Navigation Links
Scripps Research Institute scientists show protein linked to hunger also implicated in alcoholism
Date:9/14/2012

LA JOLLA, CA Researchers at The Scripps Research Institute have found new links between a protein that controls our urge to eat and brain cells involved in the development of alcoholism. The discovery points to new possibilities for designing drugs to treat alcoholism and other addictions.

The new study, published online ahead of print by the journal Neuropsychopharmacology, focuses on the peptide ghrelin, which is known to stimulate eating.

"This is the first study to characterize the effects of ghrelin on neurons in a brain region called the central nucleus of the amygdala," said team leader Scripps Research Institute Associate Professor Marisa Roberto, who was knighted last year by the Italian Republic for her work in the alcoholism field. "There is increasing evidence that the peptide systems regulating food consumption are also critical players in excessive alcohol consumption. These peptide systems have the potential to serve as targets for new therapies aimed at treating alcoholism."

Excessive alcohol use and alcoholism cause approximately 4 percent of deaths globally each year. In the United States, that translates to 79,000 deaths annually and $224 billion in healthcare and other economic costs, according to a 2011 report by the Centers for Disease Control and Prevention.

Key Brain Region

The brain region known as the central nucleus of the amygdala is thought to be a key region in the transition to alcohol dependence, that is, a biological change from experiencing a pleasant sensation upon the consumption of alcohol to the need to consume alcohol to relieve unpleasant, negative feelings due to the lack of its consumption. In animals addicted to alcohol, the central nucleus of the amygdala controls increased consumption.

"Given the importance of the central nucleus of the amygdala in alcohol dependence, we wanted to test ghrelin's effects in this region," said Maureen Cruz, the f
'/>"/>

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Scripps Research scientists show how memory B cells stay in class to fight different infections
2. Scripps Florida scientists awarded nearly $1.5 million to develop new approaches to treat cancer
3. Clinical trials start for stroke drug developed by Scripps Research, USC, and ZZ Biotech
4. Scripps Research scientists devise powerful new method for finding therapeutic antibodies
5. UCLA Brain Injury Research Center gets NCAA funding for research on sports concussions
6. NIH awards $20 million over 5 years to train next generation of global health researchers
7. Researchers develop a new cell and animal model of inflammatory breast cancer
8. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
9. Sexually abused boys at risk for more unsafe sex: UBC research
10. Researchers Find Gene Mutations That May Be a Key to Autism
11. LSUHSC research finds HPV-related head & neck cancers rising, highest in middle-aged white men
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scripps Research Institute scientists show protein linked to hunger also implicated in alcoholism
(Date:7/28/2015)... ... , ... Santa Rosa’s The Press Democrat announced its annual report of the very best facilities ... Heather Furnas took the top spot as the Best Cosmetic Surgeons in Sonoma County ... to be bestowed such a prestigious title. , The Press Democrat was Santa ...
(Date:7/28/2015)... ... 2015 , ... World Patent Marketing, a vertically integrated manufacturer ... makes shelling eggs an exact science. , “The global kitchen appliances market is ... Director of World Patent Marketing. “With a growth rate of 6.4%, market expansion ...
(Date:7/28/2015)... ... ... The Denver Foundation and Blair-Caldwell African American Research Library ... and narrative exploration of African American giving, which runs August 1-31 at the ... one of only ten cities to host “The Soul of Philanthropy Reframed and ...
(Date:7/28/2015)... ... July 28, 2015 , ... Autism is ... 68 children currently affected with the disorder. For these families, identifying and paying ... recovery is extremely daunting. That’s where Talk About Curing Autism (TACA), a national ...
(Date:7/28/2015)... ... 16, 2015 (PRWEB) July 28, 2015 , ... Nations Insurance ... insurance quotes to its clients, recently announced the launch of Commercial, Auto and ... their specific needs. , Liability automobile insurance policies are one popular type ...
Breaking Medicine News(10 mins):Health News:Dr. Canales and Dr. Furnas Honored as Sonoma County’s Best Cosmetic Surgeons 2Health News:Essential Bang For Your Buck Kitchen Items Presented By World Patent Marketing 2Health News:Essential Bang For Your Buck Kitchen Items Presented By World Patent Marketing 3Health News:Essential Bang For Your Buck Kitchen Items Presented By World Patent Marketing 4Health News:Essential Bang For Your Buck Kitchen Items Presented By World Patent Marketing 5Health News:"The Soul of Philanthropy Reframed and Exhibited” Comes to Denver 2Health News:National TACA Autism Conference Offers Hope and Help to Families Affected by Autism 2Health News:Nations Insurance Solutions Announces Auto, Motorcycle, and Commercial Business Insurance Quotes. 2
... 27 454 Life Sciences, a Roche,company, today ... the company,s Genome Sequencer(TM) FLX system to sequence ... The study,entitled "Whole-Genome Shotgun Sequencing of Mitochondria from ... in the journal Science. The study describes ...
... is a moron in the morning and a genius in ... were discovered by a new study performed by Vanderbilt University ... the National Academy of Sciences., This is the first example ... its biological clock, says Terry L. Page, the professor of ...
... Conseco, Inc. (NYSE:,CNO) will host a question and ... p.m. Eastern Daylight Time today. During the company,s long ... a service,provider prevented callers from accessing the Q & ... To access the conference call, dial (888) 251-7470 ...
... Sept. 27 The Patient,Advocate Foundation (PAF) -- ... tens of thousands of patients every year who,are ... financial or insurance,denials --announced this month the addition ... policy leaders and medical professionals ---,Roy Ramthun; Pearl ...
... leading cause of parasitic infections in U.S. , THURSDAY, ... genome of the intestinal parasite Giardia lamblia , ... in the United States. , That makes giardia the ... in the country, experts note. , People contract Giardia ...
... home team from the bleachers this fall, high school gridiron ... see anything out of the ordinary down on the field. ... the maroon helmets worn by the Unity High School Rockets, ... varsity team members are sporting helmets outfitted with the same ...
Cached Medicine News:Health News:454 Sequencing(TM): Science Paper Describes a Novel, Highly Efficient Method of Sequencing Ancient DNA; Sequences the Mitochondria of 10 Individual Mammoths to Prove It 2Health News:454 Sequencing(TM): Science Paper Describes a Novel, Highly Efficient Method of Sequencing Ancient DNA; Sequences the Mitochondria of 10 Individual Mammoths to Prove It 3Health News:Cockroaches are morons in the morning, geniuses in the evening 2Health News:Patient Advocate Foundation Welcomes Leading Health Care Experts to Executive Board of Directors 2Health News:Patient Advocate Foundation Welcomes Leading Health Care Experts to Executive Board of Directors 3Health News:Scientists Map Intestinal Bug's Genome 2Health News:High school footballers wearing special helmets to monitor brain injuries 2Health News:High school footballers wearing special helmets to monitor brain injuries 3
(Date:7/28/2015)... Research and Markets ( http://www.researchandmarkets.com/research/cng4gn/refurbished ) has ... Market - Global Forecasts to 2019" report to ... market is estimated to grow expected to reach $9.37 ... 2014 to 2019. Factors such ... financial constraints, increasing privatization in the healthcare sector, and ...
(Date:7/28/2015)...  PD-Rx Pharmaceuticals, Inc., a publicly held corporation, ... with Dobson Technologies, a fully-integrated outsourced IT provider, ... PD-Rx is an Application Service Provider ... Using Dobson Technologies, IaaS solution will allow PD-Rx ... regulatory compliance, and reduce operating expenses.  "The most ...
(Date:7/28/2015)... TAMPA, Fla. , July 28, 2015  For ... by their researchers, physicians and other inventors can be ... to market is difficult, and successes are rare. ... wants to change that. Medical Device ... technology licensed from universities, hospitals and physicians. MDI develops, ...
Breaking Medicine Technology:Refurbished Medical Equipment Market 2015 - Global Forecasts to 2019 2PD-Rx Partners With Dobson Technologies 2Medical Device Investments To Become Center Of Excellence For The Commercialization Of Innovative Medical Technologies 2
... ATLANTA, Dec. 13, 2011  GeoVax Labs, Inc. (OTCQB/OTCBB: GOVX), ... prevent and fight Human Immunodeficiency Virus (HIV) infections, announced ... Phase 1/2 clinical trial for the Company,s HIV/AIDS therapeutic ... vaccines for the treatment of persons who are HIV ...
... YORK, Dec. 13, 2011 Reportlinker.com announces ... available in its catalogue: ... Market Outlook to 2017 - Respiratory Devices, ... Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain ...
Cached Medicine Technology:GeoVax Labs' First Patient Inoculated in Phase 1/2 Clinical Trial for HIV/AIDS Therapeutic Vaccine 2GeoVax Labs' First Patient Inoculated in Phase 1/2 Clinical Trial for HIV/AIDS Therapeutic Vaccine 3United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 2United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 3United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 4United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 5United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 6United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 7United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 8United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 9United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 10United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 11United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 12United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 13United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 14United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 15United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 16United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 17United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 18United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 19United States Anesthesia and Respiratory Devices Market Outlook to 2017 - Respiratory Devices, Respiratory Measurement Devices, Airway and Anesthesia Devices, Anesthesia Machines, Sleep Apnea Diagnostic Systems, Pain Management Devices and Others 20
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: