Navigation Links
Scripps and Trius team up to develop new antibiotics with US Department of Defense grant
Date:9/20/2010

In an effort to tap into the vast potential of the oceans as a source for novel medical treatments, the Defense Threat Reduction Agency (DTRA), a part of the Department of Defense (DoD), has awarded San Diego-based Trius Therapeutics, Inc. a four-and-a-half year contract worth up to $29.5 million to collaborate with Scripps Institution of Oceanography at UC San Diego for the development of novel antibiotics directed against microorganisms that cause serious infections.

Trius will use its proprietary Focused Antisense Screening Technology (FAST) to identify the targets of antibacterial compounds from marine natural product libraries discovered by William Fenical, Distinguished Professor of Oceanography at Scripps Institution of Oceanography and Director of Scripps' Center for Marine Biotechnology and Biomedicine.

A pioneer in the field of marine biomedicine, Fenical has led efforts to explore the oceans in search of novel microbial sources that can lead to the development of new cures for a variety of diseases. Expeditions to Fiji, the Bahamas, and just off the Scripps Pier, to name a few destinations, have yielded promising drug compounds to treat cancer and other illnesses. The oceans, which remain largely unexplored, offer a broad diversity of environments that Fenical and his colleagues are examining for novel organisms and unique chemical structures.

Under the new DTRA award, Trius will apply its structure-based drug design capabilities to optimize antibacterial compounds for activity against biodefense pathogens such as Yersinia pestis, Francisella tularensis and Burkholderia pseudomallei. Trius believes that these compounds also will be active against drug-resistant pathogens involved in hospital-acquired infections.

"We are now facing an epidemic because drug resistance is growing at an alarming rate," said Fenical. "The oceans are a huge resource where biodiversity is greatest on our planet. The biomedical potent
'/>"/>

Contact: Mario Aguilera
scrippsnews@ucsd.edu
858-534-3624
University of California -- San Diego
Source:Eurekalert  

0

GOOD

Page: 1 2

Related medicine news :

1. Scripps Health Begins Pioneering Study of Human Tumor Sequencing in Cancer Patients
2. Top Scientists Explore the Origin of Life in Annual Lasker Lecture at Scripps Research Institute Florida Campus
3. Scripps Blood & Marrow Transplant Program Celebrates 30th Anniversary of Providing Life-Saving Care
4. Scripps Memorial Hospital La Jolla First in San Diego to Achieve Magnet Nursing Re-designation
5. Scripps Announces Plans for Region's First Proton Therapy Center; $185 Million Facility to Offer Advanced Care to Cancer Patients
6. Scripps Research scientists share $2 million in Florida state research grants
7. Scripps Center for Executive Health Now Offers Genetic Testing
8. Scripps Research scientists uncover previously unknown natural mechanism that controls cocaine use
9. NIH awards Scripps Florida scientists $2.3 Million to develop drug addiction treatments
10. Scripps Research scientists solve long-standing mystery of protein quality control mechanism
11. Cochlear Appoints Switched on Media to Develop its SEO Across the Asia Pacific Region
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scripps and Trius team up to develop new antibiotics with US Department of Defense grant
(Date:5/18/2013)... 18, 2013 http://www.resource4thepeople.com/defectivemedicaldevices/transvaginal-mesh-lawsuit.html ... consumers about transvaginal mesh failure lawsuits that ... reports that plaintiffs have won significant rulings ... , The rulings came in orders handed ... the Southern District of West Virginia, where ...
(Date:5/18/2013)... 2013 Three new locations will be ... wellness centers and one therapeutic dispensary. Patient Appreciation Fair ... weekend of May 25th – May 27th, particularly honoring ... All events will take place from 11:00 ... Elements Therapeutic Dispensary , 10580 S. State Route 69, ...
(Date:5/17/2013)... Allen J. Schultz, D.D.S., is making the ... available to residents of San Juan Capistrano. The ... rather than relying on a scalpel to cut the tissue ... works on tightly defined wavelengths to target the diseased tissue ... , Only about one in every hundred dental professionals is ...
(Date:5/17/2013)... Johnson & Johnson subsidiary DePuy Orthopaedics ... of metal-on-metal hip replacements. This comes after the company ... lawsuits and calls for increased regulation,** and after the ... Rottenstein Law Group LLP, a metal-on-metal hip implant law ... the market and notes that it maintains a comprehensive ...
(Date:5/17/2013)... OH (PRWEB) May 17, 2013 ... are an eye-catching, resilient, slip-resistant renovation tread ... Designed for new construction or staircase renovation projects, ... durability while providing a look to compliment building ... applications, but attractive enough for home stairs such ...
Breaking Medicine News(10 mins):Health News:2013 Alleged Transvaginal Mesh Complications Lawsuits Update: Resource4thePeople Reports Defendants Ordered to Provide Testimony, Documents 2Health News:2013 Alleged Transvaginal Mesh Complications Lawsuits Update: Resource4thePeople Reports Defendants Ordered to Provide Testimony, Documents 3Health News:2013 Alleged Transvaginal Mesh Complications Lawsuits Update: Resource4thePeople Reports Defendants Ordered to Provide Testimony, Documents 4Health News:Elements Honors Medical Marijuana Patients at Elements Health and Wellness Centers and Elements Therapeutic Dispensary 2Health News:Elements Honors Medical Marijuana Patients at Elements Health and Wellness Centers and Elements Therapeutic Dispensary 3Health News:Elements Honors Medical Marijuana Patients at Elements Health and Wellness Centers and Elements Therapeutic Dispensary 4Health News:San Clemente, CA Periodontist, Dr. Allen J. Schultz, Now Provides Laser Gum Disease Treatment to Southern Orange County Periodontal Disease Patients 2Health News:DePuy Announces It Will Stop Selling Metal-On-Metal Hip Implants, Notes Rottenstein Law Group LLP 2Health News:DePuy Announces It Will Stop Selling Metal-On-Metal Hip Implants, Notes Rottenstein Law Group LLP 3Health News:New Bold Step Renovation Stair Treads and Nosings from Martinson-Nicholls Add Slip Resistance to Stairs 2
... Quest Diagnostics,Incorporated (NYSE: DGX ), the world,s ... that its third-quarter,2008 results will be made public on ... will hold its quarterly conference call with investors,to discuss ... day., The public may access the conference call ...
... leapt to the forefront of American research universities for ... to a company that analyzes intellectual property. , The ... the prowess of their properties, raised Rice to No. ... public ranking of research universities. , "The results ...
... BALA CYNWYD, Pa., Oct. 8 Philadelphia Insurance,Companies (Nasdaq: ... Coaches" will tip,off for the American Cancer Society at ... PM., Sean Sweeney, PHLY,s Executive Vice President & ... back through fitness. More than,ten thousand Americans are struck ...
... Inc. (NYSE: WTW ) today announced the ... President, North America, effective November,3, 2008. McCormick, a ... management experience, will oversee the Company,s,North American meetings ... businesses and will be reporting to David P.,Kirchhoff, ...
... HMO, Inc. announced,today that it has teamed up with ... awareness in New York City of,stroke, the number three ... Health will provide support for the associations, campaigns,against cardiovascular ... Street Run & Heart Walk and the Power to ...
... a,non-partisan, non-profit organization offering free mental health services,to ... collaboration with,HelpPRO(R) -- a leading online therapist finder ... needed mental health professionals in,their community., Through ... Give,an Hour network offering their time and professional ...
Cached Medicine News:Health News:Quest Diagnostics to Release Third Quarter 2008 Financial Results 2Health News:Rice research gets high marks 2Health News:Philadelphia Insurance Companies Slam Dunk for Cancer 2Health News:Weight Watchers Names Steven C. McCormick as President, North America 2Health News:Weight Watchers Names Steven C. McCormick as President, North America 3Health News:Touchstone Health Partners with the American Heart Association and American Stroke Association to Fight Cardiovascular Disease Among Seniors 2Health News:HelpPRO and Give an Hour Join to Help Military Families Get Free Therapy Services 2
(Date:5/17/2013)... N.C. , May 17, 2013  Technology ... organizations communicate internally. Faced with a constantly evolving ... strategies and tactics for communicating with internal executives. ... of all the strategies, tactics and tools that ... In a new study, Best Practices, LLC ...
(Date:5/17/2013)... 2013  Sony Biotechnology Inc. ("Sony") today announced the launch ... 130um sorting chip.  Sony will also be exhibiting its newly ... Cell Sorter, the EC800 flow cytometer, and new SP6800 Spectral ... which will be held at the San Diego ... , from May 20 - 22.  ...
(Date:5/17/2013)... 17, 2013 /PRNewswire-iReach/ -- United Medical Education, a company ... (ACLS), Pediatric Advanced Life Support (PALS) and Basic Life ... ACLS online course manuals. In order to ... to build an account with the company. By offering ... United Medical Education is setting a precedent among similar ...
Breaking Medicine Technology:Internal Communication Strategies and Tactics that Resonate with Key Stakeholders and Drive Organizational Effectiveness 2Sony Delivers New Technology for Science to CYTO 2013 2ACLS Online Course Manuals are Now Available at No Cost through United Medical Education 2
... MYL ) today announced that its Mylan Institutional ... mL, 1000 mg/100 mL and 1500 mg/100 mL, for intravenous ... approved by the U.S. Food and Drug Administration (FDA), marks ... and 1500 mg) of premixed Levetiracetam will be supplied in ...
... Catalina Council of the Boy Scouts of America announced ... the Chemistry Merit Badge requirements through an event hosted ... Valley, Arizona. Boy Scout participants will have the chance ... under whose guidance they can participate in activities geared ...
Cached Medicine Technology:Mylan Launches Innovative Version of Antiepileptic Drug Levetiracetam 2Mylan Launches Innovative Version of Antiepileptic Drug Levetiracetam 3Catalina Council Boy Scouts Partner With Sanofi US Tucson Research Center to Host First-Ever Chemistry Merit Badge Program 2Catalina Council Boy Scouts Partner With Sanofi US Tucson Research Center to Host First-Ever Chemistry Merit Badge Program 3
... Sirolimus-eluting Coronary Stent consists of ... "sirolimus", a controlled-release polymer, and ... Upon placement, sirolimus elutes into ... the process of neointimal hyperplasia, ...
PT wires combine the enhanced durability of a linear elastic nitinol distal core and a highly resilient polymer tip. This provides excellent access in difficult cases involving severe tortuosity, tig...
Forte Guide Wire w/Markers: Front line use, 1:1 torque, excellent steering and tracking, sharp vessel images, floppy and moderate support....
Forte Guide Wire w/Markers: Front line use, 1:1 torque, excellent steering and tracking, sharp vessel images, floppy and moderate support....
Medicine Products: