Navigation Links
Scott & White Healthcare pathologist is co-investigator on breast cancer study
Date:2/23/2010

In a laboratory study published in the journal Cancer Research, Scott & White Healthcare anatomic pathologist Arundhati Rao, M.D. is a co-investigator looking at the ways in which estrogen can interfere with how chemotherapy does its job in destroying breast cancer cells. The most common type of breast cancer is "estrogen-receptor positive" breast cancer.

Velusamy Rangasamy and Ajay Rana, Ph.D., are also the lead authors on the study and are based at Loyola University Medical Center in Chicago where Dr. Rana is a professor of pharmacology.

"What we know is that not all breast tumors are the same and if a tumor is estrogen-receptor positive, it's possible that chemotherapy isn't going to be as effective as it could be," said Dr. Rao. "This is why we see some breast cancer patients on chemo that isn't working like it should. With this additional information regarding estrogen, it could help us create more targeted therapies in the future."

"These findings are important because efficiently killing estrogen receptor positive (ER+) breast cancer cells with currently available chemotherapy is a challenging task and many times these ER+ breast tumors don't respond to classical chemotherapy," said Dr. Rana. "Our research identified an alternative cellular protein which can serve as a viable target for ER+ breast cancer treatment."

Dr. Rao went on to say that "with this research we found that in order to make cancer drugs work better, we may need to give patients a different drug and this could possibly shorten the duration of their chemotherapy course if we knew more."

"Our work suggests that any drugs/agents that will activate this protein will sensitize the ER+ breast cancer cells toward commonly used chemotherapies. We have been working to find the drugs/agents that can activate this protein and kill the ER+ cancer cells," said Dr. Rana.

Dr. Rana explained that "these findings are encouraging but further research is needed to find how this cellular pathway could be utilized to target estrogen positive breast cancer cells."


'/>"/>

Contact: Katherine Voss
kvoss@swmail.sw.org
254-724-4097
Scott & White Healthcare
Source:Eurekalert

Related medicine news :

1. Scott & White Memorial Hospital uses device to revolutionize treatment of traumatic aortic injury
2. Trustmark and HealthFitness Announce Early Termination of Hart-Scott-Rodino Waiting Period
3. Scott Roeder Trial: Randall Terry, Operation Rescue Founder and Insurrecta Nex Members to Attend Trial in Wichita
4. New study shows TGen spin-off boosts Scottsdale economy
5. Let Us Mute Our Praise for Scott Brown - a "Moderate" Child-Killer - and Seek to Replace Him With a True Pro-Lifer in Two Years, Says Randall Terry
6. Scott & White Healthcare researching treatments for rare cancers
7. Julian Lennon and James Scott Cook Release New Charity Single LUCY to Raise Awareness and Funds for Lupus Research
8. Dr. Daniel Von Hoff named honoree of Scottsdale Healthcare Foundation Honor Ball
9. Valley Health Invention Making National Splash Showcased at Scottsdale Civic Center Gallery
10. Affordable Acupuncture Greeted with Open Arms by Scottsdale and Phoenix Communities
11. Dip into a Healthy Holiday with the Taste of Texas Oncology's Holly Jolly Biscotti
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a leading Health and ... Applying the Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing CBD ... that can be easily incorporated into liquid products, while reducing costs to end users. ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes , ... mock evacuation of the facility as part of a disaster drill on October 3rd. ... EMS and Shelton City Emergency Manager, as well as the Connecticut Long Term ...
(Date:10/13/2017)... ... ... Ellevate Network, the leading network for professional women, brought together some of ... their inaugural Summit in New York City in June. The event was livestreamed with ... 3 million. To watch the Mobilize Women video, click here . , ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... will be giving viewers the lowdown on sciatica in a new episode of ... that focuses on current events and innovation and investigates each subject in-depth with ...
(Date:10/13/2017)... ... ... “America On The Brink”: the Christian history of the United States and ... of published author, William Nowers. Captain Nowers and his wife, Millie, have six ... years in the Navy. Following his career as a naval aviator and carrier ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... AMSTERDAM , Sept. 25, 2017   ... Trial Master File solutions, today—from the IQPC Trial ... Amsterdam , NL)—announced that EastHORN Clinical Services ... its clinical programs and TMF management. EastHORN, a ... Montrium,s eTMF platform to increase transparency to enable ...
(Date:9/22/2017)... DIEGO , Sept. 22, 2017 AVACEN ... medical device is now successfully helping those with the ... Fibromyalgia diagnosed Amanda in Essex, ... dressed and washing my hair, experiencing no sleep at ... in painful spasm… I cannot recommend [the AVACEN 100] ...
(Date:9/18/2017)... 18, 2017 EpiVax, Inc. ("EpiVax") ... and immune engineering, today announced a new ... (H7N9) vaccine. ... influenza and presents a challenge for traditional ... to be effective. Using state-of-the-art bioinformatics and molecular ...
Breaking Medicine Technology: