Navigation Links
Secondhand Smoke Worsens Lung Function in Cystic Fibrosis Patients
Date:1/30/2008

No safe level for sufferers, especially those with genetic variant, study says

TUESDAY, Jan. 29 (HealthDay News) -- Exposure to secondhand smoke worsens lung function in people with cystic fibrosis (CF), especially those with certain genetic variations, say U.S. researchers.

"Despite public health warnings, including a recent U.S. surgeon general's report stating that there is no risk-free level of secondhand smoke exposure, substantial numbers of individuals with CF are exposed to secondhand smoke. Unfortunately, published studies have been inconsistent in associating poorer clinical outcomes in patients with CF with secondhand smoke exposure," the Johns Hopkins University researchers wrote.

The researchers looked at several areas involving secondhand smoke and CF, a fatal disorder that affects more than 30,000 people in the United States. They analyzed data on hundreds of CF patients, and found that secondhand smoke exposure was associated with decreases in all measures of lung function studied. Socioeconomic status did not worsen the relationship between secondhand smoke and reduced lung function.

The researchers also found that certain mutations in the CF-causing gene (CFTR) determine the degree of effect that secondhand smoke has on lung function in CF patients.

The study is published in the Jan. 30 issue of the Journal of the American Medical Association.

"CF may be a good model for uncovering gene-environment interactions that are detrimental to lung function. This study also raises the specter that healthy children bearing certain genetic variants may be at much higher risk for worse outcomes as a result of secondhand smoke exposure," the study authors wrote.

"Demonstration that genetically defined subsets of patients with CF exposed to secondhand smoke in the home have a substantial lifetime reduction in lung function provides potent justification for eradication of cigarette smoke exposure for all individuals with this life-limiting disorder," they concluded.

More information

The March of Dimes has more about cystic fibrosis.



-- Robert Preidt



SOURCE: Journal of the American Medical Association, news release, Jan. 29, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Global Initiative To Protect Children From Secondhand Smoke
2. Novel MRI Technique Shows Secondhand Smoke Damages Lungs
3. Special MRI Shows Secondhand Smoke Damages Lungs
4. Secondhand smoke damages lungs, MRIs show
5. Novel MRI technique shows secondhand smoke damages lungs
6. Indiana Legislature Should Protect All Workers from Secondhand Smoke
7. Secondhand Smoke Hurts Kids Grades
8. Secondhand smoke increases teen test failure
9. Acting Surgeon General Announces National Initiatives to Protect Children by Reducing Exposure to Secondhand Smoke
10. Number of Russian women smokers has doubled since Soviet collapse
11. RealAge Challenges and Cheers Smoke-Free Wannabes in 2008
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Secondhand Smoke Worsens Lung Function in Cystic Fibrosis Patients
(Date:6/27/2016)... ... ... TherapySites, the leading website and online marketing ... Association. This new relationship allows TherapySites to continue to extend their online ... and promotional offers. , "TCA is extremely excited about this new partnership, as ...
(Date:6/27/2016)... ... June 27, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating to ... of individuals in the United States and Canada wear eyeglasses. Once considered to be ... vision and make a fashion statement. Even celebrities use glasses as a way of ...
(Date:6/26/2016)... ... ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect Plugin ... whole new perspective by using the title layers in ProSlice Levels to split-up ... Levels contains over 30 Different presets to choose from. FCPX users can ...
(Date:6/26/2016)... ... June 26, 2016 , ... Many women are ... with endometriosis. These women need a treatment plan to not only alleviate symptoms ... can help for preservation of fertility and ultimately achieving a pregnancy. The specialists ...
(Date:6/25/2016)... ... ... temporary closing of Bruton Memorial Library on June 21 due to a possible lice infestation, ... aspect of head lice: the parasite’s ability to live away from a human host, and ... necessary one in the event that lice have simply gotten out of control. , As ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: ... 510(k) clearance for its Elecsys BRAHMS PCT (procalcitonin) assay ... sepsis or septic shock. With this clearance, Roche is ... a fully integrated solution for sepsis risk assessment and ... with bacterial infection and PCT levels in blood can ...
(Date:6/23/2016)... , June 23, 2016 Bracket , ... launch its next generation clinical outcomes platform, Bracket eCOA (SM) ... held on June 26 – 30, 2016 in ... first electronic Clinical Outcome Assessment product of its kind to ... #715. Bracket eCOA 6.0 is a flexible platform ...
(Date:6/23/2016)... LONDON , June 23, 2016 ... environments  Oticon , industry leaders in ... the launch of Oticon Opn ™, the world,s ... world of possibilities for IoT devices.      ... Opn, Oticon introduces a number of ,world firsts,: ...
Breaking Medicine Technology: