Navigation Links
Scripps and Trius team up to develop new antibiotics with US Department of Defense grant
Date:9/20/2010

In an effort to tap into the vast potential of the oceans as a source for novel medical treatments, the Defense Threat Reduction Agency (DTRA), a part of the Department of Defense (DoD), has awarded San Diego-based Trius Therapeutics, Inc. a four-and-a-half year contract worth up to $29.5 million to collaborate with Scripps Institution of Oceanography at UC San Diego for the development of novel antibiotics directed against microorganisms that cause serious infections.

Trius will use its proprietary Focused Antisense Screening Technology (FAST) to identify the targets of antibacterial compounds from marine natural product libraries discovered by William Fenical, Distinguished Professor of Oceanography at Scripps Institution of Oceanography and Director of Scripps' Center for Marine Biotechnology and Biomedicine.

A pioneer in the field of marine biomedicine, Fenical has led efforts to explore the oceans in search of novel microbial sources that can lead to the development of new cures for a variety of diseases. Expeditions to Fiji, the Bahamas, and just off the Scripps Pier, to name a few destinations, have yielded promising drug compounds to treat cancer and other illnesses. The oceans, which remain largely unexplored, offer a broad diversity of environments that Fenical and his colleagues are examining for novel organisms and unique chemical structures.

Under the new DTRA award, Trius will apply its structure-based drug design capabilities to optimize antibacterial compounds for activity against biodefense pathogens such as Yersinia pestis, Francisella tularensis and Burkholderia pseudomallei. Trius believes that these compounds also will be active against drug-resistant pathogens involved in hospital-acquired infections.

"We are now facing an epidemic because drug resistance is growing at an alarming rate," said Fenical. "The oceans are a huge resource where biodiversity is greatest on our planet. The biomedical potent
'/>"/>

Contact: Mario Aguilera
scrippsnews@ucsd.edu
858-534-3624
University of California -- San Diego
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Scripps Health Begins Pioneering Study of Human Tumor Sequencing in Cancer Patients
2. Top Scientists Explore the Origin of Life in Annual Lasker Lecture at Scripps Research Institute Florida Campus
3. Scripps Blood & Marrow Transplant Program Celebrates 30th Anniversary of Providing Life-Saving Care
4. Scripps Memorial Hospital La Jolla First in San Diego to Achieve Magnet Nursing Re-designation
5. Scripps Announces Plans for Region's First Proton Therapy Center; $185 Million Facility to Offer Advanced Care to Cancer Patients
6. Scripps Research scientists share $2 million in Florida state research grants
7. Scripps Center for Executive Health Now Offers Genetic Testing
8. Scripps Research scientists uncover previously unknown natural mechanism that controls cocaine use
9. NIH awards Scripps Florida scientists $2.3 Million to develop drug addiction treatments
10. Scripps Research scientists solve long-standing mystery of protein quality control mechanism
11. Cochlear Appoints Switched on Media to Develop its SEO Across the Asia Pacific Region
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scripps and Trius team up to develop new antibiotics with US Department of Defense grant
(Date:1/22/2015)... Gabe’s Chemo Duck Program is pleased to announce the ... created for kids with cancer. The Chemo Duck App, available on ... with enjoyable games to help children of all ages living with ... to keep kids entertained, educated and at ease while waiting for ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 The Incredible Bulk ... Ben Pakulski to increase lean muscle by up to 30lbs ... caught the attention of HealthyandFitZone.com’s Stan Stevenson, prompting an investigative ... it is a step-by-step, scientific diet formula that allows the ...
(Date:1/22/2015)... AngelWeddingDress, the premier women’s dress supplier, has recently released ... website of AngelWeddingDress.com to find more details. , ... for a bridal party. AngelWeddingDress offers a variety of ... maternity wedding dresses are specially designed for 2015. , ...
(Date:1/22/2015)... January 22, 2015 A new white ... experience and person-centeredness in the long-term care environment as ... across the continuum. The paper, “The Power of Person-Centeredness ... perspectives and practices of the patient, resident and family ...
(Date:1/22/2015)... 22, 2015 For over 20 years, Dr. David ... and Vista area has treated just about every type of ... circumstances. And for those same twenty-plus years, the team at ... those injuries with the best possible doctor. With the ...
Breaking Medicine News(10 mins):Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2
... CAMBRIDGE, Mass., Oct 2 Biopure Corporation,(Nasdaq: BPUR ... became,effective at 12:01 a.m. October 2, 2007, with post-split ... today. The outstanding,warrants, including those trading on the OTCBB ... reduced and the exercise prices,increased by the 1-for-5 ratio. ...
... Positioned as Growth Platform, NEW YORK, and ... New-York-based private investment firm, announced today that,it has ... national,marketer of personal protective equipment, safety equipment, first ... America Corporation.,The transaction has a value of approximately ...
... Efforts for Pulmonary Study, SOLANA BEACH, ... LLC, a firm specializing in patient recruitment ... team of Regional Recruitment,Specialists(TM) in support of ... Obstructive Pulmonary Disease (COPD) for a recently ...
... YORK, Oct. 2, 2007 - When it comes to preventing ... Perhaps most surprising, women are more afraid of getting ... times more deaths per year. , These are among the ... of Texas M. D. Anderson Cancer Center and Prevention of ...
... Corey Goodman Steps Down; John Walker, Board Chair, Named Executive ... ... 1 Renovis,Inc. (Nasdaq: RNVS ), a biopharmaceutical company focused on ... of,neurological and inflammatory diseases, today announced that Corey Goodman,Ph.D., will step down ...
... cough ... suppressant, CHESTER, ... today announced that the Food and Drug,Administration (FDA) approved its supplemental ... Friday,Sept. 28, 2007. The Company will immediately commence distribution of grape,Delsym ...
Cached Medicine News:Health News:Biopure Announces Reverse Stock Split 2Health News:Biopure Announces Reverse Stock Split 3Health News:Caxton-Iseman Capital Acquires Conney Safety Products, LLC 2Health News:RESolutions Rapid Enrollment Solutions, LLC Mobilizes Team of Regional Recruitment Specialists(TM) 2Health News:M. D. Anderson-Prevention poll finds women can do more to prevent cancer...but aren't 2Health News:M. D. Anderson-Prevention poll finds women can do more to prevent cancer...but aren't 3Health News:Renovis Announces Management Changes 2Health News:Renovis Announces Management Changes 3Health News:Renovis Announces Management Changes 4Health News:Renovis Announces Management Changes 5
(Date:1/23/2015)...  iMD Companies, Inc. (ICBU) has repositioned itself as a holding ... a foothold in the hydroponic, hemp and medical marijuana sectors. ... in the sector, and recently partnering with the Chippewa Tribe ... medical marijuana, iMD is committing to bring its vision to ...
(Date:1/23/2015)... CAPE TOWN, South Africa , Jan. 23, 2015 ... and distributor of personal protective equipment for all forms ... include the flagship Leatt-Brace® neck brace, announced today that ... minicross racing federation, now requires all riders to wear ...
(Date:1/23/2015)... 23, 2015 Gem Pharmaceuticals announced today that the ... into the Company,s Phase 2 clinical trial.  This open-label ... lead compound, GPX-150 (an investigational medication), in approximately 30 ... Logo - http://photos.prnewswire.com/prnh/20150123/170966LOGO ...
Breaking Medicine Technology:iMD Companies Poised to Make Impact in Multi-Billion Dollar Medical Marijuana Sector With Recent Investments and Strategic Partnerships 2Leatt Announces Neck Braces Now Required For Motocross/Minicross Racing In Italy 2Leatt Announces Neck Braces Now Required For Motocross/Minicross Racing In Italy 3Gem Pharmaceuticals Announces Enrollment of Initial Patients in its Phase 2 Clinical Trial to Assess the Efficacy and Safety of GPX-150 in Sarcoma Patients 2
... children in the United States under the age of ... the disease goes beyond painful red, dry patches of ... altering—with nearly 50 percent of children reporting that they ... Laser ( www.XTRACLaser.com ) offers new hope for this ...
... Mass., June 8, 2011 Syndax Pharmaceuticals, a clinical-stage ... elected to the board of directors.  Ms. Morris most ... of the board of directors of Affymax, Inc., a ... in 2001 to develop a pipeline of synthetic peptide-based ...
Cached Medicine Technology:XTRAC Laser Provides New Hope for Children with Psoriasis 2XTRAC Laser Provides New Hope for Children with Psoriasis 3Syndax Pharmaceuticals Elects Arlene Morris to Board of Directors 2Syndax Pharmaceuticals Elects Arlene Morris to Board of Directors 3
... blood oximeters provide cardiologists with critical ... a patient's blood. The Oxicom series ... over a half-million saturation samples measured ... cost-effective oxygen saturation readings in less ...
We offer small and large pre-gelled Surface Electrodes suitable for EMG or EGG recordings....
We offer small and large pre-gelled Surface Electrodes suitable for EMG or EGG recordings....
We offer small and large pre-gelled Surface Electrodes suitable for EMG or EGG recordings....
Medicine Products: