Navigation Links
Scientists win funding to study new treatment for severe chronic pain

Scientists at the University of Liverpool are leading a 1.5 million project to study `immunoglobulin', a type of drug which has been shown to ease complex regional pain syndrome (CRPS).

The team, from the University of Liverpool and the Walton Centre, who have already conducted previous work with this drug type, will now trial `immunoglobulin' in a larger group of patients who have suffered from CRPS for between one and five years. The Medical Research Council (MRC)-funded study will start to recruit patients in March 2013 and results are expected to be published in 2016/17.

Dr Andres Goebel, from the Institute of Translational Medicine who is leading the study, said: "The immunoglobulin technology is an entirely new way of treating severe chronic pain. It may help people with CRPS whose pain was previously virtually untreatable.

"This is also a sign of recognition, by one of the most prestigious research funding bodies in the UK, of the value of developing novel ways of treating patients with chronic pain, which causes such a burden in the general population.

"Using immunoglobulin treatment at a low dose (0.5g/kg) has very few side effects. We hope that we will eventually be able to demonstrate that this treatment is good value for money, and that it can be introduced into NHS practice, although additional studies will be required to achieve that goal."

CRPS is an unexplained condition that usually develops after an injury or trauma to a limb, and continues after the injury has healed. CPRS I, formerly called Reflex Sympathetic Dystrophy, can arise after any type of injury. CRPS II, previously called causalgia (a term coined in the American Civil War when it was first diagnosed), follows partial damage to a nerve.

In some cases the pain can be so severe that patients request amputation, only to find that the pain returns in the stump. CRPS pain can improve within one year after the injury, but if it is still unchanged after 12 months (longstanding CRPS), then it will often not improve at all. Longstanding CRPS affects about 1 in 2,000 people in the UK. More follows

Contact: Sarah Stamper
University of Liverpool

Related medicine news :

1. A*STAR scientists identify potential drug target for inflammatory diseases including cancers
2. Scientists at Mainz University identify inhibitor of myelin formation in the central nervous system
3. Scientists Track Activity in Rappers Brains
4. Scientists ID Gene Mutation That May Triple Alzheimers Risk
5. Kessler Foundation scientists report negative impact of long-term caregiving on cognition
6. John Templeton Foundation grant supports Princeton neuroscientists to study cognitive control
7. Scientists discover how stomach cancer spreads
8. How do cells tell time? Scientists develop single-cell imaging to watch the cell clock
9. Scientists Find Gene Differences in Nonsmokers With Lung Cancer
10. Scientists at IRB BARCELONA discover a key process that allows colon cancer to metastasize
11. Scientists uncover a new pathway that regulates information processing in the brain
Post Your Comments:
(Date:11/30/2015)... ... November 30, 2015 , ... During the ... for caregivers and held two webinars on topics of ‘Medical and Palliative Care ... charge at . , With a loved one's diagnosis of mesothelioma, ...
(Date:11/30/2015)... , ... November 30, 2015 , ... ... and dermatology, is proud to announce that its ThermiRFR temperature controlled radiofrequency platform ... is an innovative multi-application radiofrequency platform which uses temperature as a clinical endpoint. ...
(Date:11/30/2015)... Fla. (PRWEB) , ... November 30, 2015 , ... ... opened the driverless vehicle experience this summer, ushering in a new era of ... percent driverless and electric shuttle, will continue to offer guests an up-close look ...
(Date:11/30/2015)... ... 2015 , ... On Saturday, October 24th, 2015, at the Mill Race Park ... a 5K walk known as “Making Strides Against Breast Cancer”. Patients and staff members ... located in Battle Creek, joined in for this campaign that sought to raise donations ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... annual fundraising campaign to raise funds for its research, education, support, and advocacy ... the organization’s annual funding. , The Mesothelioma Applied Research Foundation, which also goes ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... BANNOCKBURN, Ill. , Nov. 30, 2015 ... ), a global biopharmaceutical leader dedicated to ... diseases and underserved medical conditions, today announced ... [Antihemophilic Factor (Recombinant), PEGylated], an extended circulating ... hemophilia A based on full-length ADVATE [Antihemophilic ...
(Date:11/30/2015)... HONG KONG, Nov. 30, 2015 (HK$,000)For the Six Months Ended 30 September ... Service Income , 421,979 , 384,242 ... , 34,719 , (18.3) Medical ... , 16.1 Medical Devices and Accessories Sales , ... Chinese Herbal Medicines Sales , 2,822 , ...
(Date:11/30/2015)... November 30, 2015 --> ... "Dental Lasers Market by Product (Soft Tissue, All Tissue, Dental ... (Hospitals, Clinics), and Geography - Global Forecast to 2020", published ... 2020, at a CAGR of 5.2% during the forecast period ... data Tables and 62 Figures spread through 167 P ...
Breaking Medicine Technology: