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Second door discovered in war against mosquito-borne diseases
Date:7/8/2013

f a mosquito sodium channel for the first time," said Ke Dong, MSU insect toxicologist and neurobiologist and the paper's senior author. "Another lead author of this study, Yoshiko Nomura, dedicated nearly one year to make this happen, which allowed Dr. Du to perform electrophysiological experiments with the clone."

The team then spent nearly two years to discover the new pyrethroid-binding site, she added.

The revelation not only explains much of pyrethroid resistance found in mosquito populations worldwide, but also helps answer why they affect insects but not humans and other mammals. Since this is a growing issue with cockroaches, bedbugs, fleas, potato beetles and other crop pests, the discovery could lead to benefits for the pest-control industry and farming.

"Our finding may ultimately improve global prediction and monitoring of pyrethroid resistance in mosquitoes and other arthropod pests," Dong said. "It could have broad impacts in agriculture and medicine that affect people's lives, especially in developing countries."


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Contact: Layne Cameron
layne.cameron@cabs.msu.edu
517-353-8819
Michigan State University
Source:Eurekalert

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