Scripps Pioneers Individualized Medicine by Offering Genetic Testing to Stent...(er provider in California. Last year Sc...),Health

Date:10/7/2009

er provider in California. Last year, Scripps treated more than 45,000 cardiovascular patients. Scripps is currently designing the Scripps Cardiovascular Institute (SCI), which is planned to open in 2015.

"Knowing a patient's individualized risk has a tremendous impact on treatment decisions," said Dr. Paul Teirstein, head of interventional cardiology at Scripps Green Hospital and Scripps Clinic. "The point is to do everything we can to give patients the best possible outcomes. This kind of genomic screening gives us critical information we need to help patients."

Scripps patients carrying the gene risk variants will be considered for three treatment choices following their stent procedures, each on an individualized basis. Patients will either:

Be given a routine 75 milligram dose of Plavix with careful surveillance; Be given a 150 milligram dose of Plavix, which has recently been shown to be safe and effective in patients showing lack of response to Plavix; or Be given the newly approved medicine Effient (prasugrel), which is not affected by the gene variant Cytochrome (CYP) 2C19.

Scripps physicians will initially offer the genetic tests to elective stent patients before they undergo their procedures at Scripps Green Hospital. Eventually, Scripps may extend the offering to its other facilities across San Diego County.

Quest Diagnostics will perform the CYP2C19 testing for Scripps patients at its Quest Diagnostics Nichols Institute laboratory in San Juan Capistrano, Calif. The results will be transmitted to the treating physician and treatment choice will b
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