Navigation Links
Seaweed and fireflies brew may guide stem cell treatment for peripheral artery disease
Date:3/10/2009

An unlikely brew of seaweed and glow-in-the-dark biochemical agents may hold the key to the safe use of transplanted stem cells to treat patients with severe peripheral arterial disease (PAD), according to a team of veterinarians, basic scientists and interventional radiologists at Johns Hopkins.

In a preliminary "proof of concept" study in rabbits, Johns Hopkins scientists safely and successfully delivered therapeutic stem cells via intramuscular injections and then monitored the stem cells' viability once they reached their targets.

A report of the study by Johns Hopkins radiologists is scheduled for presentation at the Society of Interventional Radiology's 34th annual scientific meeting March 10.

Stem cells hold promise in treating PAD by reconstituting or increasing the number of blood vessels to replace or augment those choked off by plaque buildup. A chronic condition that can lead to amputations and even death, PAD is marked by vastly reduced circulation of blood in vessels feeding the legs and other "peripheral" body parts, and affects as many as 10 million Americans. Many cases can be treated with angioplasty or stents, similar to approaches used in coronary artery disease, but for some patients with extensive disease conventional treatment is not feasible, researchers say.

Among the technical hurdles to improving blood flow in such patients, according to Dara L. Kraitchman, V.M.D., Ph.D., associate professor of radiology at Johns Hopkins, is a means of telling doctors whether injected stem cells are staying alive and reaching the right targets to grow and develop into the needed new tissue.

This is critical, Kraitchman says, because the body's own immune defenses may recognize the potentially helpful donor stem cells as foreign invaders and try to destroy them, and also because traditional radioactive labeling agents, or tracers, which are normally used to track cells, can be toxic to stem cells.

<
'/>"/>
Contact: Gary Stephenson
gstephenson@jhmi.edu
410-955-5384
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Fireflies glow helps UT Southwestern researchers track cancer drugs effectiveness
2. FRC Responds to President Obamas Misguided Decision on Stem Cell Science
3. HEROES Grants, Education Guide Support Youth Leaders Addressing Childhood Obesity Epidemic
4. The REACH Institute: Best Practice Guidelines Address Mental Health Needs of Youth in Care
5. New Book Exposes Junk Science, Conflicts of Interest, Disease Guidelines Affecting Millions
6. IPRO QIO Uses Milliman Care Guidelines(R) for Medicare Reviews in New York State
7. American College of Gastroenterology Issues Updated Colorectal Cancer Guidelines
8. New CME guidelines advise paradigm shift in physician education
9. Recovery Audit Contractor HealthDataInsights Licenses Milliman Care Guidelines(R)
10. American Academy of Dermatology Issues New Guidelines For The Management of Psoriasis With Topical Therapies
11. New tool guides doctors to save cancer patients fertility
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2015)... With the approaching summer shaping up as ... United States, people will spend an increasing amount of ... of air conditioning, a recent CBS News article* warned ... allergic reactions. Fresh water advocate Sharon Kleyne, host of ... will discuss the potential side effects of air conditioning ...
(Date:6/2/2015)... Newport Beach, CA (PRWEB) June 02, 2015 ... laboratory products and services, announced today that the ... is now available in print and online. The ... Issue 2, as well as past issues of ... all popular desktop, tablet and smartphone platforms by ...
(Date:6/2/2015)... Red Bank, New Jersey (PRWEB) June 02, 2015 ... Group, New Jersey’s largest nonprofit provider of home ... the appointment of its President and CEO, Steve ... of America's (VNAA) Board of Directors. , ... VA, that supports, promotes and advances mission driven, ...
(Date:6/2/2015)... (PRWEB) June 02, 2015 Residents of ... they walk…or swim, take a fitness class, do yoga, ... choice. In preparation for the Alzheimer’s Association’s Walk ... and staff will take part in a challenge to ... (LCS), Monarch Landing’s management company. , While the walk ...
(Date:6/2/2015)... Cincinnati, OH (PRWEB) June 02, 2015 ... healthcare ministry serving Ohio and Kentucky – has devoted ... Be Well videos to skin cancer prevention. One in ... concise video on Mercy Health’s YouTube channel, a Mercy ...     What are the main causes of skin cancer? ...
Breaking Medicine News(10 mins):Health News:Air conditioning may contribute to dry eye, dehydration and allergies warns fresh water advocate Sharon Kleyne 2Health News:Air conditioning may contribute to dry eye, dehydration and allergies warns fresh water advocate Sharon Kleyne 3Health News:Glidewell Laboratories Releases New Issue of Restorative Dentistry Magazine Chairside in Print and Online 2Health News:Glidewell Laboratories Releases New Issue of Restorative Dentistry Magazine Chairside in Print and Online 3Health News:Steve Landers, MD, MPH, President and CEO of VNA Health Group Appointed to VNAA Board of Directors 2Health News:Steve Landers, MD, MPH, President and CEO of VNA Health Group Appointed to VNAA Board of Directors 3Health News:Monarch Landing Takes 60-Day Exercise Challenge to Combat Alzheimer’s 2Health News:Monarch Landing Takes 60-Day Exercise Challenge to Combat Alzheimer’s 3Health News:Video provides helpful information about skin cancer prevention 2
... study conducted by researchers say it is a misconception ... older or housebound people.// ,Researchers examined 150 ... levels of vitamin D. Among the participants, all African-American, ... D deficiencies, as were all patients younger than 30. ...
... A pitch-black room may be the healthiest environment for your ... at night // may put children at risk for ... to disrupt the circadian rhythm and suppress the production of ... been shown to protect DNA from oxidative damage. Once damaged, ...
... study shows sinusitis in asthma patients tends to be ... suggest patients // can have dramatic improvement in symptoms ... is used. ,In the study patients with asthma ... polyps, olfactory dysfunction, and nasal congestion compared to patients ...
... new study shows moderate consumption of alcohol may cut ... arteries.// Researchers evaluated 225 men after they had undergone ... open blocked arteries with a stent. Less traumatic than ... cause inflammation resulting in renarrowing of the artery, usually ...
... study researchers say the antidepressant duloxetine, also known ... fibromyalgia in women . Duloxetine works by stopping ... of the brain’s neurotransmitters that are linked to ... that is characterized by body pain, muscle tenderness, ...
... cluster of risk factors known as metabolic syndrome is ... risk factors. // ,Metabolic syndrome has been ... coronary heart disease. Metabolic syndrome includes looking at factors ... has two different definitions including one by the National ...
Cached Medicine News:
(Date:6/2/2015)... 2, 2015  Ovatemp proudly launches the only women,s health ... entire reproductive life cycle, from puberty through menopause. With ... basal thermometer and connected Ovatemp app to naturally improve ... or avoid pregnancy altogether. The ONDO can now be ... app can be downloaded from the App Store ...
(Date:6/2/2015)...   EMD Millipore , the Life Science ... Germany , today introduced a ... media into granules, accelerating solubility and improving flowability ... convenient to use, allowing biopharmaceutical manufacturers to further ... http://photos.prnewswire.com/prnh/20150531/219975 Photo - http://photos.prnewswire.com/prnh/20150531/219642 ...
(Date:6/2/2015)... , June 2, 2015 ... de la mejora  de 7,9 meses en la ... los pacientes con cáncer colorrectal metastático inoperable (mCRC) ...   SIR-Spheres® Y-90 más quimioterapia    ... SIR-Spheres Y-90 directamente al hígado con la quimioterapia ...
Breaking Medicine Technology:Techstars-backed Startup Ovatemp Launches the Only Complete, Personalized Fertility Management Platform for Women 2EMD Millipore Introduces Compaction Technology to Improve Solubility and Facilitate Handling of Cell Culture Media Used in Biopharmaceutical Production 2EMD Millipore Introduces Compaction Technology to Improve Solubility and Facilitate Handling of Cell Culture Media Used in Biopharmaceutical Production 3Se presenta el estudio SIRFLOX en la reunión anual ASCO 2015 2Se presenta el estudio SIRFLOX en la reunión anual ASCO 2015 3Se presenta el estudio SIRFLOX en la reunión anual ASCO 2015 4Se presenta el estudio SIRFLOX en la reunión anual ASCO 2015 5Se presenta el estudio SIRFLOX en la reunión anual ASCO 2015 6Se presenta el estudio SIRFLOX en la reunión anual ASCO 2015 7Se presenta el estudio SIRFLOX en la reunión anual ASCO 2015 8
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: