Navigation Links
Secondhand Smoke Worsens Lung Function in Cystic Fibrosis Patients
Date:1/30/2008

No safe level for sufferers, especially those with genetic variant, study says

TUESDAY, Jan. 29 (HealthDay News) -- Exposure to secondhand smoke worsens lung function in people with cystic fibrosis (CF), especially those with certain genetic variations, say U.S. researchers.

"Despite public health warnings, including a recent U.S. surgeon general's report stating that there is no risk-free level of secondhand smoke exposure, substantial numbers of individuals with CF are exposed to secondhand smoke. Unfortunately, published studies have been inconsistent in associating poorer clinical outcomes in patients with CF with secondhand smoke exposure," the Johns Hopkins University researchers wrote.

The researchers looked at several areas involving secondhand smoke and CF, a fatal disorder that affects more than 30,000 people in the United States. They analyzed data on hundreds of CF patients, and found that secondhand smoke exposure was associated with decreases in all measures of lung function studied. Socioeconomic status did not worsen the relationship between secondhand smoke and reduced lung function.

The researchers also found that certain mutations in the CF-causing gene (CFTR) determine the degree of effect that secondhand smoke has on lung function in CF patients.

The study is published in the Jan. 30 issue of the Journal of the American Medical Association.

"CF may be a good model for uncovering gene-environment interactions that are detrimental to lung function. This study also raises the specter that healthy children bearing certain genetic variants may be at much higher risk for worse outcomes as a result of secondhand smoke exposure," the study authors wrote.

"Demonstration that genetically defined subsets of patients with CF exposed to secondhand smoke in the home have a substantial lifetime reduction in lung function provides potent justification for eradication of cigarette smoke exposure for all individuals with this life-limiting disorder," they concluded.

More information

The March of Dimes has more about cystic fibrosis.



-- Robert Preidt



SOURCE: Journal of the American Medical Association, news release, Jan. 29, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Global Initiative To Protect Children From Secondhand Smoke
2. Novel MRI Technique Shows Secondhand Smoke Damages Lungs
3. Special MRI Shows Secondhand Smoke Damages Lungs
4. Secondhand smoke damages lungs, MRIs show
5. Novel MRI technique shows secondhand smoke damages lungs
6. Indiana Legislature Should Protect All Workers from Secondhand Smoke
7. Secondhand Smoke Hurts Kids Grades
8. Secondhand smoke increases teen test failure
9. Acting Surgeon General Announces National Initiatives to Protect Children by Reducing Exposure to Secondhand Smoke
10. Number of Russian women smokers has doubled since Soviet collapse
11. RealAge Challenges and Cheers Smoke-Free Wannabes in 2008
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Secondhand Smoke Worsens Lung Function in Cystic Fibrosis Patients
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... The American ... to become its next President and Chief Executive Officer, succeeding Dr. James C. Puffer ... Elect beginning July 1, 2018 until Dr. Puffer’s retirement at the end of 2018. ...
(Date:10/13/2017)... ... 13, 2017 , ... PurhealthRX , a leading Health and Nutrition Company, ... Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing CBD market by ... be easily incorporated into liquid products, while reducing costs to end users. , The ...
(Date:10/13/2017)... ... ... Lori R. Somekh, founder of the Law Office of Somekh & Associates ... special needs planning attorneys. “Membership in ElderCounsel helps our office remain up to date ... elder law attorneys nationwide,” said Somekh. , ElderCounsel was founded by ...
(Date:10/13/2017)... OBISPO, Calif. (PRWEB) , ... October 13, 2017 , ... ... or dementia. However, many long-term care insurance companies have a waiver for care if ... the 90-day elimination period, when the family pays for care, is often waived, so ...
(Date:10/13/2017)... ... , ... Ellevate Network, the leading network for professional women, brought together some ... at their inaugural Summit in New York City in June. The event was livestreamed ... over 3 million. To watch the Mobilize Women video, click here . ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... PROVIDENCE, R.I. , Sept. 25, 2017 /PRNewswire/ ... immunogenicity assessment, vaccine design, and immune-engineering today announced ... focused on the development of personalized therapeutic cancer ... and has provided exclusive access to enabling technologies ... MSc Eng., MBA will lead EpiVax Oncology as ...
(Date:9/19/2017)... , Sept. 19, 2017   ZirMed Inc ., a ... today announced that it has been ranked #1 by its ... Book™ Rankings 2017 User Survey. ZirMed was recognized as ... large hospitals and medical centers over 200 beds and holds ... healthcare technology user survey history. ...
(Date:9/12/2017)... Sept. 12, 2017  Consumer reviews on the independent review site ... the number one company for hearing aids, ranking it higher than ... brands. ... #1 by Consumers For Hearing Aids ... Hearing is an online store that provides high performance, state-of-the-art, German-engineered ...
Breaking Medicine Technology: