Navigation Links
Second-generation TAVI device -- Lotus Valve -- shows good performance in REPRISE II
Date:5/23/2013

22 May 2013, Paris, France: The Lotus Valve, a second-generation transcatheter aortic valve implantation (TAVI) device, was successfully implanted in all of the first 60 patients in results from REPRISE II reported at EuroPCR 2013, which showed good device performance and low mortality at 30 days.

"First generation TAVI devices provide significant clinical benefit, but there are opportunities for improvement," explained lead author Ian Meredith, Director of MonashHeart, Southern Health and Professor of Medicine, Monash University, Melbourne, Australia. He suggested that these include controlled deployment, simple, precise and atraumatic aortic/ventricular repositioning, no or trivial paravalvular leakage and lower complication rate.

The Lotus Valve System has been designed to address these issues. The valve is pre-attached to the delivery system, which has a simple handle design, and functions early in deployment for controlled, precise positioning. It is fully retrievable and can be repositioned and has an adaptive seal designed to minimise paravalvular leak.

REPRISE II prospectively evaluated the safety and performance of the Lotus Valve System for TAVI in symptomatic patients with severe calcific aortic stenosis considered high risk for surgical valve replacement. Reporting results for the first 60 patients, Meredith told the conference, "Successful valve implantation was achieved in all patients." The primary endpoint for device performance mean aortic valve pressure gradient at 30 days compared to a performance goal of 18mmHg was met. Mean aortic gradient decreased from 47.5+17.2mmHg before the procedure to 11.3+5.2mmHg at 30 days. At the same time effective orifice area increased from 0.6+0.2mmHg to 1.7+0.4mmHg.

"Results showed successful valve implantation in all 60 patients, meeting the primary device performance endpoint," Meredith said. "Importantly, the rate of moderate or greater aortic regurgitation decreased from 18% at the bas
'/>"/>

Contact: Isabelle Uzielli
iuzielli@europcr.com
33-612-233-492
European Society of Cardiology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Second-generation CT scanner substantially reduces radiation exposure
2. Docs Use 3-D Printer to Create Lifesaving Airway Device for Infant
3. Children’s National to Host Symposium on Medical Device Development
4. Walkingspree Expands Device Options with Fitbit to Increase Member Engagement in Corporate Wellness Programs
5. Post-approval TAVI registry shows high rates of device success at 1 year
6. Access MediQuip and WellPoint Renew and Expand National Contract for Implantable Medical Devices
7. New Device May Show Doctors More of the Colon
8. Sleep Apnea Devices Market to reach $19.72 Billion by 2017 - New Report by MarketandMarkets
9. Mississippi Woman’s Injuries Allegedly Caused by Ethicon Inc.’s Transvaginal Mesh Device; Parker Waichman LLP Files Lawsuit
10. PolyU Researchers Develop Novel Brain Training Device to Reconnect the Brain and Paralyzed Limb After Stroke
11. Robotic Surgery Update: Intuitive Surgical Issues Urgent Medical Device Warning Notification
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... Dr. Peter Oettgen, a member of the ... Boston, is the new Deputy Editor of Cardiology for ... experience in the field to the evidence-based, clinical reference ... Oettgen received his medical degree from the University of ... Tufts New England Medical Center. He is the Director ...
(Date:7/24/2014)... The European Omega 3 & Structured Lipids Market ... market in Europe with analysis and forecast of revenue. The ... 2012 to $989.91 million by 2018, at a CAGR of ... of the European omega 3 & structured lipids market report, ... also provides a glimpse of the segmentation of the European ...
(Date:7/24/2014)... Bethesda, MD (PRWEB) July 24, 2014 ... cells circulating in a patient’s blood has been achieved ... team at Massachusetts General Hospital. This is an important ... new approach to selecting the best treatment for each ... said Dr. Haber. “They often acquire new genetic features ...
(Date:7/24/2014)... The European air and missile defense radar market ... expected to register a CAGR of 8.06%, to reach $2.07 ... are the major spenders in the region with a number ... program and multinational (MEADS) program, which has been co-developed by ... of the Europe air and missile defense radar market report, ...
(Date:7/24/2014)... 24 July 2014. LSE Health and the European ... Cardiology (ESC) are pleased to announce the launch ... working in the field of cardiovascular sciences. , ... in Cardiovascular Sciences aims to equip cardiovascular specialists ... skills required to take on advisory, management or ...
Breaking Medicine News(10 mins):Health News:DynaMed™ Names Peter Oettgen, MD as Deputy Editor of Cardiology 2Health News:DynaMed™ Names Peter Oettgen, MD as Deputy Editor of Cardiology 3Health News:Europe Omega 3 & Structured Lipids (Nutraceuticals) Market is Expected to Reach $989.91 Million in 2018 - New Report by MicroMarket Monitor 2Health News:Europe Omega 3 & Structured Lipids (Nutraceuticals) Market is Expected to Reach $989.91 Million in 2018 - New Report by MicroMarket Monitor 3Health News:Europe Omega 3 & Structured Lipids (Nutraceuticals) Market is Expected to Reach $989.91 Million in 2018 - New Report by MicroMarket Monitor 4Health News:New Blood Test Advances Individualized Cancer Therapy and Cuts Down on Need for Painful Biopsies 2Health News:Europe Air and Missile Defense Radar Market is Expected to Reach $2.07 billion in 2020 - New Report by MicroMarket Monitor 2Health News:Europe Air and Missile Defense Radar Market is Expected to Reach $2.07 billion in 2020 - New Report by MicroMarket Monitor 3Health News:Europe Air and Missile Defense Radar Market is Expected to Reach $2.07 billion in 2020 - New Report by MicroMarket Monitor 4Health News:LSE and ESC announce the launch of a new executive-style MSc 2
... in-patient rehabilitation are more likely to land back in ... poorly, show signs of depression and lack social support ... Branch (UTMB) at Galveston. Hospital readmission for older adults ... billion annually. , Among the first of such ...
... , FRIDAY, April 6 (HealthDay News) -- Children ... late may experience more severe symptoms than kids with autism ... These children also may be more likely to inflict ... more severe remain unknown, the study suggested it may have ...
... chemotherapy try to kill tumors by causing oxidative stress in ... protects cancer and other cells from these stresses could one ... them more susceptible to treatment. In the March 23 ... led by USC Professor Kelvin J. A. Davies demonstrated that ...
... FRIDAY, April 6 (HealthDay News) -- Patients with ... exposed to significant levels of radiation from diagnostic imaging ... data from 2,590 patients with gastrointestinal disorders between ... them had undergone diagnostic imaging tests such as computed ...
... News) -- Overuse injuries account for more than one-quarter of ... has found. Women -- especially those who played field ... of the overuse injuries (62 percent). For this study, ... collegiate athletes participating in 16 team sports at the University ...
... ,Airport security screening has increased substantially during the past ... According to the American Academy of Orthopaedic Surgeons ... were performed in the United States. A new ... Checkpoints: How Has Heightened Security Affected Patients," appearing ...
Cached Medicine News:Health News:Predictors identified for rehospitalization among post-acute stroke patients 2Health News:Predictors identified for rehospitalization among post-acute stroke patients 3Health News:Pregnancy Length May Influence Severity of Autism 2Health News:Scientists identify major source of cells' defense against oxidative stress 2Health News:Diagnostic Scans Tied to Radiation Risk for Gastro Patients 2Health News:Overuse Injuries Common Among Female College Athletes 2Health News:Clinical news alert from the American Academy of Orthopaedic Surgeons 2
(Date:7/24/2014)... LAVAL, Quebec , July 24, 2014 /PRNewswire/ ... VRX ) (TSX:VRX) announced today that it ... des marches financiers ("AMF") regarding Allergan, Inc.,s (NYSE: ... investors and to negatively influence the market price ... false and misleading statements regarding Valeant,s business despite ...
(Date:7/24/2014)... , Revenues from continuing operations of ... diluted EPS from continuing operations of $1.08, up 1.9% versus  ... of $0.92, 7% below prior year , Cash from ... , Full year 2014 revenues now expected to be up ... , Full year 2014 adjusted diluted EPS range narrowed to  ...
(Date:7/24/2014)... DIEGO , July 24, 2014   ... announced today a co-promotion agreement with Illumina to ... genome sequence data for precision medicine and clinical ... pharmaceutical companies, through Illumina,s sales force, a solution ... platform for data analytics and storage, and Cypher ...
Breaking Medicine Technology:Valeant Pharmaceuticals Files An Official Complaint With The Autorite Des Marches Financiers About Allergan's False And Misleading Statements 2Valeant Pharmaceuticals Files An Official Complaint With The Autorite Des Marches Financiers About Allergan's False And Misleading Statements 3Valeant Pharmaceuticals Files An Official Complaint With The Autorite Des Marches Financiers About Allergan's False And Misleading Statements 4Valeant Pharmaceuticals Files An Official Complaint With The Autorite Des Marches Financiers About Allergan's False And Misleading Statements 5Valeant Pharmaceuticals Files An Official Complaint With The Autorite Des Marches Financiers About Allergan's False And Misleading Statements 6Quest Diagnostics Reports Second Quarter 2014 Financial Results 2Quest Diagnostics Reports Second Quarter 2014 Financial Results 3Quest Diagnostics Reports Second Quarter 2014 Financial Results 4Quest Diagnostics Reports Second Quarter 2014 Financial Results 5Quest Diagnostics Reports Second Quarter 2014 Financial Results 6Quest Diagnostics Reports Second Quarter 2014 Financial Results 7Quest Diagnostics Reports Second Quarter 2014 Financial Results 8Quest Diagnostics Reports Second Quarter 2014 Financial Results 9Quest Diagnostics Reports Second Quarter 2014 Financial Results 10Quest Diagnostics Reports Second Quarter 2014 Financial Results 11Quest Diagnostics Reports Second Quarter 2014 Financial Results 12Quest Diagnostics Reports Second Quarter 2014 Financial Results 13Quest Diagnostics Reports Second Quarter 2014 Financial Results 14Quest Diagnostics Reports Second Quarter 2014 Financial Results 15Quest Diagnostics Reports Second Quarter 2014 Financial Results 16Quest Diagnostics Reports Second Quarter 2014 Financial Results 17Quest Diagnostics Reports Second Quarter 2014 Financial Results 18Quest Diagnostics Reports Second Quarter 2014 Financial Results 19Quest Diagnostics Reports Second Quarter 2014 Financial Results 20Quest Diagnostics Reports Second Quarter 2014 Financial Results 21Quest Diagnostics Reports Second Quarter 2014 Financial Results 22Cypher Genomics and Illumina Enter Agreement to Facilitate Genomic Biomarker Discovery 2Cypher Genomics and Illumina Enter Agreement to Facilitate Genomic Biomarker Discovery 3
... RIVER, Mass., May 9, 2012  Millstone Medical Outsourcing ... as Vice President of Quality Systems.  As a ... she will be responsible for managing the quality ... all quality associates, and working closely with customers ...
... Md., May 8, 2012 /PRNewswire-iReach/ -- Reimbursement ... device development and commercialization plan. For new product launches ... and quality of life benefits versus comparators to payers, ... ISPOR 2012 highlight these trends:  IMPACT OF ...
Cached Medicine Technology:Millstone Medical Outsourcing Hires New Vice President Quality 2Upcoming Presentations on Global Market Access Issues and Trends in Health Economics and Outcomes Research at ISPOR 2012 by Novel Health Strategies 2
Inquire...
The new Gemini EM microplate spectrofluorometer builds on the successful Gemini platform. This next generation reader incorporates all of the high performance features of the Gemini XS with new capab...
The Fluoroskan Ascent FL is equipped with both fluorometric and luminometric measurement technologies, providing a full coverage for fluorometric, glow and flash luminometric applications even in the...
... from Berthold Technologies, has been designed ... measurement modes to support academic and ... ratio measurements plus top and bottom ... for any researcher using fluorescence in ...
Medicine Products: