Navigation Links
Screening mammograms catch second breast cancers early
Date:2/22/2011

More women are surviving longer after having early-stage breast cancer, but they are at risk of developing breast cancer again: a recurrence or a new cancer, in either breast. Annual screening (a.k.a. "surveillance") mammography has long been standard for these women, but only scant evidence on screening outcomes supported this practice. In the February 23, 2011 Journal of the American Medical Association, the most comprehensive relevant study to date shows yearly mammograms do detect second breast cancers early.

The Breast Cancer Surveillance Consortium (BCSC) study examined 12 years of information from 58,870 screening mammograms in 19,078 women who had had early-stage breast cancerand an equal number of screening mammograms in 55,315 women who had no such history and were matched for breast density, age, BCSC registry, and year of mammography.

With her BCSC colleagues, Nehmat Houssami, MBBS, PhD, an associate professor at the University of Sydney's School of Public Health and Sydney Medical School and a physician at the Royal Hospital for Women, in Australia, found that women with a personal history of breast cancer had double the cancer rates as those with no such history. Women who had had breast cancer had 655 second cancers within a year of screening mammography, and those with no prior breast cancer had 342 cancers, with cancer rates of 10.5 vs. 5.8 per 1,000 screens, respectively.

"The comprehensive data from the BCSC made it possible for us to carefully examine the outcomes of screening for both the previously affected (conserved) breast, as well as the opposite breast, at a population level," Dr Houssami said. "This is the first study in the world, to our knowledge, to provide a complete picture of the expected outcomes of mammography screening for women with a personal history of breast cancer."

"Mammography was effective at finding cancers early in women who had had cancer, but not quite as effective as in those who had not," Dr. Houssami said, "We found that both false positives and 'interval cancers' were higher, and mammography was not as sensitive at detecting invasive breast cancer, in women with a personal history of breast cancer." False positives mean that a mammogram suggests a breast cancer may be present, but after further testing it turns out not to be. Interval cancers are breast cancers that were not detected on screening mammography and are found between mammography screens, prompted by either breast symptoms or additional testing.

"Because of the risk of interval cancers, it's important that women seek medical care for any breast changes or concerns between mammograms," said Dr. Houssami's collaborator Diana Miglioretti, PhD, a senior investigator at Group Health Research Institute. "The good news is that most of the breast cancers detected in breast cancer survivors between mammography screens were early stage."

Interval-cancer rates were particularly high in women who were younger than 50, had extremely dense breasts, or received breast-conserving treatment (lumpectomy) without radiotherapy for their first cancer. "Our results suggest that we should consider more tailored screening strategies in these women, such as additional or alternate screening modalities in some groupsbut this needs further research," Dr. Miglioretti said.


'/>"/>

Contact: Rebecca Hughes
hughes.r@ghc.org
206-287-2055
Group Health Research Institute
Source:Eurekalert  

Related medicine news :

1. Higher volume reduces false positives in screening mammography
2. Worlds largest lung cancer screening conference to address benefits of CT scans
3. Breast cancer screening with MRI benefits women with radiation therapy history
4. Screening for cervical cancer low for immigrant women
5. Repeat MRI screening for breast cancer results in fewer false positives
6. Study finds MRSA screening saves hospitals money
7. More Screenings May Explain Higher Chlamydia Rates Among Minorities
8. Biodesign hosts international consortium on screening for lung cancer
9. Predeployment Mental Health Screening May Help Troops
10. New Osteoporosis Screening Recommendations Issued
11. Geography May Influence Colon Cancer Screening Rates
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Screening mammograms catch second breast cancers early
(Date:2/14/2016)... ... February 14, 2016 , ... Many eating ... professionals near their residence. The nature of the illnesses requires ongoing supervision, therapy ... time allotted at work to make traditional appointments. These people struggle to maintain ...
(Date:2/13/2016)... ... February 13, 2016 , ... Good news for retinal patients ... area to offer AngioPlex™ Optical Coherence Tomography (OCT) Angiography, imaging technology used to ... diabetic retinopathy, and other vascular conditions. , In just a few seconds, OCT ...
(Date:2/13/2016)... Angeles, California (PRWEB) , ... February 13, 2016 , ... ... help landing a date for the big day. A great outfit, flawless hair, and ... ashtray, they might as well resign themselves to a night at home with Rover. ...
(Date:2/13/2016)... ... ... individuals looking to lead a healthy lifestyle have decreased carbohydrate consumption and increased their ... delved into this niche allowing those giving up their beloved pasta a chance to ... of protein and only 7 grams of carbohydrates per 50 gram serving--a ratio that ...
(Date:2/13/2016)... FL (PRWEB) , ... February 13, 2016 , ... The ... environmental impact of American businesses. , The increasingly modern world of instantaneous consumption ... often on non-renewable energy sources such as oil and coal, which pollutes our air, ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... 2016  Aralez Pharmaceuticals Inc. (Nasdaq: ARLZ ) ... will ring the Nasdaq Closing Bell at the Nasdaq ... at 4:00 p.m. ET on Tuesday, February 16, ... Adrian Adams , will perform the honorary bell ... p.m. ET.  A live webcast will be available at: ...
(Date:2/12/2016)... , Maharashtra, February 12, 2016 ... research report titled Chronic Inflammation Global Clinical Trials ... snapshot of the global clinical trials landscape along ... trials by Region, Country (G7 & E7), Trial ... status and reviews top companies involved and enlists ...
(Date:2/11/2016)... Laboratory glassware and plasticware include ... may range from microscope slides to large storage boxes ... borosilicate glass because of its low weight and resistance ... started gaining popularity over the past decade when it ... with plastic in several applications due to its resistance ...
Breaking Medicine Technology: