Navigation Links
Searching for therapeutic synergy in primary effusion lymphoma
Date:5/1/2013

Primary effusion lymphoma (PEL) is a rare, fatal form of aggressive B-cell lymphoma caused by Kaposi's sarcoma-associated herpesvirus (KSHV). The disease most commonly occurs in immunocompromised patients, such as those with HIV and the elderly. Because current treatment options are not effective, there is a great need for new PEL therapies. In this issue of the Journal of Clinical Investigation, Juan Carlos Ramos and colleagues at the University of Miami used an immunocompromised mouse model of PEL to determine the efficacy of Bortezomib/Vorinostat combination therapy, two drugs that are currently being used to treat multiple myeloma and cutaneous T cell lymphoma, respectively. They found that this treatment combination reactivated virus-induced cell lysis and induced PEL cell death, increasing the lifespan of mice with PEL tumors. These findings indicate that this drug combination could potentially be beneficial in immunocompromised patients with KSHV-associated malignancies.


'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related medicine news :

1. MP3 song-searching can increase risk for drivers
2. LA BioMeds Dr. Patricia Dickson researching treatments for neurodegenerative disorders
3. Novel gene-searching software improves accuracy in disease studies
4. GW professor researching ways to improve human tissue dissection, reduce blood transfusions
5. Targeted therapeutics for colon cancer to be presented at AACR meeting
6. The Ludwig Institute for Cancer Research announces launch of iTeos Therapeutics SA
7. 5 more pharmaceutical companies join NIH initiative to speed therapeutic discovery
8. FORMA Therapeutics teams with TGen Drug Development
9. Device implanted in brain has therapeutic potential for Huntingtons disease
10. Enzyme offers new therapeutic target for cancer drugs
11. Lauren Sciences LLCs research team at Ben-Gurion University awarded Campbell Foundation grant to develop a V-Smart therapeutic for neuro-HIV
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... ... May 24, 2016 , ... ... services today announced a strategic partnership with Five9 (Nasdaq: FIVN), a leading ... one of Avaya’s largest Platinum Business Partners, is a leading provider of ...
(Date:5/24/2016)... ... May 24, 2016 , ... How to Write Error Free Procedures, **Presented by ... , Human error is known to be the major cause of quality and production ... totally eliminated, many human performance problems can be prevented. , How to Write Error ...
(Date:5/24/2016)... Grand Bahama (PRWEB) , ... May 24, 2016 , ... ... pace. Such breakthroughs in adult stem cell therapy technology, protocols and patient results as ... this emerging field to become a more accessible standard of care for patients worldwide. ...
(Date:5/24/2016)... ... May 24, 2016 , ... Physical therapy ... focuses on repairing the musculoskeletal and neuromuscular systems of the human body without ... NYDNRehab began providing treatments for physical therapy in New York, including dynamic ...
(Date:5/24/2016)... , ... May 24, 2016 , ... A newly released ... heavily on their access to trusted resources, both in face-to-face interactions and online. In ... of Color,” researchers concluded that the creative use of mobile digital devices can be ...
Breaking Medicine News(10 mins):
(Date:5/23/2016)... New York , May 23, 2016 ... market report titled, " Exocrine Pancreatic Insufficiency Market - ... 2013 - 2023 ." According to the report, the ... a CAGR of 8.3% from 2015 to 2023 to ... insufficiency (EPI) is a condition characterized by the deficiency ...
(Date:5/23/2016)... 23, 2016 Clarifying Vision - ... Monitoring, and Vision Care What can be ... going to grow at the fastest rates? This ... assessing data, trends, opportunities and prospects. ... Discover the most lucrative areas in the industry and ...
(Date:5/23/2016)... Non-invasive diagnostic test realizes the ... ,Technology to be presented at Yissum’s booth, at IATI-BIOMED ... Company of the Hebrew University of Jerusalem announced ... Aurum Ventures MKI, the technology investment arm of Morris ... approach for early detection of multiple diseases by analyzing ...
Breaking Medicine Technology: