:6/24/2016)... MD (PRWEB) , ... June 24, 2016 , ... ... protocols for human induced pluripotent stem (iPS) cells and other difficult to transfect ... G9™ Cloning Medium. The PluriQ™ G9™ Gene Editing System is a ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... ANGELES , June 23, 2016 ... CAPR ), a biotechnology company focused ... therapeutics, today announced that patient enrollment in its ... in Duchenne) has exceeded 50% of its 24-patient ... enrollment in the third quarter of 2016, and ...
(Date:6/23/2016)... and INDIANAPOLIS , June ... receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is any ... scholarship winners, announced today online at www.diabetesscholars.org ... type 1 diabetes stand in the way of academic ... supported the Foundation,s scholarship program since 2012, and continues ...
(Date:6/23/2016)... , June 23, 2016 The vast majority ... outpatient dialysis facility.  Treatments are usually 3 times a ... per visit, including travel time, equipment preparation and wait ... but especially grueling for patients who are elderly and ... skilled nursing and rehabilitation centers for some duration of ...
Breaking Medicine Technology: