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Scripps Health Begins Pioneering Study of Human Tumor Sequencing in Cancer Patients
Date:2/17/2010

Research Aims to Develop Individualized Therapies for Cancer Treatment

SAN DIEGO (Vocus) February 17, 2010 -- Scripps Health, through the Scripps Translational Science Institute, is launching a first-of-its-kind clinical research trial for cancer patients that will analyze and compare the genomics of tumor tissue with the individual’s core (native, germ-line) DNA. The hope is the data will lead to individualized therapies for cancer patients.

“The science exists to allow us to sort out what are the new mutations that account for the development of the cancer, which will bring us closer to identifying the right course of treatment not only for each type of cancer, but for each individual patient,” said Dr. Eric Topol, chief academic officer of Scripps Health and principal investigator of the study.

Finding and targeting cancer mutations is a rapidly growing field and has already begun to transform the way cancer is treated. New technology has increased the understanding of genetic mutations that are associated with the development and progression of cancer. These new and highly advanced technologies are very expensive and labor-intensive.

Patients with a new diagnosis of cancer may elect to participate in this study. While participation in the study is not likely to provide direct benefit for participating patients, the data will be shared with each patient’s treating physician and the hope is that it will have a
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