Navigation Links
Second breast cancer may be greater than thought for high-risk women without BRCA mutations
Date:5/4/2008

New York, NY A preliminary analysis of ongoing research suggests that high-risk women with breast cancer who do not have a BRCA1/2 mutation may face a greater chance for developing a second breast cancer than previously thought. With the increased risk of cancer in these women, should sentinel node biopsy be considered at the time of prophylactic mastectomy, and how can women best be counseled after these findings?

The increased risk of developing breast cancer is already understood for women with the disease who test positive for a BRCA1 or 2 mutation. Many of these women choose to have their breast(s) surgically removed (prophylactic mastectomy) to reduce their risk of developing breast cancer or developing a second breast cancer The role of sentinel node biopsy remains controversial in this group.

"We know more about counseling women regarding prophylactic mastectomy if they have a BRCA mutation," says Shawna C. Willey, MD, FACS, a member of the Breast Cancer Program at the Lombardi Comprehensive Cancer Center and director of the Betty Lou Ourisman Breast Health Center at Georgetown University Hospital. "In high-risk women who have cancer but dont have a known mutation, we generally advise that the risk of developing a second cancer in the same or opposite breast is lower than it is for women who test positive for a mutation. This latest analysis has us re-thinking our approach."

Willey, the incoming president of the American Society of Breast Surgeons, is the lead author of the study presented today at the societys annual meeting in New York City.

The study included women in a familial cancer registry at Lombardi who were enrolled between 1998 and 2007. The registry participants had a least a 10 percent probability of carrying a BRCA1/2 mutation based on personal or family history of cancer. The cohort for the study included 119 women. 74 women had a BRCA mutation (group 1) and 45 did not test positive for the m
'/>"/>

Contact: Karen Mallet
km463@georgetown.edu
414-312-7085
Georgetown University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. 9/11 Counselors at Risk for Secondary Trauma
2. American Pacific to Release Financial Results and Hold Fiscal 2008 Second Quarter Investor Teleconference
3. CryoCath to Hold Second Quarter 2008 Conference Call and Webcast
4. Landauer, Inc. Reports Record Results for Second Quarter
5. Hill-Rom Holdings, Inc. Invites You to Join Its Fiscal 2008 Second Quarter Earnings Webcast
6. NBTY Reports Second Quarter Results
7. Aflac Incorporated Announces First Quarter Results, Declares Second Quarter Cash Dividend
8. BD Announces Results for Second Fiscal Quarter
9. Study: Counseling trauma victims causes secondary trauma
10. Lilly Declares Second-Quarter Dividend
11. NBTY to Web Cast Fiscal Second Quarter Conference Call
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... WASHINGTON, Aug. 21 Meridian International,Center today announced ... Susan Blumenthal, M.D. will lead Meridian,s new Global ... key initiative of Meridian,s,programs that include world affairs ... Leadership Programs, and arts and,cultural activities., "Today, ...
... Texas A universal vaccine effective against ... phase of testing, according to Dr. Christine Turley of ... is director of clinical trials and clinical research at ... the study,s principal investigator, said that VaxInnate,s M2e universal ...
... fresh website highlight stronger focus on expanding market for UME/GME ... ... (PRWEB) August 21, 2008 -- one45 Software, a leading provider ... Software Inc. (CRX:TSX.V), announced today the availability of a rebranded ...
... Law immediately affects the operations of more than 500 ... ... nationwide, PORTLAND, Ore., Aug. 20 When the House ... Medicare beneficiaries, they also established stricter,requirements for Medicare Advantage plans during ...
... stands most likely to illegally sell alcohol, study finds , , ... or already drunk, many vendors in American sports stadiums will ... , That,s the finding from a new study that suggests ... who shouldn,t drink. , People who clearly appeared underage were ...
... Fourteen physicians who have been,part of Commonwealth Medical ... and service they provide to their patients by joining ... and we are delighted they,have decided to join our ... officer. "We look forward to working with,them to support ...
Cached Medicine News:Health News:Former U.S. Assistant Surgeon General, Dr. Susan Blumenthal, to Lead Meridian International Center's Global Health Program 2Health News:Cytiva's one45 Software Rebrands Healthcare Education Administration Products 2Health News:Cytiva's one45 Software Rebrands Healthcare Education Administration Products 3Health News:Cytiva's one45 Software Rebrands Healthcare Education Administration Products 4Health News:Medicare Advantage Plans Struggle to Comply With New Federal Law 2Health News:Underaged, Inebriated Easily Get Drinks at Stadiums 2Health News:Commonwealth Medical Group Physicians to Join Aurora Health Care 2
(Date:12/17/2014)... and RALEIGH, N.C. , Dec. ... LLC (CTMC), and Integrated Clinical Trial Services, LLC ... retention for clinical trials announce that they have ... Marketing Services (i-CTMS). i-CTMS will provide a broad ... pharmaceutical, biotechnology and medical device companies. ...
(Date:12/15/2014)... , December 15, 2014 ... Am 19. und 20. Februar sind alle ... SAFE MEDICINE ECOSYSTEM PARTNER PROGRAMM ™ 2015 ... besuchen. Diese Tagung soll dazu ... Möglichkeit geben, die neue profitablen Unternehmensdienstleistungen, die ...
(Date:12/15/2014)... DUBLIN , Dec. 12, 2014 Research and ... addition of the "Electrocardiogram (ECG) Devices - Global ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... reach US$330 million by 2016. The North ... the global market share while Europe ...
Breaking Medicine Technology:Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 2Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 3Symposium über Aegates Ecosystem-Partner-Programm für sichere Medikamente vom 19. - 20. Februar 2015 in Amsterdam 2Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 2Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 3Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 4
... 2012 The kids are outside playing soccer, baseball, or ... next thing parents know, there is a trip to the ... can heal properly is the refined work of physicians and ... child,s day-to-day life while injured. A common problem parents face ...
... this year,s Annual Scientific Meeting of the American ... Grunenthal will present results from clinical studies utilizing ... INTAC™ is designed to be crush-resistant and to ... INTAC™ to prescription opioid drugs is considered an ...
Cached Medicine Technology:Warm Weather Means Active Children May Be Prone To More Injuries 2INTAC™ Technology Combats Misuse of Extended Release Drugs 2
Straight heavy shafts with 7 mm tying surface. Wide serrated handle, polished finish. Overall length 4.2 inches....
Tying forceps with 6.5 mm tying platform. Round handle with flats provide flexibility of round handle with the stability of a flat handle. Straight shafts. Overall length 3.9 inches....
Curved shafts with 4 mm tying platform. Serrated handle with dull finish. Manufactured in titanium. Overall length 3.3 inches....
Straight 6 mm platform. McPherson handle. Manufactured in titanium. Overall length 3.3 inches....
Medicine Products: