Navigation Links
Second Heart Attack Not Always Tied to Original Blockage

By Maureen Salamon
HealthDay Reporter

WEDNESDAY, Jan. 19 (HealthDay News) -- Twenty percent of heart attack patients stand a good chance of suffering a second attack over the following three years, an event that is nearly as likely to be caused by a new blockage as by the original one, a new study suggests.

Researchers from Columbia University Medical Center/New York-Presbyterian Hospital also found that most new blockages responsible for second heart attacks had appeared mild during the initial cardiac workup.

A group of 697 patients with acute coronary syndrome -- an umbrella term describing chest pain due to poor blood supply to the heart -- underwent angiogram and ultrasound imaging tests to track artery blockages called lesions. The group, three-quarters of whom were men, was followed for a median of 3.4 years.

"The first thing is, those who come in with a heart attack or a threatened heart attack and get a successful angiogram . . . have very low chances of a heart attack over the next three years," said study author Dr. Gregg W. Stone, director of cardiovascular research and education at New York-Presbyterian/Columbia. "That's the good news."

"I think the whole thing was certainly illustrative," Stone added. "It gave us a lot of insights into the history of atherosclerosis we didn't have."

Lesions that caused subsequent cardiac events -- including death, heart attack or progressive angina pain -- were identified as previously treated or untreated. About 20 percent of patients suffered later cardiac events over a three-year period, according to the study.

So-called "culprit" lesions, which caused the first heart attack, were found to be responsible for 12.9 percent of later events, while "non-culprit" lesions that had previously appeared mild on angiograms caused 11.6 percent of later events.

"If you do have those hidden blockages . . . they're going to obviously intensify," Stone said. "Now the question is, is there anything we can do to prevent them from becoming symptomatic in the future?"

The study is reported in the Jan. 20 issue of the New England Journal of Medicine.

Dr. Gregg C. Fonarow, a professor of cardiology at the University of California, Los Angeles, said he thought the research was well-done and that it confirms prior studies that identified lesions that went on to cause successive cardiac events.

The message of the study, Fonarow said, is that heart disease needs to be treated systemically with diet, exercise and medication, in addition to treating detectable blockages.

"Just because you have a normal stress test doesn't mean you're out of the woods. Fundamental treatment needs to focus on treating the underlying disease," Fonarow said.

"There's no question treating the culprit lesion is critical," he added. "Even in these patients with known disease, there are further opportunities to improve their condition. There are many other lesions that don't show up on the angiogram . . . that are definitely amenable to the cardiovascular protection of [lifestyle and medication]."

More information

Visit the American Heart Association for more on heart attacks.

SOURCES: Gregg W. Stone, M.D., director, cardiovascular research and education, New York-Presbyterian Hospital/Columbia University Medical Center, New York City; Gregg C. Fonarow, M.D., professor, cardiology, University of California, Los Angeles; Jan. 20, 2011, New England Journal of Medicine

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Secondhand Smoke Tied to High Blood Pressure in Kids
2. Secondhand television exposure linked to eating disorders
3. Second Brain Death Exam Unnecessary, Study Finds
4. Secondhand Smoke May Put Kids at Risk for Diseases
5. New Drug, Pradaxa, May Prevent Second Stroke in Certain Heart Patients
6. Denser Breasts Raise Odds of Second Breast Cancer, Study Finds
7. Better marker for breast cancer may reduce need for second surgeries
8. Urgent steps needed to tackle inadequate support for women with secondary breast cancer
9. Radiation exposure poses similar risk of first and second cancers in atomic bomb survivors
10. Vitamin B May Not Guard Against Second Stroke, Heart Attack
11. Vanishing bile duct syndrome secondary to anti-retroviral therapy in HIV
Post Your Comments:
Related Image:
Second Heart Attack Not Always Tied to Original Blockage
(Date:11/24/2015)... ... November 24, 2015 , ... Eric C. Seidel, DMD and ... of the revolutionary BIOLASE WaterLase iPlus 2.0™ system. This advanced laser technology uses ... a dentist in Gettysburg, PA . From routine visits to cosmetic treatments, ...
(Date:11/24/2015)... ... November 24, 2015 , ... New patients who wish to seek ... dental implants at her Mississauga, ON practice. Dr. Williams has been providing ... of dental implants. , Missing teeth can lead to a variety of complications ...
(Date:11/24/2015)... Dallas, Texas (PRWEB) , ... November 24, 2015 , ... ... of all charitable donations are made in the last five weeks of the year ... #GivingTuesday was created in 2012 to connect the nation’s charities with those individuals who ...
(Date:11/24/2015)... , ... November 24, 2015 , ... In an ... restrictions and variables that determine which patients are or are not eligible for bariatric ... have a BMI over 40, are more than 100 pounds overweight, or have a ...
(Date:11/24/2015)... ... November 24, 2015 , ... DMG Productions announced that they will feature ... quarter 2016 via Discovery Channel. Dates and show times TBA. , Aphria, Inc., is ... the business of producing and supplying medical marijuana pursuant to the Marijuana for Medical ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... 2015  ARKRAY USA , Inc., ... evidence demonstrating the accuracy of its blood glucose meter ... Resistance, Diabetes and Cardiovascular Disease in Los ... GLUCOCARD ® 01 meter and the Assure ® ... ability to accurately measure glucose levels in blood is ...
(Date:11/25/2015)... Israel , November 25, 2015 ... KTOV ) (TASE: KTOV), a biopharmaceutical company focused ... treatment of various clinical conditions, today announced the closing ... American Depository Shares ( ADSs ), each representing 20 ... up to 3,158,900 ADSs. The ADSs and warrants were ...
(Date:11/25/2015)... DIEGO , Nov. 25, 2015  Trovagene, Inc. ... diagnostics, today announced that Chief Executive Officer Antonius Schuh, ... the 27 th Annual Piper Jaffray Healthcare Conference. ... at the New York Palace Hotel in ... at 1:30 p.m. EST. Mr. Schuh will be available ...
Breaking Medicine Technology: