Navigation Links
Searching for shut eye: Penn study identifies possible sleep gene
Date:7/29/2008

PHILADELPHIA While scientists and physicians know what happens if you don't get six to eight hours of shut-eye a night, investigators have long been puzzled about what controls the actual need for sleep. Researchers at the University of Pennsylvania School of Medicine might have an answer, at least in fruit flies. In a recent study of fruit flies, they identified a gene that controls sleep.

"We spend -- or should spend -- a third of our lives sleeping," says Amita Sehgal, PhD, Professor of Neuroscience and an Investigator with the Howard Hughes Medical Institute (HHMI). "The idea that so much time is spent in sleep is intriguing. Also, sleep deprivation has serious health consequences and impairs cognitive function."

This study was published in the latest Science.

Fruit flies typically sleep 12 hours a day. Sehgal and her team studied 3,500 fruit flies and found mutants that survived on little to no sleep one to two hours a day or none at all. The sleepless flies had a mutation of a gene that Sehgal and her team have named Sleepless. They believe the Sleepless gene encodes a protein that affects whether potassium ion channels in the brain stay open or closed. When the channels are open, the brain is connected and working the fly is awake. When closed, the channel shuts down and the fly sleeps. The insomniac fruit flies had less of the Sleepless-produced protein.

The lack of sleep didn't come without consequences. The Sleepless fruit flies lived about half as long as fruit flies that did not carry the mutation. They also experience impaired coordination and restlessness in their few hours of sleep.

Sleep is regulated by two processes: circadian and homeostatic. Circadian regulation affects the timing of sleep, and the homeostatic mechanism affects the need for sleep. The Sleepless gene affects the homeostatic mechanism.

Sleep isn't just for humans it's been observed in everything from flies to
'/>"/>

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Regence Enables Members to Share Feedback With Each Other When Researching Health Care Provider Options
2. Charlie Rose Science Series to Focus on the Challenge of Researching and Implementing Effective Treatments for Diseases of the Developing World
3. Bariatric patients have 65% lower chance of complications at top hospitals: HealthGrades study
4. New study finds healthy children of Alzheimer patients show early brain changes
5. New study finds smoking predicts increased stroke risk for your spouse
6. Study provides clues to preventing and treating cancer spread
7. New AHRQ Study Finds Surgical Errors Cost Nearly $1.5 Billion Annually
8. Erectile dysfunction drugs allowed more chemotherapy to reach brain tumors in laboratory study
9. Study Disproves Belief That Hepatitis C Blunts HIV Drugs
10. Study shows emergency physicians have good first instincts in diagnosing heart attacks
11. Study suggests human visual system could make powerful computer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/13/2014)... Albany, New York (PRWEB) July 13, 2014 ... Share, Growth, Trends and Forecast 2013 - 2019 , ... the patients suffering from myopia or cataracts. The lenses ... crystalline. After the cataract surgery intraocular lens replaces the ... (PIOL) switches with original crystalline lens to deliver the ...
(Date:7/13/2014)... inexpensive, portable, microchip-based test for diagnosing type-1 diabetes ... better understand the disease, according to the device,s ... , Described in a paper to be published ... the test employs nanotechnology to detect type-1 diabetes ... the two main forms of diabetes mellitus, which ...
(Date:7/13/2014)... Recently, MillionaireCasket.com, a well-known casket manufacturer from China, ... Additionally, the company’s chief executive officer has announced a new ... are offered at discounted prices, from 15 to 26 percent ... are in huge demand in the current market. We are ... have a lot of high quality products for sale. Many ...
(Date:7/13/2014)... 13, 2014 The North American water storage ... 2013 to $5,450 million by 2018, at a CAGR of ... is expanding at a rapid pace in North America. The ... laws on water & wastewater storage and collection, and the ... market is expanding at a healthy rate in Canada, and ...
(Date:7/13/2014)... July 13, 2014 The report ... Molybdenum, Iron), Form (Chelated & Non Chelated), Application ... - Global Trends and Forecast to 2018” defines ... an analysis and forecasting of the global value ... the driving and restraining factors for the global ...
Breaking Medicine News(10 mins):Health News:Intraocular Lens (IOL) Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 2Health News:Intraocular Lens (IOL) Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 3Health News:Intraocular Lens (IOL) Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 4Health News:Stanford researchers invent nanotech microchip to diagnose type-1 diabetes 2Health News:Stanford researchers invent nanotech microchip to diagnose type-1 diabetes 3Health News:Stanford researchers invent nanotech microchip to diagnose type-1 diabetes 4Health News:Cheap Oak Caskets Recently Unveiled By China Casket Manufacturer MillionaireCasket.com 2Health News:North American Water Storage Systems Market is Expected to Reach $5,450 million by 2018 - New Report by MicroMarket Monitor 2Health News:North American Water Storage Systems Market is Expected to Reach $5,450 million by 2018 - New Report by MicroMarket Monitor 3Health News:Micronutrient Market Worth $6,474.6 Million by 2018 - A Report by MarketsandMarkets 2Health News:Micronutrient Market Worth $6,474.6 Million by 2018 - A Report by MarketsandMarkets 3Health News:Micronutrient Market Worth $6,474.6 Million by 2018 - A Report by MarketsandMarkets 4
... social growth might also see growing waistlines among their ... University and the University of Colorado. The ... improve conditions such as malnutrition and infectious disease, it ... "It,s a troubling finding," said Rice sociology ...
... from the NCAA will kick off a groundbreaking, long-term ... led by University of Michigan researchers and their colleagues ... to begin to fund a longitudinal study by the ... that includes three founding members from the University of ...
... Storrs HealthDay Reporter , TUESDAY, March 13 (HealthDay ... do with factors like race, age and where they live, ... to a new study. Researchers analyzed food questionnaires from ... and older in the continental United States, with a focus ...
... March 11 (HealthDay News) -- High school and college students around ... or sick on vacation can ruin the fun. The American ... take to prevent injuries and stay safe while traveling with their ... a person should go to the nearest ER so we can ...
... Madonna Behen HealthDay Reporter , THURSDAY, March 8 ... can take years off your life, but a new Israeli ... mid-80s, carrying some extra pounds might actually help you live ... that while obesity did increase the risk of dying for ...
... March 8, 2012 Research published today in the ... Ludwig Institute for Cancer Research (LICR) and Memorial Sloan-Kettering Cancer ... (ipilimumab), fostered a strong immune response and a favorable clinical ... of skin cancer. The size of both the tumor ...
Cached Medicine News:Health News:Economic and social growth of developing nations may increase obesity 2Health News:Groundbreaking, long-term study of head injuries among athletes kicks off with NCAA grant 2Health News:Groundbreaking, long-term study of head injuries among athletes kicks off with NCAA grant 3Health News:Race, Location Big Factors in American Diets 2Health News:Race, Location Big Factors in American Diets 3Health News:Spring Break Safety Tips to Keep Vacation Fun 2Health News:Could Fat Be Your Friend Over Age 85? 2Health News:Could Fat Be Your Friend Over Age 85? 3Health News:NEJM study shows combination treatments benefit melanoma patient 2
(Date:7/10/2014)... , July 10, 2014 Yesterday, ... Research,s (Moberg) medical device manufacturing facility. Rep. Kennedy ... advanced neurological monitors facilitate cutting-edge research in neurological ... Kennedy and mental health advocate, Garen Staglin ... dedicated to fostering fundamental changes that will radically ...
(Date:7/10/2014)... 2014   Ventana Medical Systems, Inc.  (Ventana), a ... entered into an agreement with Merck KGaA, Darmstadt, ... in the United States and ... KGaA,s biopharmaceutical division on the development and commercialization of ... Ventana,s proprietary diagnostic assays. In alignment with Merck KGaA,s ...
(Date:7/10/2014)... R.I. , July 10, 2014 CVS Caremark ... board of directors has approved a quarterly dividend of $0.275 ... dividend is payable on August 1, 2014, to holders of ... CVS Caremark is dedicated to helping people ... pharmacy company in the United States . ...
Breaking Medicine Technology:Representative Patrick Kennedy visits Moberg's medical device facility to discuss improvement in brain injury care 2Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 2Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 3
... Sept. 21 As consumer healthcare expenses rise, ... customer satisfaction has increased considerably from 2009, according ... National Pharmacy Study(SM) released today. ... http://www.newscom.com/cgi-bin/prnh/20050527/LAF028LOGO-a ) The study, now in ...
... 21 HealthWarehouse.com, Inc. (OTC Bulletin Board: ... Columbia Medical Associates, an outpatient clinic system offering medical ... partnership to offer patients a 30-day supply of more ... home delivery. Columbia Medical Associate,s "Columbia Care" ...
Cached Medicine Technology:J.D. Power and Associates Reports: As Consumers Shoulder More Healthcare Expenses, Cost Increasingly Drives Overall Customer Satisfaction With Pharmacies 2J.D. Power and Associates Reports: As Consumers Shoulder More Healthcare Expenses, Cost Increasingly Drives Overall Customer Satisfaction With Pharmacies 3J.D. Power and Associates Reports: As Consumers Shoulder More Healthcare Expenses, Cost Increasingly Drives Overall Customer Satisfaction With Pharmacies 4J.D. Power and Associates Reports: As Consumers Shoulder More Healthcare Expenses, Cost Increasingly Drives Overall Customer Satisfaction With Pharmacies 5HealthWarehouse.com Partners with Columbia Medical Associates to Bring Affordable Healthcare to Washington State 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: