Navigation Links
Sedative Could Be Deadly in People With Seizures
Date:10/28/2008

At high doses, propofol tied to cardiac arrest in patients with a form of epilepsy

TUESDAY, Oct. 28 (HealthDay News) -- Use of the sedative propofol is associated with a high risk for complications and even death in patients with prolonged seizures, according to a study by researchers at the Mayo Clinic in Rochester, Minn.

The study included 39 patients with refractory status epilepticus (RSE) -- prolonged seizures that don't respond to initial treatment. The condition occurs in patients with primary epilepsy and in those with other conditions such as trauma, tumors and infections that affect the brain.

Propofol is used to treat patients with RSE, but is more commonly used for sedation during surgery or other patient procedures. In those situations, propofol is used at a much lower dose and shorter duration than when it's used to treat RSE, according to background information in an American College of Chest Physicians news release on the Mayo study.

"Patients with RSE treated with propofol are at high risk for propofol-related side effects because of the high propofol infusion rates and prolonged treatment duration necessary in these patients. However, it is well described that propofol toxicity can occur even with brief exposure to the drug," study author Dr. Vivek Iyer, of the Mayo Clinic, said in the news release.

In the study, 39 patients (average age 54) were admitted to the intensive care unit with RSE. Thirty-two received propofol for a median of 63 hours and a median peak infusion rate of 67 micrograms per kilogram per minute. The other seven patients received other drugs, such as midazolam and pentobarbital.

In the propofol group, three patients had sudden unexplained cardiac arrest, resulting in two deaths. There were no deaths in the other group.

Thirty percent of patients in the propofol group experienced propofol infusion syndrome (PRIS), a serious complication defined b
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Newer Sedative Might Help Patients on Ventilators
2. A high-fat diet could promote the development of Alzheimers
3. Antiseizure Drug Could be Fatal
4. Anti-seizure drug could be fatal
5. Common epilepsy drug could prevent and treat Alzheimers disease
6. The Pink Ribbon That Could Save Your Life
7. With the Economy of the United States at a Turning Point, Health Care Could Be Our Next Serious Crisis ...
8. New Advances Could Battle Cancer Cell by Cell
9. Mayo Clinic estimates new, tiny, super-sensitive probe could cut colon polyp removal in half
10. New test could help catch serious infections in babies
11. New way to control protein activity could lead to cancer therapies
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Sedative Could Be Deadly in People With Seizures
(Date:8/4/2015)... ... 04, 2015 , ... How cool is it to check in at your ... new "Now" feature will soon allow you to do just that. , Ahhaa is ... using the now feature. , Users will soon get to share what inspires them ...
(Date:8/4/2015)... ... August 04, 2015 , ... ... joined the American Association of Tissue Banks (AATB) as an Affiliate Member. ... “to honor donors, and to save and improve lives by promoting the safety, ...
(Date:8/4/2015)... Boca Raton, FL (PRWEB) , ... August 04, ... ... on-site diagnostic testing organization which provides vascular, electrocardiogram (EKG), echocardiogram, and NCV testing, ... momentum but has been successfully identifying previously undiagnosed cardiovascular abnormalities one program at ...
(Date:8/4/2015)... ... August 04, 2015 , ... Angelina Jolie is in it ... of women every year. Dr. Angela DeRosa, DO, MBA, CPE aka “Dr. ... takes the scary unknown out of menopause. , Myth #1: Menopause only affects ...
(Date:8/4/2015)... ... August 04, 2015 , ... ... scheduled for Nov. 3 – 4, 2015, at UC San Diego, will explore ... businesses, improve food access, and manage resources efficiently against the dueling backdrop of ...
Breaking Medicine News(10 mins):Health News:Ahhaa App Soon to Release the "Now" Feature 2Health News:Exsurco Medical Joins AATB as Affiliate Member 2Health News:Colleges and High Schools Across the Country Are Joining the Wimbledon U Team Uncovering Unknown Cardiac Conditions and Promoting Heart Healthy Athletes 2Health News:Colleges and High Schools Across the Country Are Joining the Wimbledon U Team Uncovering Unknown Cardiac Conditions and Promoting Heart Healthy Athletes 3Health News:"Dr. Hot Flash" Debunks the Top 5 Menopause Myths 2Health News:"Dr. Hot Flash" Debunks the Top 5 Menopause Myths 3Health News:Diversity of Urban and Hydroponic Farms of the Future to Highlight Seedstock Annual Conference Field Trip 2Health News:Diversity of Urban and Hydroponic Farms of the Future to Highlight Seedstock Annual Conference Field Trip 3
... say , WEDNESDAY, Nov. 21 (HealthDay News) -- ... certain sounds, such as the sound of a familiar voice ... Washington, Seattle, and the University of California, Los Angeles, ... activity associated with a given sound task can also identify ...
... vascular disease is widespread and often deadly among older ... treat it, according to a new report by a ... Center and Weill Cornell Medical College campuses of NewYork-Presbyterian ... fact that for years, cardiovascular research has focused almost ...
... Revenues Increase 89% to $3.51 Million versus $1.85 ... Million for Q3 of 2006, -- Third ... ... /Xinhua-PRNewswire-FirstCall/ -- China Yingxia,International, Inc. (OTC Bulletin Board: CYXI), a leading provider in ...
... Eclipsys Corporation(R),(Nasdaq: ECLP ), The Outcomes ... Merrill Lynch Health Services Investor Conference,taking place next ... http://www.newscom.com/cgi-bin/prnh/20050209/FLW006LOGO ), Eclipsys executives will present ... a.m. Eastern time. Interested parties are invited to,listen ...
... 21 Shamir,Optical Industry Ltd. (Nasdaq: SHMR ) ... on Tuesday, November 27, 2007, and has,scheduled a conference ... that,morning., The conference call will be broadcast live ... http://www.kcsa.com approximately five minutes before,the conference call ...
... best value for money, study finds , WEDNESDAY, Nov. 21 ... and programs to improve the quality and value of their ... 21 issue of the Journal of the American Medical ... 609 executives of the largest employers in 41 U.S. ...
Cached Medicine News:Health News:Arterial vascular disease underdiagnosed, undertreated in older US women 2Health News:Arterial vascular disease underdiagnosed, undertreated in older US women 3Health News:Arterial vascular disease underdiagnosed, undertreated in older US women 4Health News:China Yingxia International Announces 2007 Third Quarter Financial Results Conference Call 2Health News:China Yingxia International Announces 2007 Third Quarter Financial Results Conference Call 3Health News:China Yingxia International Announces 2007 Third Quarter Financial Results Conference Call 4Health News:China Yingxia International Announces 2007 Third Quarter Financial Results Conference Call 5Health News:Eclipsys to Present at the Merrill Lynch Health Services Investor Conference 2Health News:Eclipsys to Present at the Merrill Lynch Health Services Investor Conference 3Health News:Shamir Optical Industry Ltd. to Host Conference Call Announcing Third Quarter 2007 Earnings Results 2Health News:Most U.S. Companies Do Little to Boost Worker Health Benefits 2
(Date:8/4/2015)... , England , Aug. ... and UK biotechnology company Synairgen plc (LSE: SNG) today announced ... selective inhibitor to the lysyl oxidase type 2 enzyme (LOXL2) ... IPF affects in the region of 100,000 ... global revenues in excess of $1.1 billion by 2017. The LOXL2 ...
(Date:8/4/2015)... On August 3, 2015, a press conference on ... a donation ceremony of a million masks by Wuhan Longfeixiang ... Beijing . Wuhan Longfeixiang ... of Hubei Longfeixiang Industrial Group, which has successfully developed ... Baihe anti-pollution mask, filling the global gap for masks ...
(Date:8/4/2015)... Ill. , Aug. 4, 2015 ... dental supplies and equipment, today announced the acquisition ... Medical Products Laboratories, Inc. ("MPL PDCMD"). MPL PDCMD ... used in preventive and restorative dental procedures. ... expansion of our business in attractive, high-growth segments," ...
Breaking Medicine Technology:Pharmaxis and Synairgen Announce Research Collaboration to Develop LOXL2 Inhibitor For Pulmonary Fibrosis 2Pharmaxis and Synairgen Announce Research Collaboration to Develop LOXL2 Inhibitor For Pulmonary Fibrosis 3Young Innovations Announces Acquisition of Medical Products Laboratories' Professional Dental Contract Manufacturing Division 2
... STOCKHOLM, May 15, 2012 Medivir AB ... infectious diseases, announced today that it has appointed Henric ... commercial activities. Henric, who will have overall responsibility for ... in August 2012 and will be part of the ...
... May 14, 2012 Top leaders representing America,s ... discuss pressing public policy issues affecting job creation and medical ... than $20 billion medical device tax set to begin in ... and Jim Renacci (R-Ohio) joined Walter M Rosebrough, president and ...
Cached Medicine Technology:New Executive Vice President Commercial Appointed 2AdvaMed & BioOhio Discuss MedTech Impact on Ohio's Economy, Job Creation 2AdvaMed & BioOhio Discuss MedTech Impact on Ohio's Economy, Job Creation 3
CleanBox DNA workstation with two 254nm UV lambs & 12-hr timer, 90cm (36-inch)width, single door, 115V (w/crating)...
... tube racks. Its camera-based vision system captures and ... rack, making it ideal for use in automated ... a rack to be read automatically and can ... safety switch prevents a rack from being read ...
... Polypropylene workbench top with powder-coated ... from 25"-34". Available in hundreds ... include shelves, drawers, light fixtures ... an expert in custom building ...
Perforated or Rod Top, Free Standing or Wall Mounted, Storage Cubby Optional, Polypropylene Construction...
Medicine Products: