Navigation Links
Second breast cancer may be greater than thought for high-risk women without BRCA mutations
Date:5/4/2008

New York, NY A preliminary analysis of ongoing research suggests that high-risk women with breast cancer who do not have a BRCA1/2 mutation may face a greater chance for developing a second breast cancer than previously thought. With the increased risk of cancer in these women, should sentinel node biopsy be considered at the time of prophylactic mastectomy, and how can women best be counseled after these findings?

The increased risk of developing breast cancer is already understood for women with the disease who test positive for a BRCA1 or 2 mutation. Many of these women choose to have their breast(s) surgically removed (prophylactic mastectomy) to reduce their risk of developing breast cancer or developing a second breast cancer The role of sentinel node biopsy remains controversial in this group.

"We know more about counseling women regarding prophylactic mastectomy if they have a BRCA mutation," says Shawna C. Willey, MD, FACS, a member of the Breast Cancer Program at the Lombardi Comprehensive Cancer Center and director of the Betty Lou Ourisman Breast Health Center at Georgetown University Hospital. "In high-risk women who have cancer but dont have a known mutation, we generally advise that the risk of developing a second cancer in the same or opposite breast is lower than it is for women who test positive for a mutation. This latest analysis has us re-thinking our approach."

Willey, the incoming president of the American Society of Breast Surgeons, is the lead author of the study presented today at the societys annual meeting in New York City.

The study included women in a familial cancer registry at Lombardi who were enrolled between 1998 and 2007. The registry participants had a least a 10 percent probability of carrying a BRCA1/2 mutation based on personal or family history of cancer. The cohort for the study included 119 women. 74 women had a BRCA mutation (group 1) and 45 did not test positive for the m
'/>"/>

Contact: Karen Mallet
km463@georgetown.edu
414-312-7085
Georgetown University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. 9/11 Counselors at Risk for Secondary Trauma
2. American Pacific to Release Financial Results and Hold Fiscal 2008 Second Quarter Investor Teleconference
3. CryoCath to Hold Second Quarter 2008 Conference Call and Webcast
4. Landauer, Inc. Reports Record Results for Second Quarter
5. Hill-Rom Holdings, Inc. Invites You to Join Its Fiscal 2008 Second Quarter Earnings Webcast
6. NBTY Reports Second Quarter Results
7. Aflac Incorporated Announces First Quarter Results, Declares Second Quarter Cash Dividend
8. BD Announces Results for Second Fiscal Quarter
9. Study: Counseling trauma victims causes secondary trauma
10. Lilly Declares Second-Quarter Dividend
11. NBTY to Web Cast Fiscal Second Quarter Conference Call
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2015)... ... September 01, 2015 , ... ... Nurse Scholar-in Residence at the Institute of Medicine (IOM) of the National Academies. ... at Columbia University School of Nursing. A member of the Institute of Medicine ...
(Date:9/1/2015)... ... September 01, 2015 , ... USA Medical Card, a leading ... to coincide with back-to-school and the start of “sick season” for many households ... school children are sick an average of 8 to 12 times each school ...
(Date:9/1/2015)... ... September 01, 2015 , ... ... Recovery Network, the Premier Outcomes-Driven Provider Network. It is the first-ever, standardized, ... to the provision of quality addiction treatment and the utilization of resources ...
(Date:9/1/2015)... Buffalo, New York (PRWEB) , ... September 01, 2015 , ... ... as one of the Super Lawyers 2015 for his third consecutive year in a ... his achievements and accomplishments of helping people. , Born in Niagara Falls, New York, ...
(Date:9/1/2015)... ... September 01, 2015 , ... Specialty Technical Publishers (STP) ... Audit Protocol Consortium (IAPC) EHS audit protocol for the European Union. Leading companies ... their EHS regulatory obligations and rapidly collect, share, archive, and export audit findings ...
Breaking Medicine News(10 mins):Health News:Columbia Nursing’s Suzanne Bakken Named Distinguished Institute of Medicine Nurse Scholar-in-Residence 2Health News:USA Medical Card Launches New FAQ Video During Back-to-School 2Health News:MAP Health Management Launches the MAP Recovery Network 2Health News:Specialty Technical Publishers (STP) and Specialty Technical Consultants(STC) Publish Environmental, Health & Safety (EHS) Audit Protocol for the European Union 2Health News:Specialty Technical Publishers (STP) and Specialty Technical Consultants(STC) Publish Environmental, Health & Safety (EHS) Audit Protocol for the European Union 3Health News:Specialty Technical Publishers (STP) and Specialty Technical Consultants(STC) Publish Environmental, Health & Safety (EHS) Audit Protocol for the European Union 4
... 10 ThirdForce, the UK,s leading,e-learning provider, now acts as ... care home companies in the UK, Barchester Healthcare.,ThirdForce will support ... Barchester,s quality provision of care and customer,service. , ... the success of the,Barchester business; a group that currently cares ...
... bacteria,s structure, , WEDNESDAY, June 10 (HealthDay News) -- ... a vacation. , Now, researchers have figured out how ... coli, or ETEC -- are able to make ... or "fimbriae" to attach, or bind, to the intestinal ...
... billion kilograms of toxic pollutant releases and transfers reported ... just 30 substances from 15 industrial sectors across the ... tri-national pollution report from the Commission for Environmental Cooperation ... most complete picture of pollution reporting from North American ...
... to teenagers after their sixteenth birthdays and French children ... U.S. parents who follow this relaxed European example, believing ... careful -- it may increase the likelihood that their ... Abar, graduate student, human development and family studies and ...
... Can $167 million in provincial funding make a difference ... results from the Systems Enhancement Evaluation Initiative (SEEI), the ... appropriate community mental health services. But, the research also ... in need. Led by the Centre for ...
... diagnosed in the late and irreversible stages, when treatment ... progression of disease. Because osteoarthritis is a widespread problem ... a precise way to diagnose the disease early and ... biomarkers in dogs for early diagnosis of osteoarthritis, which ...
Cached Medicine News:Health News:Barchester Healthcare Gains Skills for Life With ThirdForce 2Health News:Barchester Healthcare Gains Skills for Life With ThirdForce 3Health News:Finding May Lead to Vaccine for Traveler's Diarrhea 2Health News:Latest trinational report presents most complete picture of North American industrial pollution 2Health News:Latest trinational report presents most complete picture of North American industrial pollution 3Health News:Zero tolerance alcohol policy good choice for parents 2Health News:Evaluation shows $167 million investment improves community mental health system, but many still in need 2Health News:Early detection of osteoarthritis in dogs could open doors for a cure 2
(Date:9/1/2015)... Pa. , Sept. 1, 2015 ... fully integrated specialty pharmaceutical company focused on discovering, ... that researchers will be  presenting scientific data on ... an abuse-deterrent, extended-release, oral morphine product candidate, and ... development, at PainWeek 2015 to be ...
(Date:9/1/2015)... - The ... egistry data presented at ESC Congress 2015 ... the evolution of manag ing AF in everyday ...   The first-ever two-year outcomes from the Global Anticoagulant Registry ... that all-cause death was the most frequent major event in more than 17,000 ...
(Date:9/1/2015)... Calif. , Sept. 1, 2015 /PRNewswire/ ... cardiovascular image management market, Frost & Sullivan ... 2015 European Frost & Sullivan Award for ... -based PMI has designed innovative and easy-to-use ... deliver precise and reproducible quantitative results for ...
Breaking Medicine Technology:Egalet Announces Scientific Presentations at PainWeek 2015 Meeting 2Egalet Announces Scientific Presentations at PainWeek 2015 Meeting 3Egalet Announces Scientific Presentations at PainWeek 2015 Meeting 4Egalet Announces Scientific Presentations at PainWeek 2015 Meeting 5Egalet Announces Scientific Presentations at PainWeek 2015 Meeting 6Global Atrial Fibrillation Registry Presents Two-Year Outcomes Data In More Than 17,000 Newly Diagnosed AF Patients 2Global Atrial Fibrillation Registry Presents Two-Year Outcomes Data In More Than 17,000 Newly Diagnosed AF Patients 3Global Atrial Fibrillation Registry Presents Two-Year Outcomes Data In More Than 17,000 Newly Diagnosed AF Patients 4Global Atrial Fibrillation Registry Presents Two-Year Outcomes Data In More Than 17,000 Newly Diagnosed AF Patients 5Global Atrial Fibrillation Registry Presents Two-Year Outcomes Data In More Than 17,000 Newly Diagnosed AF Patients 6Global Atrial Fibrillation Registry Presents Two-Year Outcomes Data In More Than 17,000 Newly Diagnosed AF Patients 7Global Atrial Fibrillation Registry Presents Two-Year Outcomes Data In More Than 17,000 Newly Diagnosed AF Patients 8Global Atrial Fibrillation Registry Presents Two-Year Outcomes Data In More Than 17,000 Newly Diagnosed AF Patients 9Frost & Sullivan Applauds Pie Medical Imaging for Highly Innovative Quantitative Software for Cardiovascular Diagnosis 2Frost & Sullivan Applauds Pie Medical Imaging for Highly Innovative Quantitative Software for Cardiovascular Diagnosis 3Frost & Sullivan Applauds Pie Medical Imaging for Highly Innovative Quantitative Software for Cardiovascular Diagnosis 4Frost & Sullivan Applauds Pie Medical Imaging for Highly Innovative Quantitative Software for Cardiovascular Diagnosis 5
... organizer UBM Live announced strong booking levels ... buyers and sellers of high value chemistry. 248 exhibitors ... takes place from February 19th to 22nd of 2013 ... fine and specialty chemical companies that have signed up ...
... 15, 2012  Adamas Pharmaceuticals, Inc., a privately held ... End-of-Phase 2 meeting with the FDA to discuss ... conducted for the registration of Arimenda (memantine HCl ... once-daily fixed dose combination of extended release memantine ...
Cached Medicine Technology:Strong Booking Levels For Informex 2013 2Strong Booking Levels For Informex 2013 3Adamas Pharmaceuticals Announces Successful End-of-Phase 2 Meeting with FDA for Arimenda™ 2Adamas Pharmaceuticals Announces Successful End-of-Phase 2 Meeting with FDA for Arimenda™ 3
... All Infectious Disease ELISA ... well format. Also included ... positive and negative controls, ... stop solution. Use an ...
InBios' Trypanosoma cruzi (chagas disease) is an ELISA system for the detection of antibodies to T.cruzi derived TcF antigen in human serum or plasma This test is intended for professional in vitro d...
... chain reaction (PCR) technology, the worlds leading ... component of Roches blood screening assays and ... of selected unique regions of genetic material ... (that is, to detectable levels) in only ...
The OneTouch Flexx Professional Blood Glucose Monitoring System with OneTouchPro Test Strips sets the standard for safety and convenience with unique off-meter sample application and a wide range of ...
Medicine Products: